SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'I1E'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAX_B_CSCB1384_1 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	3szb	ALDEHYDE DEHYDROGENASE (Homo sapiens)	5 / 12	LEU A 119 THR A 186 TYR A 412 LYS A 416 HIS A 413	I1E A1001 ( 4.8A) None None None None	1.39A	2vaxB-3szbA: 0.0	2vaxB-3szbA: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2VAX_I_CSCI1384_1 (ACETYL-COA--DEACETYL CEPHALOSPORIN C ACETYLTRANSFERASE)	3szb	ALDEHYDE DEHYDROGENASE (Homo sapiens)	5 / 12	LEU A 119 THR A 186 TYR A 412 LYS A 416 HIS A 413	I1E A1001 ( 4.8A) None None None None	1.41A	2vaxI-3szbA: 0.0	2vaxI-3szbA: 21.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YDO_A_ADNA400_1 (ADENOSINE RECEPTOR A2A)	3szb	ALDEHYDE DEHYDROGENASE (Homo sapiens)	5 / 12	LEU A 119 LEU A 51 ASN A 238 ILE A 285 SER A 142	I1E A1001 ( 4.8A) None None None None	1.29A	2ydoA-3szbA: undetectable	2ydoA-3szbA: 21.29