SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HAH'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q63_A_1UNA1001_4
(PROTEASE RETROPEPSIN)		 3emq ENDO-1,4-BETA-XYLANA
SE
(Paenibacillus
barcinonensis) 		3 / 3 ASP A 130
ASN A 133
THR A  89
 None
HAH  A1000 (-3.4A)
None
 0.80A 2q63B-3emqA:
undetectable		 2q63B-3emqA:
16.23
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_A_SAMA238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3emq ENDO-1,4-BETA-XYLANA
SE
(Paenibacillus
barcinonensis) 		3 / 3 TYR A 297
GLU A 241
ASP A 178
 None
HAH  A1000 (-3.0A)
None
 0.80A 3bxoA-3emqA:
undetectable		 3bxoA-3emqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BXO_B_SAMB238_1
(N,N-DIMETHYLTRANSFER
ASE)		 3emq ENDO-1,4-BETA-XYLANA
SE
(Paenibacillus
barcinonensis) 		3 / 3 TYR A 297
GLU A 241
ASP A 178
 None
HAH  A1000 (-3.0A)
None
 0.79A 3bxoB-3emqA:
undetectable		 3bxoB-3emqA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_A_SAMA501_1
(MNMC2)		 3emq ENDO-1,4-BETA-XYLANA
SE
(Paenibacillus
barcinonensis) 		4 / 6 GLU A  44
ASP A 301
ASN A 296
GLU A  30
 HAH  A1000 ( 4.9A)
None
None
None
 1.28A 3vywA-3emqA:
undetectable		 3vywA-3emqA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VYW_D_SAMD401_1
(MNMC2)		 3emq ENDO-1,4-BETA-XYLANA
SE
(Paenibacillus
barcinonensis) 		4 / 5 GLU A  44
ASP A 301
ASN A 296
GLU A  30
 HAH  A1000 ( 4.9A)
None
None
None
 1.28A 3vywD-3emqA:
undetectable		 3vywD-3emqA:
22.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O0O_A_URFA303_1
(RRNA N-GLYCOSIDASE)		 3emq ENDO-1,4-BETA-XYLANA
SE
(Paenibacillus
barcinonensis) 		4 / 5 TYR A 179
ASN A 177
TYR A 176
ILE A 190
 HAH  A1000 (-3.9A)
None
None
None
 1.31A 4o0oA-3emqA:
undetectable		 4o0oA-3emqA:
21.69