SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HO6'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2W1B_A_DXCA2034_0 (ACRIFLAVIN RESISTANCE PROTEIN B)	3sgz	HYDROXYACID OXIDASE 2 (Rattus norvegicus)	3 / 3	PHE A 199 SER A 105 LEU A 128	HO6 A 402 ( 4.8A) FMN A 401 (-2.8A) None	0.77A	2w1bA-3sgzA: undetectable	2w1bA-3sgzA: 16.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5BTF_G_GFNG101_1 (DNA GYRASE SUBUNIT A DNA GYRASE SUBUNIT B DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCAT GACC)	3sgz	HYDROXYACID OXIDASE 2 (Rattus norvegicus)	4 / 7	ARG A 282 ASP A 278 GLY A 249 THR A 158	FMN A 401 (-2.9A) FMN A 401 (-2.8A) None HO6 A 402 ( 4.6A)	1.04A	5btfA-3sgzA: undetectable 5btfC-3sgzA: undetectable 5btfD-3sgzA: undetectable	5btfA-3sgzA: 22.31 5btfC-3sgzA: 22.31 5btfD-3sgzA: 22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5HNZ_B_TA1B902_1 (TUBULIN BETA-2B CHAIN)	3sgz	HYDROXYACID OXIDASE 2 (Rattus norvegicus)	5 / 12	GLU A 88 LEU A 161 ASP A 167 SER A 109 THR A 158	None HO6 A 402 ( 4.5A) None None HO6 A 402 ( 4.6A)	1.35A	5hnzB-3sgzA: undetectable	5hnzB-3sgzA: 20.13

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2W1B_A_DXCA2034_0","ACRIFLAVIN RESISTANCE PROTEIN B","3sgz","HYDROXYACID OXIDASE 2","Rattus norvegicus",3,"PHE A 199;SER A 105;LEU A 128","HO6 A 402 ( 4.8A);FMN A 401 (-2.8A);None","0.77A","2w1bA-3sgzA:undetectable",null],["5BTF_G_GFNG101_1","DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT A;DNA GYRASE SUBUNIT B;DNA SUBSTRATE 24-MER TTACGTGCATAGTCATTCATGACC","3sgz","HYDROXYACID OXIDASE 2","Rattus norvegicus",4,"ARG A 282;ASP A 278;GLY A 249;THR A 158","FMN A 401 (-2.9A);FMN A 401 (-2.8A);None;HO6 A 402 ( 4.6A)","1.04A","5btfA-3sgzA:undetectable;5btfC-3sgzA:undetectable;5btfD-3sgzA:undetectable","2w1bA-3sgzA:16.01"],["5HNZ_B_TA1B902_1","TUBULIN BETA-2B CHAIN","3sgz","HYDROXYACID OXIDASE 2","Rattus norvegicus",5,"GLU A  88;LEU A 161;ASP A 167;SER A 109;THR A 158","None;HO6 A 402 ( 4.5A);None;None;HO6 A 402 ( 4.6A)","1.35A","5hnzB-3sgzA:undetectable","5btfA-3sgzA:22.31;5btfC-3sgzA:22.31;5btfD-3sgzA:22.59"]]