SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IDI'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2G70_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1n7j	PHENYLETHANOLAMINE N-METHYLTRANSFERASE (Homo sapiens)	12 / 12	TYR A 27 GLN A 86 PHE A 102 LEU A 103 ASP A 158 VAL A 159 HIS A 160 ALA A 181 PHE A 182 CYH A 183 VAL A 187 TYR A 222	SAH A2002 (-3.6A) SAH A2002 ( 4.2A) SAH A2002 (-4.4A) SAH A2002 (-3.9A) SAH A2002 (-3.6A) SAH A2002 (-3.5A) SAH A2002 (-4.1A) SAH A2002 (-3.3A) IDI A3003 ( 3.4A) SAH A2002 (-3.4A) SAH A2002 (-4.3A) IDI A3003 (-3.8A)	0.48A	2g70A-1n7jA: 47.1	2g70A-1n7jA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2G70_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1n7j	PHENYLETHANOLAMINE N-METHYLTRANSFERASE (Homo sapiens)	12 / 12	TYR A 27 GLN A 86 PHE A 102 LEU A 103 ASP A 158 VAL A 159 HIS A 160 ALA A 181 PHE A 182 CYH A 183 VAL A 187 TYR A 222	SAH A2002 (-3.6A) SAH A2002 ( 4.2A) SAH A2002 (-4.4A) SAH A2002 (-3.9A) SAH A2002 (-3.6A) SAH A2002 (-3.5A) SAH A2002 (-4.1A) SAH A2002 (-3.3A) IDI A3003 ( 3.4A) SAH A2002 (-3.4A) SAH A2002 (-4.3A) IDI A3003 (-3.8A)	0.50A	2g70B-1n7jA: 46.5	2g70B-1n7jA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2G72_A_SAMA2001_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1n7j	PHENYLETHANOLAMINE N-METHYLTRANSFERASE (Homo sapiens)	12 / 12	TYR A 27 THR A 83 PHE A 102 LEU A 103 ASP A 158 VAL A 159 HIS A 160 ALA A 181 PHE A 182 CYH A 183 VAL A 187 TYR A 222	SAH A2002 (-3.6A) SAH A2002 (-2.9A) SAH A2002 (-4.4A) SAH A2002 (-3.9A) SAH A2002 (-3.6A) SAH A2002 (-3.5A) SAH A2002 (-4.1A) SAH A2002 (-3.3A) IDI A3003 ( 3.4A) SAH A2002 (-3.4A) SAH A2002 (-4.3A) IDI A3003 (-3.8A)	0.23A	2g72A-1n7jA: 47.0	2g72A-1n7jA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	2G72_B_SAMB2002_0 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1n7j	PHENYLETHANOLAMINE N-METHYLTRANSFERASE (Homo sapiens)	12 / 12	TYR A 27 THR A 83 GLN A 86 PHE A 102 LEU A 103 ILE A 157 VAL A 159 HIS A 160 ALA A 181 CYH A 183 VAL A 187 TYR A 222	SAH A2002 (-3.6A) SAH A2002 (-2.9A) SAH A2002 ( 4.2A) SAH A2002 (-4.4A) SAH A2002 (-3.9A) SAH A2002 (-4.7A) SAH A2002 (-3.5A) SAH A2002 (-4.1A) SAH A2002 (-3.3A) SAH A2002 (-3.4A) SAH A2002 (-4.3A) IDI A3003 (-3.8A)	0.41A	2g72B-1n7jA: 46.0	2g72B-1n7jA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HCD_A_LNRA2001_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1n7j	PHENYLETHANOLAMINE N-METHYLTRANSFERASE (Homo sapiens)	9 / 9	ASN A 39 TYR A 40 ARG A 44 VAL A 53 LYS A 57 PHE A 182 GLU A 219 TYR A 222 ASP A 267	IDI A3003 ( 3.9A) SAH A2002 (-4.6A) IDI A3003 (-4.1A) IDI A3003 ( 4.6A) IDI A3003 ( 4.1A) IDI A3003 ( 3.4A) IDI A3003 (-3.1A) IDI A3003 (-3.8A) IDI A3003 (-3.8A)	0.33A	3hcdA-1n7jA: 47.6	3hcdA-1n7jA: 100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3HCD_B_LNRB2002_1 (PHENYLETHANOLAMINE N-METHYLTRANSFERASE)	1n7j	PHENYLETHANOLAMINE N-METHYLTRANSFERASE (Homo sapiens)	12 / 12	TYR A 35 ASN A 39 TYR A 40 ARG A 44 VAL A 53 LYS A 57 PHE A 182 GLU A 219 TYR A 222 MET A 258 ASP A 267 VAL A 269	SAH A2002 ( 4.4A) IDI A3003 ( 3.9A) SAH A2002 (-4.6A) IDI A3003 (-4.1A) IDI A3003 ( 4.6A) IDI A3003 ( 4.1A) IDI A3003 ( 3.4A) IDI A3003 (-3.1A) IDI A3003 (-3.8A) IDI A3003 (-4.2A) IDI A3003 (-3.8A) None	0.37A	3hcdB-1n7jA: 46.9	3hcdB-1n7jA: 100.00

