SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HEO'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2QHF_A_NCAA493_0
(CHORISMATE SYNTHASE)		 1fft UBIQUINOL OXIDASE
UBIQUINOL OXIDASE
(Escherichia
coli;
Escherichia
coli) 		5 / 11 ALA B 104
THR B 107
ILE B 100
ALA A 402
VAL A 403
 None
None
HEO  A1002 (-4.4A)
None
None
 1.09A 2qhfA-1fftB:
undetectable		 2qhfA-1fftB:
23.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_1
(PROTEASE RETROPEPSIN)		 1fft UBIQUINOL OXIDASE
(Escherichia
coli) 		5 / 12 ALA B 104
ILE A 354
GLY A 349
ALA A 356
ILE B 100
 None
None
None
HEO  A1002 (-3.3A)
HEO  A1002 (-4.4A)
 0.86A 2rkfA-1fftB:
undetectable		 2rkfA-1fftB:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2RKF_A_AB1A501_2
(PROTEASE RETROPEPSIN)		 1fft UBIQUINOL OXIDASE
(Escherichia
coli) 		5 / 12 ALA B 104
ILE A 354
GLY A 349
ALA A 356
ILE B 100
 None
None
None
HEO  A1002 (-3.3A)
HEO  A1002 (-4.4A)
 0.84A 2rkfB-1fftB:
undetectable		 2rkfB-1fftB:
16.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KO0_O_TFPO201_1
(PROTEIN S100-A4)		 1fft UBIQUINOL OXIDASE
(Escherichia
coli) 		4 / 8 GLY A 395
PHE A 457
GLY A 427
PHE A 430
 HEO  A1002 (-3.3A)
None
None
None
 0.79A 3ko0O-1fftA:
undetectable
3ko0Q-1fftA:
0.3		 3ko0O-1fftA:
8.57
3ko0Q-1fftA:
8.57