SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HCB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NVK_J_SAMJ228_0
(FIBRILLARIN-LIKE
RRNA/TRNA
2'-O-METHYLTRANSFERA
SE
NOP5/NOP56 RELATED
PROTEIN)		 3ezx MONOMETHYLAMINE
CORRINOID PROTEIN 1
(Methanosarcina
barkeri) 		5 / 12 GLU A 203
GLY A 184
ALA A 202
ALA A 154
VAL A 188
 None
HCB  A   1 (-3.6A)
HCB  A   1 ( 3.7A)
None
None
 1.16A 3nvkF-3ezxA:
2.6
3nvkJ-3ezxA:
3.0		 3nvkF-3ezxA:
21.60
3nvkJ-3ezxA:
22.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5V0V_A_8QPA613_1
(SERUM ALBUMIN)		 3ezx MONOMETHYLAMINE
CORRINOID PROTEIN 1
(Methanosarcina
barkeri) 		4 / 8 ALA A 205
VAL A 113
THR A 201
GLY A 109
 HCB  A   1 (-4.8A)
None
None
HCB  A   1 ( 3.7A)
 1.01A 5v0vA-3ezxA:
2.6		 5v0vA-3ezxA:
17.16