SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'IAC'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1AQB_A_RTLA185_0 (RETINOL-BINDINGPROTEIN) |
5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) | 5 / 10 | LEU A 25ALA A 339VAL A 140MET A 366LEU A 349 | NoneIAC A 702 (-4.5A)NoneNoneNone | 1.41A | 1aqbA-5kodA:undetectable | 1aqbA-5kodA:15.78 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1VPO_H_TESH1010_1 (ANTI-TESTOSTERONE(HEAVY CHAIN)ANTI-TESTOSTERONE(LIGHT CHAIN)) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 12 | SER A 272ALA A 450GLY A 451LEU A 429PHE A 467 | NoneNoneNoneNAD A 700 (-4.5A)IAC A 701 (-4.5A) | 1.28A | 1vpoH-5iuwA:undetectable1vpoL-5iuwA:undetectable | 1vpoH-5iuwA:17.351vpoL-5iuwA:19.96 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WG7_B_CHDB303_0 (CYTOCHROME C OXIDASESUBUNIT 1CYTOCHROME C OXIDASESUBUNIT 2CYTOCHROME C OXIDASESUBUNIT 6A2,MITOCHONDRIAL) |
5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) | 5 / 11 | GLY A 495GLN A 319THR A 323PHE A 232GLY A 235 | NoneNoneNoneIAC A 702 (-4.6A)None | 1.27A | 3wg7A-5kodA:2.33wg7B-5kodA:undetectable3wg7T-5kodA:undetectable | 3wg7A-5kodA:20.723wg7B-5kodA:17.513wg7T-5kodA:9.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4A84_A_DXCA1161_0 (MAJOR POLLENALLERGEN BET V 1-A) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 12 | PRO A 166TYR A 487VAL A 161ALA A 174MET A 172 | NAD A 700 (-4.2A)NoneNoneNoneIAC A 701 ( 3.8A) | 1.48A | 4a84A-5iuwA:undetectable | 4a84A-5iuwA:15.34 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 4FR8_A_TNGA601_1 (ALDEHYDEDEHYDROGENASE,MITOCHONDRIAL) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 6 / 11 | ASN A 168PHE A 169MET A 173TRP A 176CYH A 302ASP A 459 | NAD A 700 ( 3.0A)IAC A 701 (-3.7A)NAD A 700 (-3.9A)NoneIAC A 701 ( 2.8A)IAC A 701 (-3.0A) | 1.10A | 4fr8A-5iuwA:57.8 | 4fr8A-5iuwA:43.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OT2_A_NPSA601_1 (SERUM ALBUMIN) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 12 | PHE A 467TYR A 458GLY A 468SER A 473SER A 306 | IAC A 701 (-4.5A)NoneNoneNoneNone | 1.44A | 4ot2A-5iuwA:undetectable | 4ot2A-5iuwA:21.86 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ZBR_A_NPSA602_1 (SERUM ALBUMIN) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 12 | PHE A 467TYR A 458GLY A 468SER A 473SER A 306 | IAC A 701 (-4.5A)NoneNoneNoneNone | 1.45A | 4zbrA-5iuwA:undetectable | 4zbrA-5iuwA:22.11 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5FHZ_A_REAA602_1 (ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 7 / 12 | GLY A 123ASN A 168PHE A 169MET A 173TRP A 176CYH A 302THR A 303 | NoneNAD A 700 ( 3.0A)IAC A 701 (-3.7A)NAD A 700 (-3.9A)NoneIAC A 701 ( 2.8A)IAC A 701 ( 4.2A) | 0.61A | 5fhzA-5iuwA:56.4 | 5fhzA-5iuwA:42.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5FHZ_A_REAA602_1 (ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 12 | GLY A 124ASN A 168PHE A 169TRP A 176CYH A 302 | NoneNAD A 700 ( 3.0A)IAC A 701 (-3.7A)NoneIAC A 701 ( 2.8A) | 1.11A | 5fhzA-5iuwA:56.4 | 5fhzA-5iuwA:42.14 | ||
