SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HDS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L1A_A_AB1A101_2
(MDR769 HIV-1
PROTEASE)		 1qd6 PROTEIN (OUTER
MEMBRANE
PHOSPHOLIPASE
(OMPLA))
(Escherichia
coli) 		4 / 6 ASN C 156
ASP C 184
GLY C 146
PRO C 116
 None
None
HDS  C 270 (-3.1A)
HDS  C 270 ( 4.6A)
 0.81A 4l1aB-1qd6C:
undetectable		 4l1aB-1qd6C:
19.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZBQ_A_ACTA605_0
(SERUM ALBUMIN)		 1qd6 PROTEIN (OUTER
MEMBRANE
PHOSPHOLIPASE
(OMPLA))
(Escherichia
coli) 		4 / 6 TYR C 140
HIS C 142
ARG C 157
ASN C 156
 None
HDS  C 270 (-3.9A)
None
None
 1.08A 4zbqA-1qd6C:
undetectable		 4zbqA-1qd6C:
15.59