SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HHG'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2X45_A_HSMA1160_1 (ALLERGEN ARG R 1)	3e3c	L0044 (Escherichia coli)	4 / 6	TYR A 40 VAL A 54 TYR A 71 ASP A 35	HHG A 150 (-3.7A) None HHG A 150 (-4.6A) HHG A 150 (-3.5A)	1.34A	2x45A-3e3cA: 3.4	2x45A-3e3cA: 21.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_A_SORA1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e3c	L0044 (Escherichia coli)	4 / 7	ILE A 25 LEU A 24 GLY A 34 GLY A 33	None HHG A 150 (-4.9A) None None	0.78A	5a06A-3e3cA: undetectable	5a06A-3e3cA: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_B_SORB1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e3c	L0044 (Escherichia coli)	4 / 7	ILE A 25 LEU A 24 GLY A 34 GLY A 33	None HHG A 150 (-4.9A) None None	0.77A	5a06B-3e3cA: undetectable	5a06B-3e3cA: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_C_SORC1342_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e3c	L0044 (Escherichia coli)	4 / 7	ILE A 25 LEU A 24 GLY A 34 GLY A 33	None HHG A 150 (-4.9A) None None	0.77A	5a06C-3e3cA: undetectable	5a06C-3e3cA: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_E_SORE1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e3c	L0044 (Escherichia coli)	4 / 7	ILE A 25 LEU A 24 GLY A 34 GLY A 33	None HHG A 150 (-4.9A) None None	0.77A	5a06E-3e3cA: undetectable	5a06E-3e3cA: 17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5A06_F_SORF1341_0 (ALDOSE-ALDOSE OXIDOREDUCTASE)	3e3c	L0044 (Escherichia coli)	4 / 7	ILE A 25 LEU A 24 GLY A 34 GLY A 33	None HHG A 150 (-4.9A) None None	0.78A	5a06F-3e3cA: undetectable	5a06F-3e3cA: 17.21

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2X45_A_HSMA1160_1","ALLERGEN ARG R 1","3e3c","L0044","Escherichia coli",4,"TYR A  40;VAL A  54;TYR A  71;ASP A  35","HHG A 150 (-3.7A);None;HHG A 150 (-4.6A);HHG A 150 (-3.5A)","1.34A","2x45A-3e3cA:3.4",null],["5A06_A_SORA1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e3c","L0044","Escherichia coli",4,"ILE A  25;LEU A  24;GLY A  34;GLY A  33","None;HHG A 150 (-4.9A);None;None","0.78A","5a06A-3e3cA:undetectable","2x45A-3e3cA:21.05"],["5A06_B_SORB1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e3c","L0044","Escherichia coli",4,"ILE A  25;LEU A  24;GLY A  34;GLY A  33","None;HHG A 150 (-4.9A);None;None","0.77A","5a06B-3e3cA:undetectable","5a06A-3e3cA:17.21"],["5A06_C_SORC1342_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e3c","L0044","Escherichia coli",4,"ILE A  25;LEU A  24;GLY A  34;GLY A  33","None;HHG A 150 (-4.9A);None;None","0.77A","5a06C-3e3cA:undetectable","5a06B-3e3cA:17.21"],["5A06_E_SORE1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e3c","L0044","Escherichia coli",4,"ILE A  25;LEU A  24;GLY A  34;GLY A  33","None;HHG A 150 (-4.9A);None;None","0.77A","5a06E-3e3cA:undetectable","5a06C-3e3cA:17.21"],["5A06_F_SORF1341_0","ALDOSE-ALDOSE OXIDOREDUCTASE","3e3c","L0044","Escherichia coli",4,"ILE A  25;LEU A  24;GLY A  34;GLY A  33","None;HHG A 150 (-4.9A);None;None","0.78A","5a06F-3e3cA:undetectable","5a06E-3e3cA:17.21"]]