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target. | 5FHZ_D_READ602_1 (ALDEHYDEDEHYDROGENASE FAMILY1 MEMBER A3) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 6 / 12 | GLY A 123ASN A 168MET A 173TRP A 176CYH A 302THR A 303 | NoneNAD A 700 ( 3.0A)NAD A 700 (-3.9A)NoneIAC A 701 ( 2.8A)IAC A 701 ( 4.2A) | 0.63A | 5fhzD-5iuwA:56.7 | 5fhzD-5iuwA:42.14 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5X19_B_CHDB302_0 (CYTOCHROME C OXIDASESUBUNIT 1CYTOCHROME C OXIDASESUBUNIT 2CYTOCHROME C OXIDASESUBUNIT 6A2,MITOCHONDRIAL) |
5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) | 5 / 11 | GLY A 495GLN A 319THR A 323PHE A 232GLY A 235 | NoneNoneNoneIAC A 702 (-4.6A)None | 1.33A | 5x19A-5kodA:0.15x19B-5kodA:undetectable5x19T-5kodA:undetectable | 5x19A-5kodA:20.725x19B-5kodA:17.515x19T-5kodA:9.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XDQ_B_CHDB304_0 (CYTOCHROME C OXIDASESUBUNIT 1CYTOCHROME C OXIDASESUBUNIT 2CYTOCHROME C OXIDASESUBUNIT 6A2,MITOCHONDRIAL) |
5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) | 5 / 11 | GLY A 495GLN A 319THR A 323PHE A 232GLY A 235 | NoneNoneNoneIAC A 702 (-4.6A)None | 1.27A | 5xdqA-5kodA:0.55xdqB-5kodA:undetectable5xdqT-5kodA:undetectable | 5xdqA-5kodA:20.725xdqB-5kodA:17.515xdqT-5kodA:9.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZCO_B_CHDB302_0 (CYTOCHROME C OXIDASESUBUNIT 1CYTOCHROME C OXIDASESUBUNIT 2CYTOCHROME C OXIDASESUBUNIT 6A2,MITOCHONDRIAL) |
5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) | 5 / 11 | GLY A 495GLN A 319THR A 323PHE A 232GLY A 235 | NoneNoneNoneIAC A 702 (-4.6A)None | 1.29A | 5zcoA-5kodA:1.35zcoB-5kodA:undetectable5zcoT-5kodA:undetectable | 5zcoA-5kodA:20.725zcoB-5kodA:17.515zcoT-5kodA:9.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5ZCP_B_CHDB301_0 (CYTOCHROME C OXIDASESUBUNIT 1CYTOCHROME C OXIDASESUBUNIT 2CYTOCHROME C OXIDASESUBUNIT 6A2,MITOCHONDRIAL) |
5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) | 5 / 11 | GLY A 495GLN A 319THR A 323PHE A 232GLY A 235 | NoneNoneNoneIAC A 702 (-4.6A)None | 1.32A | 5zcpA-5kodA:2.25zcpB-5kodA:undetectable5zcpT-5kodA:undetectable | 5zcpA-5kodA:20.725zcpB-5kodA:17.515zcpT-5kodA:9.60 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6CI6_A_NBOA606_1 (SERUM ALBUMIN) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 12 | PHE A 467TYR A 458GLY A 468SER A 473SER A 306 | IAC A 701 (-4.5A)NoneNoneNoneNone | 1.40A | 6ci6A-5iuwA:undetectable | 6ci6A-5iuwA:9.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GIQ_T_PCFT101_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 1,MITOCHONDRIALCYTOCHROME B-C1COMPLEX SUBUNIT 9CYTOCHROME B-C1COMPLEX SUBUNITRIESKE,MITOCHONDRIAL) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 4 / 8 | GLY A 270SER A 272ASN A 168VAL A 301 | NoneNoneNAD A 700 ( 3.0A)IAC A 701 ( 4.1A) | 0.94A | 6giqL-5iuwA:undetectable6giqP-5iuwA:undetectable6giqT-5iuwA:undetectable | 