SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'H35'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1MRJ_A_ADNA300_1
(ALPHA-TRICHOSANTHIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 8 GLY A 113
ILE A 160
SER A 164
GLU A 165
ARG A 168
 None
H35  A 305 ( 4.5A)
None
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.47A 1mrjA-4jkxA:
32.3		 1mrjA-4jkxA:
37.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3LD6_A_KKKA602_1
(LANOSTEROL 14-ALPHA
DEMETHYLASE)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 12 TYR A  17
PHE A 186
GLY A 183
ILE A 158
ILE A 160
 None
None
None
None
H35  A 305 ( 4.5A)
 1.41A 3ld6A-4jkxA:
undetectable		 3ld6A-4jkxA:
18.84
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3U6T_A_KANA4699_1
(RIBOSOME
INACTIVATING PROTEIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 10 TYR A  76
ASN A 112
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
NAG  A 302 (-1.9A)
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 1.17A 3u6tA-4jkxA:
32.4		 3u6tA-4jkxA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
4YP2_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 9 TYR A  76
GLY A 113
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
None
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.86A 4yp2B-4jkxA:
32.4		 4yp2B-4jkxA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5CF9_B_NCAB302_0
(RIBOSOME-INACTIVATIN
G PROTEIN MOMORDIN I)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 9 TYR A  76
GLY A 113
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
None
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.83A 5cf9B-4jkxA:
32.5		 5cf9B-4jkxA:
33.85
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5Z3J_A_NCAA302_0
(ABRIN A-CHAIN)		 4jkx BETA-GALACTOSIDE-SPE
CIFIC LECTIN 1 A
CHAIN
(Viscum
album) 		5 / 6 TYR A  76
VAL A  77
ILE A 160
GLU A 165
ARG A 168
 H35  A 305 (-4.2A)
None
H35  A 305 ( 4.5A)
H35  A 305 (-3.5A)
H35  A 305 (-3.3A)
 0.54A 5z3jA-4jkxA:
35.4		 5z3jA-4jkxA:
40.36