SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HSO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1K2S_A_H4BA1760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.29A 1k2sA-1h3jA:
0.0
1k2sB-1h3jA:
0.0		 1k2sA-1h3jA:
22.14
1k2sB-1h3jA:
22.14
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KAR_A_HSMA502_1
(HISTIDINOL
DEHYDROGENASE)		 1kae HISTIDINOL
DEHYDROGENASE
(Escherichia
coli) 		6 / 9 LEU A 138
SER A 140
HIS A 262
ASP A 360
TYR A 361
HIS A 367
 HSO  A1001 ( 4.1A)
HSO  A1001 (-3.5A)
ZN  A1101 ( 3.3A)
HSO  A1001 ( 2.7A)
HSO  A1001 (-4.4A)
HSO  A1001 (-3.5A)
 0.23A 1karA-1kaeA:
57.4
1karB-1kaeA:
56.1		 1karA-1kaeA:
100.00
1karB-1kaeA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1KAR_B_HSMB503_1
(HISTIDINOL
DEHYDROGENASE)		 1kae HISTIDINOL
DEHYDROGENASE
(Escherichia
coli) 		6 / 9 LEU A 138
SER A 140
HIS A 262
ASP A 360
TYR A 361
HIS A 367
 HSO  A1001 ( 4.1A)
HSO  A1001 (-3.5A)
ZN  A1101 ( 3.3A)
HSO  A1001 ( 2.7A)
HSO  A1001 (-4.4A)
HSO  A1001 (-3.5A)
 0.21A 1karA-1kaeA:
57.4
1karB-1kaeA:
56.1		 1karA-1kaeA:
100.00
1karB-1kaeA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LZX_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.32A 1lzxA-1h3jA:
0.0
1lzxB-1h3jA:
0.0		 1lzxA-1h3jA:
22.14
1lzxB-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 1m00A-1h3jA:
0.0
1m00B-1h3jA:
0.0		 1m00A-1h3jA:
22.14
1m00B-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1M00_B_H4BB1760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 1m00A-1h3jA:
0.0
1m00B-1h3jA:
0.0		 1m00A-1h3jA:
22.14
1m00B-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 1om4A-1h3jA:
0.0
1om4B-1h3jA:
0.0		 1om4A-1h3jA:
22.84
1om4B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1OM4_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.34A 1om4A-1h3jA:
0.0
1om4B-1h3jA:
0.0		 1om4A-1h3jA:
22.84
1om4B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6J_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.29A 1p6jA-1h3jA:
0.0
1p6jB-1h3jA:
0.0		 1p6jA-1h3jA:
22.84
1p6jB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.46A 1p6kA-1h3jA:
0.0
1p6kB-1h3jA:
0.0		 1p6kA-1h3jA:
23.20
1p6kB-1h3jA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1P6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.48A 1p6kA-1h3jA:
0.0
1p6kB-1h3jA:
0.0		 1p6kA-1h3jA:
23.20
1p6kB-1h3jA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1RS7_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 1rs7A-1h3jA:
0.0
1rs7B-1h3jA:
0.0		 1rs7A-1h3jA:
22.84
1rs7B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 1zzqA-1h3jA:
0.0
1zzqB-1h3jA:
0.0		 1zzqA-1h3jA:
22.51
1zzqB-1h3jA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZZQ_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 1zzqA-1h3jA:
0.0
1zzqB-1h3jA:
0.0		 1zzqA-1h3jA:
22.51
1zzqB-1h3jA:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6H_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 8 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 2g6hA-1h3jA:
0.0
2g6hB-1h3jA:
undetectable		 2g6hA-1h3jA:
22.14
2g6hB-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 2g6kA-1h3jA:
0.0
2g6kB-1h3jA:
0.0		 2g6kA-1h3jA:
22.14
2g6kB-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6K_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.28A 2g6kA-1h3jA:
0.0
2g6kB-1h3jA:
0.0		 2g6kA-1h3jA:
22.14
2g6kB-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 2g6mA-1h3jA:
undetectable
2g6mB-1h3jA:
0.0		 2g6mA-1h3jA:
22.14
2g6mB-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2G6M_B_H4BB761_1
(NITRIC-OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.28A 2g6mA-1h3jA:
0.0
2g6mB-1h3jA:
0.0		 2g6mA-1h3jA:
22.14
2g6mB-1h3jA:
22.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3N_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3b3nA-1h3jA:
0.0
3b3nB-1h3jA:
0.0		 3b3nA-1h3jA:
22.84
3b3nB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3O_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3b3oA-1h3jA:
0.0
3b3oB-1h3jA:
0.0		 3b3oA-1h3jA:
22.84
3b3oB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_A_H4BA760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3b3pA-1h3jA:
0.0
3b3pB-1h3jA:
1.2		 3b3pA-1h3jA:
22.84
3b3pB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B3P_B_H4BB760_1
(NITRIC-OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 8 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.30A 3b3pA-1h3jA:
1.3
3b3pB-1h3jA:
undetectable		 3b3pA-1h3jA:
22.84