6giqL-5iuwA:23.676giqP-5iuwA:17.696giqT-5iuwA:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6GIQ_T_PCFT101_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 1,MITOCHONDRIALCYTOCHROME B-C1COMPLEX SUBUNIT 9CYTOCHROME B-C1COMPLEX SUBUNITRIESKE,MITOCHONDRIAL) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 4 / 8 | MET A 173GLY A 270SER A 272VAL A 301 | NAD A 700 (-3.9A)NoneNoneIAC A 701 ( 4.1A) | 1.08A | 6giqL-5iuwA:undetectable6giqP-5iuwA:undetectable6giqT-5iuwA:undetectable | 6giqL-5iuwA:23.676giqP-5iuwA:17.696giqT-5iuwA:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_I_PCFI101_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 1,MITOCHONDRIALCYTOCHROME B-C1COMPLEX SUBUNIT 9CYTOCHROME B-C1COMPLEX SUBUNITRIESKE,MITOCHONDRIAL) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 11 | GLY A 270SER A 272ALA A 431ASN A 168VAL A 301 | NoneNoneNoneNAD A 700 ( 3.0A)IAC A 701 ( 4.1A) | 1.24A | 6hu9A-5iuwA:1.06hu9E-5iuwA:undetectable6hu9I-5iuwA:undetectable | 6hu9A-5iuwA:23.306hu9E-5iuwA:15.976hu9I-5iuwA:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_I_PCFI101_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 1,MITOCHONDRIALCYTOCHROME B-C1COMPLEX SUBUNIT 9CYTOCHROME B-C1COMPLEX SUBUNITRIESKE,MITOCHONDRIAL) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 11 | MET A 173GLY A 270SER A 272ALA A 431VAL A 301 | NAD A 700 (-3.9A)NoneNoneNoneIAC A 701 ( 4.1A) | 1.42A | 6hu9A-5iuwA:1.06hu9E-5iuwA:undetectable6hu9I-5iuwA:undetectable | 6hu9A-5iuwA:23.306hu9E-5iuwA:15.976hu9I-5iuwA:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_T_PCFT101_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 1,MITOCHONDRIALCYTOCHROME B-C1COMPLEX SUBUNIT 9CYTOCHROME B-C1COMPLEX SUBUNITRIESKE,MITOCHONDRIAL) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 10 | GLY A 270SER A 272ALA A 431ASN A 168VAL A 301 | NoneNoneNoneNAD A 700 ( 3.0A)IAC A 701 ( 4.1A) | 1.18A | 6hu9L-5iuwA:undetectable6hu9P-5iuwA:undetectable6hu9T-5iuwA:undetectable | 6hu9L-5iuwA:23.306hu9P-5iuwA:15.976hu9T-5iuwA:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6HU9_T_PCFT101_0 (CYTOCHROME B-C1COMPLEX SUBUNIT 1,MITOCHONDRIALCYTOCHROME B-C1COMPLEX SUBUNIT 9CYTOCHROME B-C1COMPLEX SUBUNITRIESKE,MITOCHONDRIAL) |
5iuw | ALDEHYDEDEHYDROGENASE FAMILYPROTEIN (Pseudomonassyringaegroupgenomosp.3) | 5 / 10 | MET A 173GLY A 270SER A 272ALA A 431VAL A 301 | NAD A 700 (-3.9A)NoneNoneNoneIAC A 701 ( 4.1A) | 1.41A | 6hu9L-5iuwA:undetectable6hu9P-5iuwA:undetectable6hu9T-5iuwA:undetectable | 6hu9L-5iuwA:23.306hu9P-5iuwA:15.976hu9T-5iuwA:8.79 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 6NKN_B_CHDB304_0 (CYTOCHROME C OXIDASESUBUNIT 1CYTOCHROME C OXIDASESUBUNIT 2CYTOCHROME C OXIDASESUBUNIT 6A2,MITOCHONDRIAL) |
5kod | INDOLE-3-ACETICACID-AMIDOSYNTHETASE GH3.5 (Arabidopsisthaliana) | 5 / 11 | GLY A 495GLN A 319THR A 323PHE A 232GLY A 235 | NoneNoneNoneIAC A 702 (-4.6A)None | 1.32A | 6nknA-5kodA:0.16nknB-5kodA:undetectable6nknT-5kodA:undetectable | 6nknA-5kodA:20.726nknB-5kodA:17.516nknT-5kodA:9.60 |