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2G70_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1n7j","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","Homo sapiens",12,"TYR A  27;GLN A  86;PHE A 102;LEU A 103;ASP A 158;VAL A 159;HIS A 160;ALA A 181;PHE A 182;CYH A 183;VAL A 187;TYR A 222","SAH A2002 (-3.6A);SAH A2002 ( 4.2A);SAH A2002 (-4.4A);SAH A2002 (-3.9A);SAH A2002 (-3.6A);SAH A2002 (-3.5A);SAH A2002 (-4.1A);SAH A2002 (-3.3A);IDI A3003 ( 3.4A);SAH A2002 (-3.4A);SAH A2002 (-4.3A);IDI A3003 (-3.8A)","0.48A","2g70A-1n7jA:47.1",null],["2G70_B_SAMB2002_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1n7j","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","Homo sapiens",12,"TYR A  27;GLN A  86;PHE A 102;LEU A 103;ASP A 158;VAL A 159;HIS A 160;ALA A 181;PHE A 182;CYH A 183;VAL A 187;TYR A 222","SAH A2002 (-3.6A);SAH A2002 ( 4.2A);SAH A2002 (-4.4A);SAH A2002 (-3.9A);SAH A2002 (-3.6A);SAH A2002 (-3.5A);SAH A2002 (-4.1A);SAH A2002 (-3.3A);IDI A3003 ( 3.4A);SAH A2002 (-3.4A);SAH A2002 (-4.3A);IDI A3003 (-3.8A)","0.50A","2g70B-1n7jA:46.5","2g70A-1n7jA:100.00"],["2G72_A_SAMA2001_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1n7j","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","Homo sapiens",12,"TYR A  27;THR A  83;PHE A 102;LEU A 103;ASP A 158;VAL A 159;HIS A 160;ALA A 181;PHE A 182;CYH A 183;VAL A 187;TYR A 222","SAH A2002 (-3.6A);SAH A2002 (-2.9A);SAH A2002 (-4.4A);SAH A2002 (-3.9A);SAH A2002 (-3.6A);SAH A2002 (-3.5A);SAH A2002 (-4.1A);SAH A2002 (-3.3A);IDI A3003 ( 3.4A);SAH A2002 (-3.4A);SAH A2002 (-4.3A);IDI A3003 (-3.8A)","0.23A","2g72A-1n7jA:47.0","2g70B-1n7jA:100.00"],["2G72_B_SAMB2002_0","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1n7j","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","Homo sapiens",12,"TYR A  27;THR A  83;GLN A  86;PHE A 102;LEU A 103;ILE A 157;VAL A 159;HIS A 160;ALA A 181;CYH A 183;VAL A 187;TYR A 222","SAH A2002 (-3.6A);SAH A2002 (-2.9A);SAH A2002 ( 4.2A);SAH A2002 (-4.4A);SAH A2002 (-3.9A);SAH A2002 (-4.7A);SAH A2002 (-3.5A);SAH A2002 (-4.1A);SAH A2002 (-3.3A);SAH A2002 (-3.4A);SAH A2002 (-4.3A);IDI A3003 (-3.8A)","0.41A","2g72B-1n7jA:46.0","2g72A-1n7jA:100.00"],["3HCD_A_LNRA2001_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1n7j","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","Homo sapiens",9,"ASN A  39;TYR A  40;ARG A  44;VAL A  53;LYS A  57;PHE A 182;GLU A 219;TYR A 222;ASP A 267","IDI A3003 ( 3.9A);SAH A2002 (-4.6A);IDI A3003 (-4.1A);IDI A3003 ( 4.6A);IDI A3003 ( 4.1A);IDI A3003 ( 3.4A);IDI A3003 (-3.1A);IDI A3003 (-3.8A);IDI A3003 (-3.8A)","0.33A","3hcdA-1n7jA:47.6","2g72B-1n7jA:100.00"],["3HCD_B_LNRB2002_1","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","1n7j","PHENYLETHANOLAMINE N-METHYLTRANSFERASE","Homo sapiens",12,"TYR A  35;ASN A  39;TYR A  40;ARG A  44;VAL A  53;LYS A  57;PHE A 182;GLU A 219;TYR A 222;MET A 258;ASP A 267;VAL A 269","SAH A2002 ( 4.4A);IDI A3003 ( 3.9A);SAH A2002 (-4.6A);IDI A3003 (-4.1A);IDI A3003 ( 4.6A);IDI A3003 ( 4.1A);IDI A3003 ( 3.4A);IDI A3003 (-3.1A);IDI A3003 (-3.8A);IDI A3003 (-4.2A);IDI A3003 (-3.8A);None","0.37A","3hcdB-1n7jA:46.9","3hcdA-1n7jA:100.00"]]