SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'HAE'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1FWE_C_HAEC989_1
(UREASE)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		6 / 6 HIS B 136
HIS B 138
HIS B 221
HIS B 248
HIS B 274
ASP B 362
 NI  B3002 (-3.5A)
NI  B3002 (-3.3A)
KCX  B 219 (-4.0A)
NI  B3001 ( 3.4A)
NI  B3001 ( 3.5A)
HAE  B 800 ( 2.5A)
 0.26A 1fweC-1e9yB:
60.2		 1fweC-1e9yB:
61.86
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_A_HAEA874_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 472 (-3.1A)
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.58A 1os2A-3ba0A:
28.6		 1os2A-3ba0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1OS2_D_HAED574_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.40A 1os2D-3ba0A:
28.6		 1os2D-3ba0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1R55_A_097A518_1
(ADAM 33)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 10 THR A 215
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.67A 1r55A-3ba0A:
9.3		 1r55A-3ba0A:
18.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTT_A_HAEA1265_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.45A 1uttA-3ba0A:
28.4		 1uttA-3ba0A:
99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_A_HAEA1267_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.40A 1utzA-3ba0A:
28.2		 1utzA-3ba0A:
99.37
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1UTZ_B_HAEB1266_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.44A 1utzB-3ba0A:
28.2		 1utzB-3ba0A:
99.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 1v54A-3ba0A:
undetectable		 1v54A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V54_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 1v54N-3ba0A:
undetectable		 1v54N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_A_CUA517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 1v55A-3ba0A:
undetectable		 1v55A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_N_CUN517_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 1v55N-3ba0A:
undetectable		 1v55N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1W76_B_GNTB1538_1
(ACETYLCHOLINESTERASE)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 ASP B 250
GLY B 279
GLY B 280
PHE B 334
HIS B 322
 None
HAE  B 800 ( 4.5A)
None
None
None
 1.12A 1w76B-1e9yB:
undetectable		 1w76B-1e9yB:
20.35
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1Y93_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		6 / 6 ILE A 180
HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
ZN  A 472 (-3.1A)
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.80A 1y93A-3ba0A:
28.4		 1y93A-3ba0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 2dyrA-3ba0A:
undetectable		 2dyrA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYR_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 2dyrN-3ba0A:
undetectable		 2dyrN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 2dysA-3ba0A:
undetectable		 2dysA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.71A 2eijA-3ba0A:
undetectable		 2eijA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIJ_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 2eijN-3ba0A:
undetectable		 2eijN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 2eikA-3ba0A:
undetectable		 2eikA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 2eikN-3ba0A:
undetectable		 2eikN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 2eilA-3ba0A:
undetectable		 2eilA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 2eilN-3ba0A:
undetectable		 2eilN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 2eimA-3ba0A:
undetectable		 2eimA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 2eimN-3ba0A:
undetectable		 2eimN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.71A 2einA-3ba0A:
undetectable		 2einA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.68A 2einN-3ba0A:
undetectable		 2einN-3ba0A:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2HU6_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.41A 2hu6A-3ba0A:
28.4		 2hu6A-3ba0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		6 / 9 LEU A 181
THR A 215
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
None
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.79A 2jihA-3ba0A:
9.6		 2jihA-3ba0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_B_097B1001_1
(ADAMTS-1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		6 / 8 LEU A 181
THR A 215
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
None
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.79A 2jihB-3ba0A:
9.7		 2jihB-3ba0A:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_A_SAMA302_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		3 / 3 THR B 251
