SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HDD'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HXB_A_ROCA100_4
(HIV-1 PROTEASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 GLY A 107
ASP A 117
GLY A 120
THR A  68
 None
None
HDD  A 690 (-3.5A)
None
 0.83A 1hxbB-2xf2A:
undetectable		 1hxbB-2xf2A:
9.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TDR_A_MTXA170_1
(TELLUROMETHIONYL
DIHYDROFOLATE
REDUCTASE)		 5ir6 BD-TYPE QUINOL
OXIDASE SUBUNIT I
(Geobacillus
stearothermophil
us) 		5 / 12 ILE A 370
ALA A  25
LEU A  18
THR A 147
ARG A 381
 HEB  A 501 (-4.0A)
HEB  A 502 (-3.7A)
HDD  A 503 (-3.1A)
HDD  A 503 (-4.0A)
HDD  A 503 (-3.5A)
 1.09A 1tdrA-5ir6A:
undetectable		 1tdrA-5ir6A:
15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_E_MK1E902_4
(POL POLYPROTEIN)		 1ye9 CATALASE HPII
(Escherichia
coli) 		3 / 3 ARG E 411
VAL A 289
GLY E 399
 HDD  E 760 (-3.8A)
None
None
 0.62A 2avvE-1ye9E:
undetectable		 2avvE-1ye9E:
15.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_A_BEZA261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 8 HIS A  64
GLY A 120
ASN A 137
PHE A 150
 3TR  A 695 ( 2.7A)
HDD  A 690 (-3.5A)
3TR  A 695 ( 2.6A)
HDD  A 690 ( 3.5A)
 1.35A 3ccfA-2xf2A:
4.1		 3ccfA-2xf2A:
18.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3J7Z_A_ERYA9000_0
(23S RRNA
50S RIBOSOMAL
PROTEIN L22
ERMCL NASCENT CHAIN)		 5ir6 BD-TYPE QUINOL
OXIDASE SUBUNIT I
(Geobacillus
stearothermophil
us) 		3 / 3 LYS A 252
ILE A 146
PHE A 145
 HEB  A 501 (-3.3A)
HDD  A 503 ( 2.9A)
None
 0.99A 3j7zS-5ir6A:
0.5
3j7za-5ir6A:
undetectable		 3j7zS-5ir6A:
13.85
3j7za-5ir6A:
4.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_D_ROCD201_2
(HIV-1 PROTEASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 GLY A 107
ASP A 117
GLY A 120
THR A  68
 None
None
HDD  A 690 (-3.5A)
None
 0.87A 3k4vC-2xf2A:
undetectable		 3k4vC-2xf2A:
8.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 12 PHE A 149
GLY A 164
ALA A  98
GLY A  97
MET A 337
 None
HDD  A1880 ( 3.9A)
None
None
None
 0.95A 3v3oA-1sy7A:
undetectable		 3v3oA-1sy7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_A_T1CA404_1
(TETX2 PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 PHE A 121
GLY A 136
ALA A  70
GLY A  69
MET A 309
 None
HDD  A 690 (-3.9A)
None
None
None
 1.01A 3v3oA-2xf2A:
4.2		 3v3oA-2xf2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		5 / 12 PHE A 149
GLY A 164
ALA A  98
GLY A  97
MET A 337
 None
HDD  A1880 ( 3.9A)
None
None
None
 1.10A 3v3oB-1sy7A:
undetectable		 3v3oB-1sy7A:
19.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3O_B_T1CB405_1
(TETX2 PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 12 PHE A 121
GLY A 136
ALA A  70
GLY A  69
MET A 309
 None
HDD  A 690 (-3.9A)
None
None
None
 1.09A 3v3oB-2xf2A:
4.2		 3v3oB-2xf2A:
21.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4A6N_A_T1CA392_1
(TETX2 PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		5 / 11 PHE A 121
GLY A 136
ALA A  70
GLY A  69
MET A 309
 None
HDD  A 690 (-3.9A)
None
None
None
 1.19A 4a6nA-2xf2A:
3.7		 4a6nA-2xf2A:
21.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4AZT_A_SAMA1472_0
(METHYLTRANSFERASE
WBDD)		 5ir6 BD-TYPE QUINOL
OXIDASE SUBUNIT I
(Geobacillus
stearothermophil
