SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'I1N'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5DV4_A_NMYA601_1
(CCR4-NOT
TRANSCRIPTION
COMPLEX SUBUNIT
6-LIKE)		 2ibn INOSITOL OXYGENASE
(Homo
sapiens) 		5 / 12 LEU A 254
HIS A 194
PRO A 224
ASP A 195
LEU A 185
 None
FE  A 704 ( 3.5A)
None
I1N  A 710 ( 4.8A)
None
 1.40A 5dv4A-2ibnA:
undetectable		 5dv4A-2ibnA:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_A_SAMA301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2ibn INOSITOL OXYGENASE
(Homo
sapiens) 		3 / 3 THR A 143
SER A 221
ASP A  85
 None
I1N  A 710 (-2.3A)
I1N  A 710 (-3.1A)
 0.68A 5kvaA-2ibnA:
undetectable		 5kvaA-2ibnA:
19.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 2ibn INOSITOL OXYGENASE
(Homo
sapiens) 		3 / 3 THR A 143
SER A 221
ASP A  85
 None
I1N  A 710 (-2.3A)
I1N  A 710 (-3.1A)
 0.66A 5kvaB-2ibnA:
undetectable		 5kvaB-2ibnA:
19.10