ASP B 362
SER B 360
 None
HAE  B 800 ( 2.5A)
None
 0.84A 2nxeA-1e9yB:
undetectable		 2nxeA-1e9yB:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NXE_B_SAMB303_1
(RIBOSOMAL PROTEIN
L11
METHYLTRANSFERASE)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		3 / 3 THR B 251
ASP B 362
SER B 360
 None
HAE  B 800 ( 2.5A)
None
 0.78A 2nxeB-1e9yB:
undetectable		 2nxeB-1e9yB:
20.35
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_A_HAEA502_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 6 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 472 (-3.1A)
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.68A 2ow9A-3ba0A:
26.6		 2ow9A-3ba0A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OW9_B_HAEB502_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.34A 2ow9B-3ba0A:
26.3		 2ow9B-3ba0A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_C_HAEC3001_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.34A 2ozrC-3ba0A:
26.8		 2ozrC-3ba0A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_D_HAED3002_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.31A 2ozrD-3ba0A:
27.0		 2ozrD-3ba0A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_E_HAEE3003_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.42A 2ozrE-3ba0A:
26.2		 2ozrE-3ba0A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OZR_F_HAEF3004_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 218
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.35A 2ozrF-3ba0A:
26.1		 2ozrF-3ba0A:
28.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 2y69A-3ba0A:
undetectable		 2y69A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 2y69N-3ba0A:
undetectable		 2y69N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y7K_A_SALA1302_1
(LYSR-TYPE REGULATORY
PROTEIN)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 GLY B 279
GLY B 281
PHE B 334
HIS B 322
HIS B 221
 HAE  B 800 ( 4.5A)
None
None
None
KCX  B 219 (-4.0A)
 1.44A 2y7kA-1e9yB:
0.0		 2y7kA-1e9yB:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.78A 2zxwA-3ba0A:
undetectable		 2zxwA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2ZXW_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 2zxwN-3ba0A:
undetectable		 2zxwN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3A27_A_SAMA250_1
(UNCHARACTERIZED
PROTEIN MJ1557)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		3 / 3 MET B 366
GLU B 222
ASN B 253
 HAE  B 800 ( 4.6A)
None
None
 0.92A 3a27A-1e9yB:
undetectable		 3a27A-1e9yB:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.76A 3abkA-3ba0A:
undetectable		 3abkA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABK_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 3abkN-3ba0A:
undetectable		 3abkN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 3ablA-3ba0A:
undetectable		 3ablA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABL_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.78A 3ablN-3ba0A:
undetectable		 3ablN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3abmA-3ba0A:
undetectable		 3abmA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 3abmN-3ba0A:
undetectable		 3abmN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 3ag1A-3ba0A:
undetectable		 3ag1A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG1_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3ag1N-3ba0A:
undetectable		 3ag1N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3ag2A-3ba0A:
undetectable		 3ag2A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG2_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3ag2N-3ba0A:
undetectable		 3ag2N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 3ag3A-3ba0A:
undetectable		 3ag3A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AG3_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 3ag3N-3ba0A:
undetectable		 3ag3N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3asnA-3ba0A:
undetectable		 3asnA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 3asnN-3ba0A:
undetectable		 3asnN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_A_CUA517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 3asoA-3ba0A:
undetectable		 3asoA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_N_CUN517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 3asoN-3ba0A:
undetectable		 3asoN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BVD_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.68A 3bvdA-3ba0A:
undetectable		 3bvdA-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_A_CUA1023_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 3dtuA-3ba0A:
undetectable		 3dtuA-3ba0A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DTU_C_CUC569_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 3dtuC-3ba0A:
undetectable		 3dtuC-3ba0A:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EKY_A_DR7A100_2
(PROTEASE)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 9 ASP B 362
ILE B 137
GLY B 159
ILE B 172
ILE B 140
 HAE  B 800 ( 2.5A)
None
None
KCX  B 219 ( 4.4A)
None
 1.27A 3ekyB-1e9yB:
undetectable		 3ekyB-1e9yB:
11.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_A_097A801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		6 / 9 LEU A 181
THR A 215
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
None
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.77A 3hy7A-3ba0A:
9.9		 3hy7A-3ba0A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3HY7_B_097B801_1
(A DISINTEGRIN AND
METALLOPROTEINASE
WITH THROMBOSPONDIN
MOTIFS 5)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		6 / 9 LEU A 181
THR A 215
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
None
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.76A 3hy7B-3ba0A:
9.8		 3hy7B-3ba0A:
18.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3KEC_A_HAEA272_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 5 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.36A 3kecA-3ba0A:
26.5		 3kecA-3ba0A:
28.70
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIK_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 472 (-3.1A)
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.73A 3likA-3ba0A:
28.1		 3likA-3ba0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LIL_A_HAEA302_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.42A 3lilA-3ba0A:
28.1		 3lilA-3ba0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LJG_A_HAEA301_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 5 ILE A 180
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.65A 3ljgA-3ba0A:
28.3		 3ljgA-3ba0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3LKA_A_HAEA269_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 472 (-3.1A)
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.68A 3lkaA-3ba0A:
28.4		 3lkaA-3ba0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S33_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3s33A-3ba0A:
undetectable		 3s33A-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S38_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.70A 3s38A-3ba0A:
undetectable		 3s38A-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S39_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 3s39A-3ba0A:
undetectable		 3s39A-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3A_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3s3aA-3ba0A:
undetectable		 3s3aA-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3B_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.77A 3s3bA-3ba0A:
undetectable		 3s3bA-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3C_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.77A 3s3cA-3ba0A:
undetectable		 3s3cA-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3S3D_A_CUA803_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3s3dA-3ba0A:
undetectable		 3s3dA-3ba0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.70A 3wg7A-3ba0A:
undetectable		 3wg7A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 3wg7N-3ba0A:
undetectable		 3wg7N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_A_CUA604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 3x2qA-3ba0A:
undetectable		 3x2qA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.68A 3x2qN-3ba0A:
undetectable		 3x2qN-3ba0A:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_A_HAEA1273_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 6 HIS A 183
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 472 (-3.1A)
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.65A 4a7bA-3ba0A:
27.0		 4a7bA-3ba0A:
31.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4A7B_B_HAEB1270_1
(COLLAGENASE 3)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 5 HIS A 183
HIS A 218
GLU A 219
HIS A 222
 ZN  A 472 (-3.1A)
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
 0.59A 4a7bB-3ba0A:
26.6		 4a7bB-3ba0A:
31.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4H9M_A_HAEA929_1
(UREASE)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 5 HIS B 136
HIS B 221
HIS B 248
HIS B 274
ASP B 362
 NI  B3002 (-3.5A)
KCX  B 219 (-4.0A)
NI  B3001 ( 3.4A)
NI  B3001 ( 3.5A)
HAE  B 800 ( 2.5A)
 0.29A 4h9mA-1e9yB:
58.1		 4h9mA-1e9yB:
40.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.00A 4qvlK-1e9yB:
undetectable
4qvlL-1e9yB:
undetectable		 4qvlK-1e9yB:
17.51
4qvlL-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVL_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.99A 4qvlY-1e9yB:
undetectable
4qvlZ-1e9yB:
undetectable		 4qvlY-1e9yB:
17.51
4qvlZ-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 9 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.01A 4qvmK-1e9yB:
undetectable
4qvmL-1e9yB:
undetectable		 4qvmK-1e9yB:
16.97
4qvmL-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVM_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.01A 4qvmY-1e9yB:
undetectable
4qvmZ-1e9yB:
undetectable		 4qvmY-1e9yB:
16.97
4qvmZ-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.02A 4qvpK-1e9yB:
undetectable
4qvpL-1e9yB:
undetectable		 4qvpK-1e9yB:
17.15
4qvpL-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVP_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.01A 4qvpY-1e9yB:
undetectable
4qvpZ-1e9yB:
undetectable		 4qvpY-1e9yB:
17.15
4qvpZ-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 THR B 272
GLY B 281
GLY B 280
ASP B 362
 None
None
None
HAE  B 800 ( 2.5A)
 0.84A 4qvvK-1e9yB:
undetectable
4qvvL-1e9yB:
undetectable		 4qvvK-1e9yB:
17.51
4qvvL-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVV_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		4 / 8 THR B 272
GLY B 281
GLY B 280
ASP B 362
 None
None
None
HAE  B 800 ( 2.5A)
 0.84A 4qvvY-1e9yB:
undetectable
4qvvZ-1e9yB:
undetectable		 4qvvY-1e9yB:
17.51
4qvvZ-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.98A 4qvwK-1e9yB:
undetectable
4qvwL-1e9yB:
undetectable		 4qvwK-1e9yB:
17.51
4qvwL-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QVW_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.98A 4qvwY-1e9yB:
undetectable
4qvwZ-1e9yB:
undetectable		 4qvwY-1e9yB:
17.51
4qvwZ-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.01A 4qw1K-1e9yB:
undetectable
4qw1L-1e9yB:
undetectable		 4qw1K-1e9yB:
17.33
4qw1L-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW1_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.01A 4qw1Y-1e9yB:
undetectable
4qw1Z-1e9yB:
undetectable		 4qw1Y-1e9yB:
17.33
4qw1Z-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 1.00A 4qw3K-1e9yB:
undetectable
4qw3L-1e9yB:
undetectable		 4qw3K-1e9yB:
17.51
4qw3L-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4QW3_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 10 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.99A 4qw3Y-1e9yB:
undetectable
4qw3Z-1e9yB:
undetectable		 4qw3Y-1e9yB:
17.51
4qw3Z-1e9yB:
17.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4UBP_C_HAEC800_1
(PROTEIN (UREASE
(CHAIN C)))		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		6 / 6 HIS B 136
HIS B 138
HIS B 221
HIS B 248
HIS B 274
ASP B 362
 NI  B3002 (-3.5A)
NI  B3002 (-3.3A)
KCX  B 219 (-4.0A)
NI  B3001 ( 3.4A)
NI  B3001 ( 3.5A)
HAE  B 800 ( 2.5A)
 0.27A 4ubpC-1e9yB:
51.0		 4ubpC-1e9yB:
61.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 5b1aA-3ba0A:
undetectable		 5b1aA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 5b1aN-3ba0A:
undetectable		 5b1aN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.71A 5b1bA-3ba0A:
undetectable		 5b1bA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 5b1bN-3ba0A:
undetectable		 5b1bN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5b3sA-3ba0A:
undetectable		 5b3sA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5b3sN-3ba0A:
undetectable		 5b3sN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.99A 5bxnK-1e9yB:
undetectable
5bxnL-1e9yB:
undetectable		 5bxnK-1e9yB:
17.51
5bxnL-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BXN_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 11 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.98A 5bxnY-1e9yB:
undetectable
5bxnZ-1e9yB:
undetectable		 5bxnY-1e9yB:
17.51
5bxnZ-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_K_BO2K301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 9 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.99A 5d0xK-1e9yB:
undetectable
5d0xL-1e9yB:
undetectable		 5d0xK-1e9yB:
17.52
5d0xL-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5D0X_Y_BO2Y301_1
(PROTEASOME SUBUNIT
BETA TYPE-5
PROTEASOME SUBUNIT
BETA TYPE-6)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		5 / 9 THR B 272
ALA B 298
GLY B 281
GLY B 280
ASP B 362
 None
None
None
None
HAE  B 800 ( 2.5A)
 0.99A 5d0xY-1e9yB:
undetectable
5d0xZ-1e9yB:
undetectable		 5d0xY-1e9yB:
17.52
5d0xZ-1e9yB:
17.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.71A 5iy5A-3ba0A:
undetectable		 5iy5A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5iy5N-3ba0A:
undetectable		 5iy5N-3ba0A:
20.45
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5J_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		4 / 4 HIS A 218
GLU A 219
HIS A 222
HIS A 228
 ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.41A 5n5jA-3ba0A:
28.4		 5n5jA-3ba0A:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5N5K_A_HAEA306_1