3b3pB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3hsnA-1h3jA:
0.0
3hsnB-1h3jA:
0.0		 3hsnA-1h3jA:
22.84
3hsnB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSN_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.28A 3hsnA-1h3jA:
0.0
3hsnB-1h3jA:
0.0		 3hsnA-1h3jA:
22.84
3hsnB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 3hsoA-1h3jA:
0.0
3hsoB-1h3jA:
0.0		 3hsoA-1h3jA:
22.84
3hsoB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSO_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.30A 3hsoA-1h3jA:
0.0
3hsoB-1h3jA:
0.0		 3hsoA-1h3jA:
22.84
3hsoB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.28A 3hspA-1h3jA:
0.0
3hspB-1h3jA:
0.0		 3hspA-1h3jA:
22.84
3hspB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HSP_B_H4BB1760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.28A 3hspA-1h3jA:
0.0
3hspB-1h3jA:
0.0		 3hspA-1h3jA:
22.84
3hspB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3jt4A-1h3jA:
0.0
3jt4B-1h3jA:
0.0		 3jt4A-1h3jA:
22.84
3jt4B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT4_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.32A 3jt4A-1h3jA:
0.0
3jt4B-1h3jA:
0.0		 3jt4A-1h3jA:
22.84
3jt4B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 3jt5A-1h3jA:
0.0
3jt5B-1h3jA:
0.0		 3jt5A-1h3jA:
22.84
3jt5B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT6_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3jt6A-1h3jA:
0.0
3jt6B-1h3jA:
0.0		 3jt6A-1h3jA:
22.84
3jt6B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT7_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.28A 3jt7A-1h3jA:
0.0
3jt7B-1h3jA:
0.0		 3jt7A-1h3jA:
22.84
3jt7B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT8_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3jt8A-1h3jA:
0.0
3jt8B-1h3jA:
0.0		 3jt8A-1h3jA:
22.84
3jt8B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 3jt9A-1h3jA:
0.0
3jt9B-1h3jA:
0.0		 3jt9A-1h3jA:
22.84
3jt9B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JT9_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.31A 3jt9A-1h3jA:
undetectable
3jt9B-1h3jA:
0.0		 3jt9A-1h3jA:
22.84
3jt9B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JTA_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3jtaA-1h3jA:
0.0
3jtaB-1h3jA:
0.0		 3jtaA-1h3jA:
22.84
3jtaB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3jwtA-1h3jA:
0.0
3jwtB-1h3jA:
undetectable		 3jwtA-1h3jA:
22.61
3jwtB-1h3jA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JWT_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.24A 3jwtA-1h3jA:
0.0
3jwtB-1h3jA:
undetectable		 3jwtA-1h3jA:
22.61
3jwtB-1h3jA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.27A 3jx0A-1h3jA:
0.0
3jx0B-1h3jA:
0.0		 3jx0A-1h3jA:
23.20
3jx0B-1h3jA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3jx1A-1h3jA:
0.0
3jx1B-1h3jA:
0.0		 3jx1A-1h3jA:
23.20
3jx1B-1h3jA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3JX1_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 8 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 3jx1A-1h3jA:
0.0
3jx1B-1h3jA:
0.0		 3jx1A-1h3jA:
23.20
3jx1B-1h3jA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.30A 3n2rA-1h3jA:
0.0
3n2rB-1h3jA:
0.0		 3n2rA-1h3jA:
22.84
3n2rB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N2R_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.32A 3n2rA-1h3jA:
0.0
3n2rB-1h3jA:
0.0		 3n2rA-1h3jA:
22.84
3n2rB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5V_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3n5vA-1h3jA:
0.0
3n5vB-1h3jA:
0.0		 3n5vA-1h3jA:
22.84
3n5vB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N5Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3n5zA-1h3jA:
undetectable
3n5zB-1h3jA:
undetectable		 3n5zA-1h3jA:
22.84
3n5zB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 5 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.38A 3n62A-1h3jA:
1.4
3n62B-1h3jA:
0.0		 3n62A-1h3jA:
23.20
3n62B-1h3jA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N62_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 5 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.38A 3n62A-1h3jA:
1.4
3n62B-1h3jA:
0.0		 3n62A-1h3jA:
23.20
3n62B-1h3jA:
23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.29A 3n65A-1h3jA:
0.0
3n65B-1h3jA:
0.0		 3n65A-1h3jA:
22.84
3n65B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3N65_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 5 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.38A 3n65A-1h3jA:
0.0
3n65B-1h3jA:
0.0		 3n65A-1h3jA:
22.84
3n65B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLK_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3nlkA-1h3jA:
0.0
3nlkB-1h3jA:
0.0		 3nlkA-1h3jA:
22.61
3nlkB-1h3jA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3nlmA-1h3jA:
0.0
3nlmB-1h3jA:
0.0		 3nlmA-1h3jA:
22.84
3nlmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 3nlmA-1h3jA:
0.0
3nlmB-1h3jA:
0.0		 3nlmA-1h3jA:
22.84
3nlmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLO_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.24A 3nloA-1h3jA:
undetectable
3nloB-1h3jA:
0.0		 3nloA-1h3jA:
22.61
3nloB-1h3jA:
22.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 3nlvA-1h3jA:
1.3
3nlvB-1h3jA:
0.0		 3nlvA-1h3jA:
22.84
3nlvB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 3nlvA-1h3jA:
1.3
3nlvB-1h3jA:
0.0		 3nlvA-1h3jA:
22.84
3nlvB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3nlxA-1h3jA:
undetectable
3nlxB-1h3jA:
0.0		 3nlxA-1h3jA:
22.84
3nlxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 3nlxA-1h3jA:
0.0
3nlxB-1h3jA:
0.0		 3nlxA-1h3jA:
22.84
3nlxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 3nlzA-1h3jA:
0.0
3nlzB-1h3jA:
0.0		 3nlzA-1h3jA:
22.84
3nlzB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NLZ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.27A 3nlzA-1h3jA:
0.0
3nlzB-1h3jA:
0.0		 3nlzA-1h3jA:
22.84
3nlzB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3nm0A-1h3jA:
0.0
3nm0B-1h3jA:
0.0		 3nm0A-1h3jA:
22.84
3nm0B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NM0_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.32A 3nm0A-1h3jA:
0.0
3nm0B-1h3jA:
0.0		 3nm0A-1h3jA:
22.84
3nm0B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNY_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3nnyA-1h3jA:
0.0
3nnyB-1h3jA:
0.0		 3nnyA-1h3jA:
22.84
3nnyB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NNZ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 3nnzA-1h3jA:
0.0
3nnzB-1h3jA:
0.0		 3nnzA-1h3jA:
22.84
3nnzB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3pneA-1h3jA:
0.0
3pneB-1h3jA:
undetectable		 3pneA-1h3jA:
22.84
3pneB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNE_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.27A 3pneA-1h3jA:
0.0
3pneB-1h3jA:
0.0		 3pneA-1h3jA:
22.84
3pneB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3pnfA-1h3jA:
0.0
3pnfB-1h3jA:
0.0		 3pnfA-1h3jA:
22.84
3pnfB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNF_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 3pnfA-1h3jA:
0.0
3pnfB-1h3jA:
0.0		 3pnfA-1h3jA:
22.84
3pnfB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3pngA-1h3jA:
0.0
3pngB-1h3jA:
0.0		 3pngA-1h3jA:
22.84
3pngB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3PNG_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 3pngA-1h3jA:
0.0
3pngB-1h3jA:
0.0		 3pngA-1h3jA:
22.84
3pngB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3q99A-1h3jA:
0.0
3q99B-1h3jA:
0.0		 3q99A-1h3jA:
22.84
3q99B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q99_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.31A 3q99A-1h3jA:
0.0
3q99B-1h3jA:
0.0		 3q99A-1h3jA:
22.84
3q99B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3q9aA-1h3jA:
0.0
3q9aB-1h3jA:
0.0		 3q9aA-1h3jA:
22.84
3q9aB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3Q9A_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.34A 3q9aA-1h3jA:
0.0
3q9aB-1h3jA:
0.0		 3q9aA-1h3jA:
22.84
3q9aB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQJ_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 3rqjA-1h3jA:
0.0
3rqjB-1h3jA:
0.0		 3rqjA-1h3jA:
22.84
3rqjB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQK_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 3rqkA-1h3jA:
undetectable
3rqkB-1h3jA:
0.0		 3rqkA-1h3jA:
22.84
3rqkB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.22A 3rqlA-1h3jA:
0.0
3rqlB-1h3jA:
0.0		 3rqlA-1h3jA:
22.84
3rqlB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQL_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 8 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 3rqlA-1h3jA:
undetectable
3rqlB-1h3jA:
0.0		 3rqlA-1h3jA:
22.84
3rqlB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3rqmA-1h3jA:
0.0
3rqmB-1h3jA:
0.0		 3rqmA-1h3jA:
22.84
3rqmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQM_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 3rqmA-1h3jA:
0.0
3rqmB-1h3jA:
0.0		 3rqmA-1h3jA:
22.84
3rqmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3rqnA-1h3jA:
0.0
3rqnB-1h3jA:
0.0		 3rqnA-1h3jA:
22.84
3rqnB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RQN_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.24A 3rqnA-1h3jA:
0.0
3rqnB-1h3jA:
0.0		 3rqnA-1h3jA:
22.84
3rqnB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SVP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 3svpA-1h3jA:
0.0
3svpB-1h3jA:
0.0		 3svpA-1h3jA:
22.84
3svpB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.28A 3tylA-1h3jA:
0.0
3tylB-1h3jA:
0.0		 3tylA-1h3jA:
22.84
3tylB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 3tymA-1h3jA:
0.0
3tymB-1h3jA:
0.0		 3tymA-1h3jA:
22.84
3tymB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TYN_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3tynA-1h3jA:
0.0
3tynB-1h3jA:
0.0		 3tynA-1h3jA:
22.84
3tynB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.28A 3ufoA-1h3jA:
0.0
3ufoB-1h3jA:
0.0		 3ufoA-1h3jA:
22.84
3ufoB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 3ufpA-1h3jA:
undetectable
3ufpB-1h3jA:
0.0		 3ufpA-1h3jA:
22.84
3ufpB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.32A 3ufpA-1h3jA:
undetectable
3ufpB-1h3jA:
0.0		 3ufpA-1h3jA:
22.84
3ufpB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFR_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.34A 3ufrA-1h3jA:
undetectable
3ufrB-1h3jA:
undetectable		 3ufrA-1h3jA:
22.84
3ufrB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFS_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.30A 3ufsA-1h3jA:
0.0
3ufsB-1h3jA:
0.0		 3ufsA-1h3jA:
22.84
3ufsB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFT_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3uftA-1h3jA:
0.0
3uftB-1h3jA:
0.0		 3uftA-1h3jA:
22.84
3uftB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 3ufuA-1h3jA:
0.0
3ufuB-1h3jA:
0.0		 3ufuA-1h3jA:
22.84
3ufuB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 3ufuA-1h3jA:
0.0
3ufuB-1h3jA:
0.0		 3ufuA-1h3jA:
22.84
3ufuB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3UFV_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 3ufvA-1h3jA:
0.0
3ufvB-1h3jA:
0.0		 3ufvA-1h3jA:
22.84
3ufvB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C39_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.42A 4c39A-1h3jA:
0.0
4c39B-1h3jA:
0.0		 4c39A-1h3jA:
22.84
4c39B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.22A 4caoA-1h3jA:
undetectable
4caoB-1h3jA:
0.0		 4caoA-1h3jA:
22.84
4caoB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 4capA-1h3jA:
0.0
4capB-1h3jA:
0.0		 4capA-1h3jA:
22.84
4capB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CAQ_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4caqA-1h3jA:
0.0
4caqB-1h3jA:
1.0		 4caqA-1h3jA:
22.84
4caqB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4ctpA-1h3jA:
0.0
4ctpB-1h3jA:
0.0		 4ctpA-1h3jA:
22.84
4ctpB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTU_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 4ctuA-1h3jA:
0.0
4ctuB-1h3jA:
1.2		 4ctuA-1h3jA:
22.84
4ctuB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTW_A_H4BA1718_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 4ctwA-1h3jA:
0.0
4ctwB-1h3jA:
0.0		 4ctwA-1h3jA:
22.84
4ctwB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CTX_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4ctxA-1h3jA:
0.0
4ctxB-1h3jA:
0.0		 4ctxA-1h3jA:
22.84
4ctxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 4cx5A-1h3jA:
0.0
4cx5B-1h3jA:
0.0		 4cx5A-1h3jA:
22.84
4cx5B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX5_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.24A 4cx5A-1h3jA:
0.0
4cx5B-1h3jA:
0.0		 4cx5A-1h3jA:
22.84
4cx5B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4CX6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.38A 4cx6A-1h3jA:
0.0
4cx6B-1h3jA:
0.0		 4cx6A-1h3jA:
22.84
4cx6B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 4d1nA-1h3jA:
0.0
4d1nB-1h3jA:
0.0		 4d1nA-1h3jA:
22.59
4d1nB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.27A 4d1nA-1h3jA:
0.0
4d1nB-1h3jA:
0.0		 4d1nA-1h3jA:
22.59
4d1nB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D1N_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.35A 4d1nC-1h3jA:
0.0
4d1nD-1h3jA:
0.0		 4d1nC-1h3jA:
22.59
4d1nD-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Y_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4d2yA-1h3jA:
0.0
4d2yB-1h3jA:
0.0		 4d2yA-1h3jA:
22.84
4d2yB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4d2zA-1h3jA:
0.0
4d2zB-1h3jA:
0.0		 4d2zA-1h3jA:
22.84
4d2zB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D2Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 4d2zA-1h3jA:
0.0
4d2zB-1h3jA:
0.0		 4d2zA-1h3jA:
22.84
4d2zB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D30_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4d30A-1h3jA:
0.0
4d30B-1h3jA:
0.0		 4d30A-1h3jA:
22.84
4d30B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D3B_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4d3bA-1h3jA:
0.0
4d3bB-1h3jA:
0.0		 4d3bA-1h3jA:
22.84
4d3bB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4d7oA-1h3jA:
0.0
4d7oB-1h3jA:
0.0		 4d7oA-1h3jA:
22.84
4d7oB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4D7O_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.25A 4d7oA-1h3jA:
0.0
4d7oB-1h3jA:
0.0		 4d7oA-1h3jA:
22.84
4d7oB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4euxA-1h3jA:
0.0
4euxB-1h3jA:
0.0		 4euxA-1h3jA:
22.84
4euxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.33A 4euxA-1h3jA:
0.0
4euxB-1h3jA:
0.0		 4euxA-1h3jA:
22.84
4euxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4fvwA-1h3jA:
0.0
4fvwB-1h3jA:
0.0		 4fvwA-1h3jA:
22.84
4fvwB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.33A 4fvwA-1h3jA:
0.0
4fvwB-1h3jA:
0.0		 4fvwA-1h3jA:
22.84
4fvwB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4fvxA-1h3jA:
0.0
4fvxB-1h3jA:
1.0		 4fvxA-1h3jA:
22.84
4fvxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.35A 4fvyA-1h3jA:
0.0
4fvyB-1h3jA:
0.0		 4fvyA-1h3jA:
22.84
4fvyB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.33A 4fvyA-1h3jA:
0.0
4fvyB-1h3jA:
0.0		 4fvyA-1h3jA:
22.84
4fvyB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FVZ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 4fvzA-1h3jA:
0.0
4fvzB-1h3jA:
0.0		 4fvzA-1h3jA:
22.84
4fvzB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FW0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 4fw0A-1h3jA:
0.0
4fw0B-1h3jA:
0.0		 4fw0A-1h3jA:
22.84
4fw0B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4GQE_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4gqeA-1h3jA:
undetectable
4gqeB-1h3jA:
0.0		 4gqeA-1h3jA:
22.84
4gqeB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IMU_A_H4BA809_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.33A 4imuA-1h3jA:
1.5
4imuB-1h3jA:
0.0		 4imuA-1h3jA:
22.84
4imuB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 4jsfA-1h3jA:
1.5
4jsfB-1h3jA:
0.0		 4jsfA-1h3jA:
22.84
4jsfB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSF_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.34A 4jsfA-1h3jA:
1.5
4jsfB-1h3jA:
0.0		 4jsfA-1h3jA:
22.84
4jsfB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JSJ_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 4jsjA-1h3jA:
0.0
4jsjB-1h3jA:
0.0		 4jsjA-1h3jA:
22.84
4jsjB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5D_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 4k5dA-1h3jA:
0.0
4k5dB-1h3jA:
0.0		 4k5dA-1h3jA:
22.84
4k5dB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5E_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4k5eA-1h3jA:
0.0
4k5eB-1h3jA:
0.0		 4k5eA-1h3jA:
22.84
4k5eB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5F_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 4k5fA-1h3jA:
0.0
4k5fB-1h3jA:
0.0		 4k5fA-1h3jA:
22.84
4k5fB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K5G_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 4k5gA-1h3jA:
1.5
4k5gB-1h3jA:
0.0		 4k5gA-1h3jA:
22.84
4k5gB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 4kchA-1h3jA:
0.0
4kchB-1h3jA:
0.0		 4kchA-1h3jA:
22.84
4kchB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCH_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.22A 4kchA-1h3jA:
0.0
4kchB-1h3jA:
0.0		 4kchA-1h3jA:
22.84
4kchB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCI_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 4kciA-1h3jA:
undetectable
4kciB-1h3jA:
0.0		 4kciA-1h3jA:
22.84
4kciB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCK_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4kckA-1h3jA:
0.0
4kckB-1h3jA:
0.0		 4kckA-1h3jA:
22.84
4kckB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCM_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 4kcmA-1h3jA:
0.0
4kcmB-1h3jA:
0.0		 4kcmA-1h3jA:
22.84
4kcmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KCO_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.34A 4kcoA-1h3jA:
0.0
4kcoB-1h3jA:
0.0		 4kcoA-1h3jA:
22.84
4kcoB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.38A 4luxA-1h3jA:
0.0
4luxB-1h3jA:
0.0		 4luxA-1h3jA:
22.84
4luxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.39A 4luxA-1h3jA:
0.0
4luxB-1h3jA:
0.0		 4luxA-1h3jA:
22.84
4luxB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_A_HFGA803_1
(PROLINE--TRNA LIGASE)		 1kae HISTIDINOL
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 GLU A 326
THR A 141
HIS A 367
 HSO  A1001 ( 4.1A)
NAD  A1201 ( 4.1A)
HSO  A1001 (-3.5A)
 0.84A 4q15A-1kaeA:
3.0		 4q15A-1kaeA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Q15_B_HFGB803_1
(PROLINE--TRNA LIGASE)		 1kae HISTIDINOL
DEHYDROGENASE
(Escherichia
coli) 		3 / 3 GLU A 326
THR A 141
HIS A 367
 HSO  A1001 ( 4.1A)
NAD  A1201 ( 4.1A)
HSO  A1001 (-3.5A)
 0.82A 4q15B-1kaeA:
2.9		 4q15B-1kaeA:
21.08
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCH_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.35A 4uchA-1h3jA:
0.0
4uchB-1h3jA:
0.0		 4uchA-1h3jA:
22.59
4uchB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 4uh0A-1h3jA:
0.0
4uh0B-1h3jA:
0.0		 4uh0A-1h3jA:
22.84
4uh0B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH1_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4uh1A-1h3jA:
0.0
4uh1B-1h3jA:
0.0		 4uh1A-1h3jA:
22.84
4uh1B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH4_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4uh4A-1h3jA:
0.0
4uh4B-1h3jA:
0.0		 4uh4A-1h3jA:
22.84
4uh4B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.32A 4uh5A-1h3jA:
0.0
4uh5B-1h3jA:
0.0		 4uh5A-1h3jA:
22.59
4uh5B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH5_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.36A 4uh5A-1h3jA:
undetectable
4uh5B-1h3jA:
0.0		 4uh5A-1h3jA:
22.59
4uh5B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UH6_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.39A 4uh6A-1h3jA:
1.6
4uh6B-1h3jA:
0.0		 4uh6A-1h3jA:
22.59
4uh6B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 4upmA-1h3jA:
0.0
4upmB-1h3jA:
0.0		 4upmA-1h3jA:
22.84
4upmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPM_B_H4BB760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.30A 4upmA-1h3jA:
0.0
4upmB-1h3jA:
0.0		 4upmA-1h3jA:
22.84
4upmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPN_A_H4BA760_1
(NEURONAL NITRIC
OXIDE SYNTHASE)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 4upnA-1h3jA:
0.0
4upnB-1h3jA:
0.0		 4upnA-1h3jA:
22.84
4upnB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 4uppA-1h3jA:
0.0
4uppB-1h3jA:
0.0		 4uppA-1h3jA:
22.84
4uppB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UPP_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 4uppA-1h3jA:
0.0
4uppB-1h3jA:
0.0		 4uppA-1h3jA:
22.84
4uppB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4v3uA-1h3jA:
0.0
4v3uB-1h3jA:
0.0		 4v3uA-1h3jA:
22.59
4v3uB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.30A 4v3uA-1h3jA:
0.0
4v3uB-1h3jA:
0.0		 4v3uA-1h3jA:
22.59
4v3uB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_C_H4BC760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4v3uC-1h3jA:
0.0
4v3uD-1h3jA:
0.0		 4v3uC-1h3jA:
22.59
4v3uD-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3U_D_H4BD760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.28A 4v3uC-1h3jA:
0.0
4v3uD-1h3jA:
0.0		 4v3uC-1h3jA:
22.59
4v3uD-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3X_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 4v3xA-1h3jA:
0.0
4v3xB-1h3jA:
0.0		 4v3xA-1h3jA:
22.84
4v3xB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4V3Z_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.23A 4v3zA-1h3jA:
0.0
4v3zB-1h3jA:
0.0		 4v3zA-1h3jA:
22.84
4v3zB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ADI_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.38A 5adiA-1h3jA:
0.0
5adiB-1h3jA:
0.0		 5adiA-1h3jA:
22.59
5adiB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGL_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 5aglA-1h3jA:
0.0
5aglB-1h3jA:
0.0		 5aglA-1h3jA:
22.84
5aglB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGM_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 5agmA-1h3jA:
0.0
5agmB-1h3jA:
0.0		 5agmA-1h3jA:
22.84
5agmB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5AGO_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 5agoA-1h3jA:
0.0
5agoB-1h3jA:
0.0		 5agoA-1h3jA:
22.84