us) 		5 / 12 TYR A 389
ALA A  90
GLU A 101
VAL A 149
ILE A 146
 None
None
HEB  A 502 (-3.0A)
HDD  A 503 ( 4.9A)
HDD  A 503 ( 2.9A)
 1.14A 4aztA-5ir6A:
undetectable		 4aztA-5ir6A:
22.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.50A 4jksA-1sy7A:
3.8		 4jksA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4jksA-2xf2A:
4.5		 4jksA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.48A 4jksB-1sy7A:
3.8		 4jksB-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 4 SER E 414
LEU E 408
TYR E 415
PRO A 215
 HDD  E 760 (-2.7A)
None
HDD  E 760 (-3.8A)
None
 1.49A 4jksB-1ye9E:
undetectable		 4jksB-1ye9E:
21.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKS_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.44A 4jksB-2xf2A:
4.5		 4jksB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.49A 4jkuA-1sy7A:
4.2		 4jkuA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JKU_A_ADNA500_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4jkuA-2xf2A:
5.1		 4jkuA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8C_B_ADNB401_2
(SUGAR KINASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4k8cB-2xf2A:
4.4		 4k8cB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_A_ADNA401_2
(SUGAR KINASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4k8kA-2xf2A:
4.4		 4k8kA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.49A 4k8kB-1sy7A:
3.8		 4k8kB-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4K8K_B_ADNB403_2
(SUGAR KINASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4k8kB-2xf2A:
4.6		 4k8kB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.50A 4kalA-1sy7A:
3.8		 4kalA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4kalA-2xf2A:
4.5		 4kalA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.48A 4kalB-1sy7A:
3.8		 4kalB-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KAL_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.44A 4kalB-2xf2A:
4.5		 4kalB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 6 GLY A 200
ASP A 197
PRO E 393
ARG E 411
 HDD  E 760 (-3.8A)
None
None
HDD  E 760 (-3.8A)
 1.10A 4lajA-1ye9A:
undetectable
4lajB-1ye9A:
undetectable		 4lajA-1ye9A:
19.84
4lajB-1ye9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 6 GLY A 273
ASP A 197
PRO E 393
ARG E 411
 None
None
None
HDD  E 760 (-3.8A)
 1.06A 4lajA-1ye9A:
undetectable
4lajB-1ye9A:
undetectable		 4lajA-1ye9A:
19.84
4lajB-1ye9A:
19.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 GLY A 136
ASP A 133
PRO A 329
ARG A 347
 HDD  A 690 (-3.9A)
None
None
HDD  A 690 (-3.6A)
 1.17A 4lajA-2xf2A:
undetectable
4lajB-2xf2A:
undetectable		 4lajA-2xf2A:
20.41
4lajB-2xf2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LAJ_B_ACAB512_1
(HIV-1 YU2 GP120
ENVELOPE
GLYCOPROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 GLY A 209
ASP A 133
PRO A 329
ARG A 347
 None
None
None
HDD  A 690 (-3.6A)
 0.99A 4lajA-2xf2A:
undetectable
4lajB-2xf2A:
undetectable		 4lajA-2xf2A:
20.41
4lajB-2xf2A:
20.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 4 SER A 378
LEU A 372
TYR A 379
PRO A 179
 HDD  A1880 ( 2.7A)
None
HDD  A1880 ( 4.0A)
None
 1.50A 4lcaA-1sy7A:
3.8		 4lcaA-1sy7A:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_A_ADNA401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.46A 4lcaA-2xf2A:
4.5		 4lcaA-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LCA_B_ADNB401_2
(PROBABLE SUGAR
KINASE PROTEIN)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 4 SER A 350
LEU A 344
TYR A 351
PRO A 151
 HDD  A 690 (-2.8A)
None
HDD  A 690 (-3.7A)
None
 1.45A 4lcaB-2xf2A:
4.5		 4lcaB-2xf2A:
20.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 6 LEU E 408
ASP E 405
TYR E 415
LEU E 412
 None
None
HDD  E 760 (-3.8A)
None
 1.04A 4wozA-1ye9E:
undetectable
4wozB-1ye9E:
undetectable		 4wozA-1ye9E:
20.45
4wozB-1ye9E:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_B_MN9B401_0
(N-ACETYLNEURAMINATE
LYASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 6 LEU A 344
ASP A 341
TYR A 351
LEU A 348
 None
None
HDD  A 690 (-3.7A)
None
 0.94A 4wozA-2xf2A:
undetectable
4wozB-2xf2A:
undetectable		 4wozA-2xf2A:
17.91
4wozB-2xf2A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4WOZ_F_MN9F401_0
(N-ACETYLNEURAMINATE
LYASE)		 2xf2 CATALASE
(Penicillium
janthinellum) 		4 / 5 LEU A 344
ASP A 341
TYR A 351
LEU A 348
 None
None
HDD  A 690 (-3.7A)
None
 0.98A 4wozF-2xf2A:
undetectable
4wozH-2xf2A:
undetectable		 4wozF-2xf2A:
17.91
4wozH-2xf2A:
17.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A5Z_C_WJZC304_0
(BETA-LACTAMASE NDM-1)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 7 MET A 233
HIS A  92
GLY A 164
ASN A 165
 None
HEM  A1883 ( 3.5A)
HDD  A1880 ( 3.9A)
HDD  A1880 ( 3.1A)
 1.34A 5a5zC-1sy7A:
undetectable		 5a5zC-1sy7A:
16.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NZY_A_CE3A1103_1
(DNA CROSS-LINK
REPAIR 1A PROTEIN)		 1sy7 CATALASE 1
(Neurospora
crassa) 		4 / 8 TYR A 379
ASP A 369
VAL A 163
GLY A 164
 HDD  A1880 ( 4.0A)
None
HDD  A1880 ( 4.8A)
HDD  A1880 ( 3.9A)
 0.88A 5nzyA-1sy7A:
undetectable		 5nzyA-1sy7A:
17.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXQ_A_NIZA808_1
(CATALASE-PEROXIDASE)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 8 ARG E 422
GLY E 424
GLN E 419
LEU E 423
 HDD  E 760 ( 4.5A)
None
HDD  E 760 (-3.9A)
None
 0.95A 5sxqA-1ye9E:
undetectable		 5sxqA-1ye9E:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_A_NIZA807_1
(CATALASE-PEROXIDASE)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 8 ARG E 422
GLY E 424
GLN E 419
LEU E 423
 HDD  E 760 ( 4.5A)
None
HDD  E 760 (-3.9A)
None
 0.89A 5sxtA-1ye9E:
undetectable		 5sxtA-1ye9E:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SXT_B_NIZB808_1
(CATALASE-PEROXIDASE)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 8 ARG E 422
GLY E 424
GLN E 419
LEU E 423
 HDD  E 760 ( 4.5A)
None
HDD  E 760 (-3.9A)
None
 0.89A 5sxtB-1ye9E:
undetectable		 5sxtB-1ye9E:
17.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5SYJ_B_NIZB809_1
(CATALASE-PEROXIDASE)		 1ye9 CATALASE HPII
(Escherichia
coli) 		4 / 8 ARG E 422
GLY E 424
GLN E 419
LEU E 423
 HDD  E 760 ( 4.5A)
None
HDD  E 760 (-3.9A)
None
 0.85A 5syjB-1ye9E:
undetectable		 5syjB-1ye9E:
18.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6J21_A_GBQA1201_0
(SUBSTANCE-P
RECEPTOR,ENDOLYSIN)		 1ye9 CATALASE HPII
(Escherichia
coli) 		5 / 12 ASN A 252
VAL A 127
HIS A 236
PHE A 217
PHE A 239
 None
HDD  E 760 (-4.3A)
None
None
None
 1.32A 6j21A-1ye9A:
undetectable		 6j21A-1ye9A:
18.29