(MACROPHAGE
METALLOELASTASE)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		5 / 5 ILE A 180
HIS A 218
GLU A 219
HIS A 222
HIS A 228
 None
ZN  A 471 (-4.0A)
ZN  A 471 ( 3.2A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-3.7A)
 0.73A 5n5kA-3ba0A:
28.0		 5n5kA-3ba0A:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NCD_D_ACTD301_0
(PEPTIDOGLYCAN
N-ACETYLGLUCOSAMINE
DEACETYLASE)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		4 / 4 ASP B 362
HIS B 274
HIS B 248
HIS B 138
 HAE  B 800 ( 2.5A)
NI  B3001 ( 3.5A)
NI  B3001 ( 3.4A)
NI  B3002 (-3.3A)
 1.49A 5ncdD-1e9yB:
2.2		 5ncdD-1e9yB:
19.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.68A 5w97a-3ba0A:
undetectable		 5w97a-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 5waua-3ba0A:
undetectable		 5waua-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5x19A-3ba0A:
undetectable		 5x19A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.68A 5x19N-3ba0A:
undetectable		 5x19N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.68A 5x1bA-3ba0A:
undetectable		 5x1bA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1B_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.65A 5x1bN-3ba0A:
undetectable		 5x1bN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.71A 5x1fA-3ba0A:
undetectable		 5x1fA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.63A 5x1fN-3ba0A:
undetectable		 5x1fN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 5xdqA-3ba0A:
undetectable		 5xdqA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 5xdqN-3ba0A:
undetectable		 5xdqN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.70A 5xdxA-3ba0A:
undetectable		 5xdxA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.69A 5xdxN-3ba0A:
undetectable		 5xdxN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.76A 5z84A-3ba0A:
undetectable		 5z84A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 5z84N-3ba0A:
undetectable		 5z84N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.76A 5z85A-3ba0A:
undetectable		 5z85A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5z85N-3ba0A:
undetectable		 5z85N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5z86A-3ba0A:
undetectable		 5z86A-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 5z86N-3ba0A:
undetectable		 5z86N-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 5zcoA-3ba0A:
undetectable		 5zcoA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.70A 5zcoN-3ba0A:
undetectable		 5zcoN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 5zcpA-3ba0A:
undetectable		 5zcpA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_N_CUN604_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.75A 5zcpN-3ba0A:
undetectable		 5zcpN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5zcqA-3ba0A:
undetectable		 5zcqA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 5zcqN-3ba0A:
undetectable		 5zcqN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECT_A_SAMA1300_1
(STIE PROTEIN)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		4 / 5 THR B 269
ARG B 520
THR B 135
ASP B 362
 None
None
None
HAE  B 800 ( 2.5A)
 1.32A 6ectA-1e9yB:
1.3		 6ectA-1e9yB:
19.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6ECX_A_SAMA1301_1
(STIE PROTEIN)		 1e9y UREASE SUBUNIT BETA
(Helicobacter
pylori) 		4 / 5 THR B 269
ARG B 520
THR B 135
ASP B 362
 None
None
None
HAE  B 800 ( 2.5A)
 1.40A 6ecxA-1e9yB:
undetectable		 6ecxA-1e9yB:
18.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.67A 6hu9a-3ba0A:
undetectable		 6hu9a-3ba0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6HU9_M_CUM601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.69A 6hu9m-3ba0A:
undetectable		 6hu9m-3ba0A:
22.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.74A 6nknA-3ba0A:
undetectable		 6nknA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NKN_N_CUN602_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 6nknN-3ba0A:
undetectable		 6nknN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_A_CUA603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.69A 6nmfA-3ba0A:
undetectable		 6nmfA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMF_N_CUN603_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.69A 6nmfN-3ba0A:
undetectable		 6nmfN-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_A_CUA601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.73A 6nmpA-3ba0A:
undetectable		 6nmpA-3ba0A:
20.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6NMP_N_CUN601_0
(CYTOCHROME C OXIDASE
SUBUNIT 1)		 3ba0 MACROPHAGE
METALLOELASTASE
(Homo
sapiens) 		3 / 3 HIS A 228
HIS A 222
HIS A 218
 ZN  A 471 (-3.7A)
HAE  A 477 ( 3.1A)
ZN  A 471 (-4.0A)
 0.72A 6nmpN-3ba0A:
undetectable		 6nmpN-3ba0A:
20.45