SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HSX'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A84_A_DXCA1160_0
(MAJOR POLLEN
ALLERGEN BET V 1-A)		 5vn4 ADENINE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE
(Trypanosoma
brucei) 		5 / 12 ASP A 146
VAL A 172
VAL A 131
ILE A 112
LEU A 169
 HSX  A 302 (-2.8A)
None
None
None
None
 1.27A 4a84A-5vn4A:
undetectable		 4a84A-5vn4A:
21.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X7P_B_ACRB1421_1
(GLYCOSIDE HYDROLASE
FAMILY 31
ALPHA-GLUCOSIDASE)		 5vn4 ADENINE
PHOSPHORIBOSYLTRANSF
ERASE, PUTATIVE
(Trypanosoma
brucei) 		4 / 6 GLU A 127
TYR A 117
GLY A 153
GLY A 152
 None
None
HSX  A 302 (-3.9A)
HSX  A 302 (-3.5A)
 0.94A 5x7pB-5vn4A:
undetectable		 5x7pB-5vn4A:
11.99