5agoB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVU_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.45A 5fvuA-1h3jA:
0.0
5fvuB-1h3jA:
1.3		 5fvuA-1h3jA:
22.59
5fvuB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVV_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.40A 5fvvA-1h3jA:
0.0
5fvvB-1h3jA:
0.0		 5fvvA-1h3jA:
22.59
5fvvB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVW_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.36A 5fvwA-1h3jA:
1.0
5fvwB-1h3jA:
0.0		 5fvwA-1h3jA:
22.59
5fvwB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FVX_B_H4BB760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.40A 5fvxA-1h3jA:
0.0
5fvxB-1h3jA:
1.4		 5fvxA-1h3jA:
22.59
5fvxB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5FW0_A_H4BA760_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 5fw0A-1h3jA:
0.0
5fw0B-1h3jA:
0.0		 5fw0A-1h3jA:
22.84
5fw0B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5M8R_B_MMSB514_1
(5,6-DIHYDROXYINDOLE-
2-CARBOXYLIC ACID
OXIDASE)		 1kae HISTIDINOL
DEHYDROGENASE
(Escherichia
coli) 		4 / 8 HIS A 262
SER A 347
HIS A 367
SER A 140
 ZN  A1101 ( 3.3A)
None
HSO  A1001 (-3.5A)
HSO  A1001 (-3.5A)
 1.00A 5m8rB-1kaeA:
undetectable		 5m8rB-1kaeA:
21.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OV9_B_CVIB603_0
(ACETYLCHOLINESTERASE)		 1kae HISTIDINOL
DEHYDROGENASE
(Escherichia
coli) 		4 / 7 TYR A 372
TYR A 374
GLN A 267
HIS A 327
 None
None
None
HSO  A1001 (-3.9A)
 1.34A 5ov9B-1kaeA:
undetectable		 5ov9B-1kaeA:
24.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UNU_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.35A 5unuA-1h3jA:
0.0
5unuB-1h3jA:
0.0		 5unuA-1h3jA:
22.84
5unuB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.36A 5uo0A-1h3jA:
1.0
5uo0B-1h3jA:
0.0		 5uo0A-1h3jA:
22.84
5uo0B-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.35A 5uo2A-1h3jA:
0.0
5uo2B-1h3jA:
1.1		 5uo2A-1h3jA:
22.59
5uo2B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.36A 5uo3A-1h3jA:
1.0
5uo3B-1h3jA:
undetectable		 5uo3A-1h3jA:
22.59
5uo3B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO3_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.37A 5uo3A-1h3jA:
1.0
5uo3B-1h3jA:
0.0		 5uo3A-1h3jA:
22.59
5uo3B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.28A 5uo4A-1h3jA:
0.0
5uo4B-1h3jA:
0.0		 5uo4A-1h3jA:
22.59
5uo4B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.37A 5uo4A-1h3jA:
0.0
5uo4B-1h3jA:
0.0		 5uo4A-1h3jA:
22.59
5uo4B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.32A 5uo5A-1h3jA:
undetectable
5uo5B-1h3jA:
0.0		 5uo5A-1h3jA:
22.59
5uo5B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.38A 5uo5A-1h3jA:
0.0
5uo5B-1h3jA:
0.0		 5uo5A-1h3jA:
22.59
5uo5B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.35A 5uo6A-1h3jA:
1.0
5uo6B-1h3jA:
1.1		 5uo6A-1h3jA:
22.59
5uo6B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO6_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.37A 5uo6A-1h3jA:
1.0
5uo6B-1h3jA:
1.1		 5uo6A-1h3jA:
22.59
5uo6B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 8 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.34A 5uo7A-1h3jA:
undetectable
5uo7B-1h3jA:
undetectable		 5uo7A-1h3jA:
22.59
5uo7B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5UO7_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.38A 5uo7A-1h3jA:
0.0
5uo7B-1h3jA:
1.1		 5uo7A-1h3jA:
22.59
5uo7B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUN_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.23A 5vunA-1h3jA:
0.0
5vunB-1h3jA:
0.0		 5vunA-1h3jA:
22.84
5vunB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUO_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.31A 5vuoA-1h3jA:
0.0
5vuoB-1h3jA:
0.0		 5vuoA-1h3jA:
22.84
5vuoB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUR_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.28A 5vurA-1h3jA:
0.0
5vurB-1h3jA:
1.2		 5vurA-1h3jA:
22.84
5vurB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUT_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 5vutA-1h3jA:
0.0
5vutB-1h3jA:
0.0		 5vutA-1h3jA:
22.84
5vutB-1h3jA:
22.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.28A 5vuvA-1h3jA:
0.0
5vuvB-1h3jA:
1.4		 5vuvA-1h3jA:
22.59
5vuvB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.37A 5vuvA-1h3jA:
0.0
5vuvB-1h3jA:
1.4		 5vuvA-1h3jA:
22.59
5vuvB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.30A 5vuwA-1h3jA:
0.0
5vuwB-1h3jA:
0.0		 5vuwA-1h3jA:
22.59
5vuwB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUW_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.36A 5vuwA-1h3jA:
0.0
5vuwB-1h3jA:
0.0		 5vuwA-1h3jA:
22.59
5vuwB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.27A 5vuxA-1h3jA:
0.0
5vuxB-1h3jA:
0.7		 5vuxA-1h3jA:
22.59
5vuxB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUX_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.35A 5vuxA-1h3jA:
0.0
5vuxB-1h3jA:
0.0		 5vuxA-1h3jA:
22.59
5vuxB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.26A 5vuyA-1h3jA:
0.0
5vuyB-1h3jA:
0.0		 5vuyA-1h3jA:
22.59
5vuyB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.26A 5vuyA-1h3jA:
0.0
5vuyB-1h3jA:
0.0		 5vuyA-1h3jA:
22.59
5vuyB-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.29A 5vv2A-1h3jA:
1.0
5vv2B-1h3jA:
0.0		 5vv2A-1h3jA:
22.59
5vv2B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.32A 5vv3A-1h3jA:
0.0
5vv3B-1h3jA:
0.0		 5vv3A-1h3jA:
22.59
5vv3B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.40A 5vv3A-1h3jA:
0.0
5vv3B-1h3jA:
0.0		 5vv3A-1h3jA:
22.59
5vv3B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 6 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.34A 5vv4A-1h3jA:
1.3
5vv4B-1h3jA:
0.0		 5vv4A-1h3jA:
22.59
5vv4B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.39A 5vv4A-1h3jA:
1.3
5vv4B-1h3jA:
0.0		 5vv4A-1h3jA:
22.59
5vv4B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.24A 5vv5A-1h3jA:
0.9
5vv5B-1h3jA:
0.0		 5vv5A-1h3jA:
22.59
5vv5B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VV5_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.38A 5vv5A-1h3jA:
0.9
5vv5B-1h3jA:
0.0		 5vv5A-1h3jA:
22.59
5vv5B-1h3jA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZW4_A_SAMA302_1
(PUTATIVE
O-METHYLTRANSFERASE
YRRM)		 2bkd FRAGILE X MENTAL
RETARDATION 1
PROTEIN
(Homo
sapiens) 		4 / 6 SER N  69
GLU N   7
ARG N   9
ASP N  46
 None
None
HSO  N  45 ( 3.9A)
HSO  N  45 ( 3.7A)
 1.30A 5zw4A-2bkdN:
undetectable		 5zw4A-2bkdN:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUS_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.25A 6ausA-1h3jA:
0.0
6ausB-1h3jA:
0.0		 6ausA-1h3jA:
12.42
6ausB-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUV_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.36A 6auvA-1h3jA:
0.0
6auvB-1h3jA:
0.0		 6auvA-1h3jA:
12.42
6auvB-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.29A 6auyA-1h3jA:
0.0
6auyB-1h3jA:
0.0		 6auyA-1h3jA:
12.42
6auyB-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUY_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.39A 6auyA-1h3jA:
0.0
6auyB-1h3jA:
0.0		 6auyA-1h3jA:
12.42
6auyB-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AUZ_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.39A 6auzA-1h3jA:
0.0
6auzB-1h3jA:
0.0		 6auzA-1h3jA:
12.42
6auzB-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.35A 6av0A-1h3jA:
0.0
6av0B-1h3jA:
0.0		 6av0A-1h3jA:
12.42
6av0B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV0_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.39A 6av0A-1h3jA:
0.0
6av0B-1h3jA:
0.0		 6av0A-1h3jA:
12.42
6av0B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.31A 6av2A-1h3jA:
0.0
6av2B-1h3jA:
0.7		 6av2A-1h3jA:
12.42
6av2B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV2_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.40A 6av2A-1h3jA:
0.0
6av2B-1h3jA:
0.7		 6av2A-1h3jA:
12.42
6av2B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.34A 6av3A-1h3jA:
0.0
6av3B-1h3jA:
0.0		 6av3A-1h3jA:
12.42
6av3B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV3_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.43A 6av3A-1h3jA:
0.0
6av3B-1h3jA:
1.2		 6av3A-1h3jA:
12.42
6av3B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.31A 6av4A-1h3jA:
0.0
6av4B-1h3jA:
0.0		 6av4A-1h3jA:
12.42
6av4B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV4_B_H4BB802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.40A 6av4A-1h3jA:
0.0
6av4B-1h3jA:
0.0		 6av4A-1h3jA:
12.42
6av4B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_A_H4BA802_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 MET A 268
VAL A 177
TRP A 258
PHE A 211
 None
None
None
HSO  A 183 ( 3.5A)
 1.36A 6av5A-1h3jA:
0.0
6av5B-1h3jA:
0.0		 6av5A-1h3jA:
12.42
6av5B-1h3jA:
12.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6AV5_B_H4BB803_1
(NITRIC OXIDE
SYNTHASE, BRAIN)		 1h3j PEROXIDASE
(Coprinopsis
cinerea) 		4 / 7 TRP A 258
PHE A 211
MET A 268
VAL A 177
 None
HSO  A 183 ( 3.5A)
None
None
 1.40A 6av5A-1h3jA:
0.0
6av5B-1h3jA:
0.0		 6av5A-1h3jA:
12.42
6av5B-1h3jA:
12.42