SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HC8'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A25_A_SAMA279_0
(UNCHARACTERIZED
PROTEIN PH0793)		 3hrr AFLATOXIN
BIOSYNTHESIS
POLYKETIDE SYNTHASE
(Aspergillus
parasiticus) 		5 / 12 ASN A1568
PHE A1357
GLY A1344
HIS A1345
ASP A1504
 None
None
None
HC8  A4000 (-3.5A)
None
 1.05A 3a25A-3hrrA:
undetectable		 3a25A-3hrrA:
23.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_A_MIYA2001_1
(TETX2 PROTEIN)		 3hrr AFLATOXIN
BIOSYNTHESIS
POLYKETIDE SYNTHASE
(Aspergillus
parasiticus) 		5 / 11 GLN A1547
HIS A1345
PHE A1526
GLY A1529
ASN A1582
 None
HC8  A4000 (-3.5A)
None
None
None
 1.46A 3v3nA-3hrrA:
undetectable		 3v3nA-3hrrA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V3N_D_MIYD2001_1
(TETX2 PROTEIN)		 3hrr AFLATOXIN
BIOSYNTHESIS
POLYKETIDE SYNTHASE
(Aspergillus
parasiticus) 		5 / 11 GLN A1547
HIS A1345
PHE A1526
GLY A1529
ASN A1582
 None
HC8  A4000 (-3.5A)
None
None
None
 1.46A 3v3nD-3hrrA:
undetectable		 3v3nD-3hrrA:
22.72