SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'H1N'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XBB_A_STIA1_1 (TYROSINE-PROTEINKINASE SYK) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 9 | VAL A 142ALA A 155GLY A 236PRO A 237LEU A 282 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.6A)H1N A 501 ( 4.5A)H1N A 501 (-4.8A) | 0.39A | 1xbbA-6ccfA:19.6 | 1xbbA-6ccfA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1XKK_A_FMMA91_2 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 9 | VAL A 142LYS A 157LEU A 214LEU A 228LEU A 232 | H1N A 501 (-4.4A)H1N A 501 (-2.8A)NoneNoneH1N A 501 (-4.3A) | 0.63A | 1xkkA-6ccfA:22.8 | 1xkkA-6ccfA:14.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2EUF_B_LQQB401_1 (CELL DIVISIONPROTEIN KINASE 6) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 8 / 12 | VAL A 142LYS A 157VAL A 212PHE A 230ASN A 280LEU A 282ALA A 292ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-2.8A)H1N A 501 (-4.9A)H1N A 501 (-3.7A)H1N A 501 (-4.5A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.65A | 2eufB-6ccfA:26.3 | 2eufB-6ccfA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2ITY_A_IREA2020_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 8 / 12 | GLY A 135VAL A 142ALA A 155LYS A 157LEU A 228GLY A 236LEU A 282ASP A 293 | H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)NoneH1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 (-3.5A) | 0.72A | 2ityA-6ccfA:23.2 | 2ityA-6ccfA:15.88 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2WGJ_A_VGHA2346_1 (HEPATOCYTE GROWTHFACTOR RECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 12 | GLY A 135VAL A 142ALA A 155GLY A 236ALA A 292ASP A 293 | H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.6A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.47A | 2wgjA-6ccfA:23.3 | 2wgjA-6ccfA:13.45 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_A_B49A1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | ILE A 134VAL A 142ALA A 155PHE A 230LEU A 232GLY A 236LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.7A)H1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.42A | 2y7jA-6ccfA:31.3 | 2y7jA-6ccfA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_B_B49B1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 10 | ILE A 134VAL A 142ALA A 155PHE A 230LEU A 232ASP A 293 | H1N A 501 (-4.3A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.7A)H1N A 501 (-4.3A)H1N A 501 (-3.5A) | 0.60A | 2y7jB-6ccfA:31.2 | 2y7jB-6ccfA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_B_B49B1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 10 | ILE A 134VAL A 142ALA A 155PHE A 230LEU A 232GLY A 236LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.7A)H1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.43A | 2y7jB-6ccfA:31.2 | 2y7jB-6ccfA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_C_B49C1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 10 | ILE A 134VAL A 142ALA A 155PHE A 230LEU A 232GLY A 236LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.7A)H1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.45A | 2y7jC-6ccfA:27.6 | 2y7jC-6ccfA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2Y7J_D_B49D1294_1 (PHOSPHORYLASE BKINASE GAMMACATALYTIC CHAIN,TESTIS/LIVER ISOFORM) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 10 | ILE A 134VAL A 142ALA A 155PHE A 230LEU A 232GLY A 236LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.7A)H1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.43A | 2y7jD-6ccfA:31.0 | 2y7jD-6ccfA:14.29 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3AOX_A_EMHA901_1 (ALK TYROSINE KINASERECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 10 | ALA A 155LYS A 157VAL A 212LEU A 232GLY A 236LEU A 282 | H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-4.9A)H1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.55A | 3aoxA-6ccfA:22.0 | 3aoxA-6ccfA:13.95 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3BBT_B_FMMB91_1 (RECEPTORTYROSINE-PROTEINKINASE ERBB-4) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 12 | VAL A 142ALA A 155LEU A 214LEU A 232GLY A 236LEU A 282 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)NoneH1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.42A | 3bbtB-6ccfA:23.2 | 3bbtB-6ccfA:13.98 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3CS9_A_NILA600_2 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 12 | ALA A 155GLY A 236HIS A 273LEU A 282ALA A 292 | H1N A 501 (-3.4A)H1N A 501 (-3.6A)NoneH1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.37A | 3cs9A-6ccfA:22.2 | 3cs9A-6ccfA:14.13 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3FUP_B_MI1B1_1 (TYROSINE-PROTEINKINASE JAK2) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 8 / 12 | GLY A 135GLY A 137VAL A 142ALA A 155LYS A 157VAL A 212LEU A 233LEU A 282 | H1N A 501 ( 3.8A)NoneH1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-4.9A)H1N A 501 (-4.6A)H1N A 501 (-4.8A) | 0.55A | 3fupB-6ccfA:24.4 | 3fupB-6ccfA:15.25 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3GCS_A_BAXA401_2 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 4 / 6 | VAL A 211LEU A 232ILE A 271ILE A 291 | NoneH1N A 501 (-4.3A)NoneNone | 0.57A | 3gcsA-6ccfA:21.1 | 3gcsA-6ccfA:12.01 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK3_A_0LIA1_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 12 | ALA A 155VAL A 212HIS A 273LEU A 282ALA A 292 | H1N A 501 (-3.4A)H1N A 501 (-4.9A)NoneH1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.46A | 3ik3A-6ccfA:22.2 | 3ik3A-6ccfA:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3IK3_B_0LIB2_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ABL1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 12 | ALA A 155VAL A 212HIS A 273LEU A 282ALA A 292 | H1N A 501 (-3.4A)H1N A 501 (-4.9A)NoneH1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.50A | 3ik3B-6ccfA:21.9 | 3ik3B-6ccfA:13.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3LFA_A_1N1A361_1 (MITOGEN-ACTIVATEDPROTEIN KINASE 14) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 4 / 8 | ALA A 155LYS A 157LEU A 228LEU A 232 | H1N A 501 (-3.4A)H1N A 501 (-2.8A)NoneH1N A 501 (-4.3A) | 0.42A | 3lfaA-6ccfA:21.5 | 3lfaA-6ccfA:11.17 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIY_A_B49A1_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 11 | ILE A 134ALA A 155LYS A 157VAL A 212PHE A 230GLY A 236LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-4.9A)H1N A 501 (-3.7A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.58A | 3miyA-6ccfA:23.4 | 3miyA-6ccfA:13.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3MIY_B_B49B2_1 (TYROSINE-PROTEINKINASE ITK/TSK) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 9 | ILE A 134ALA A 155LYS A 157PHE A 230GLY A 236LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-3.7A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.57A | 3miyB-6ccfA:23.2 | 3miyB-6ccfA:13.74 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OEZ_A_STIA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 12 | VAL A 142ALA A 155VAL A 212GLY A 236LEU A 282ALA A 292 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.50A | 3oezA-6ccfA:7.2 | 3oezA-6ccfA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3RGF_A_BAXA465_1 (CYCLIN-DEPENDENTKINASE 8) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 12 | VAL A 142ALA A 155PHE A 230LEU A 266HIS A 273ALA A 292 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.7A)NoneNoneH1N A 501 ( 3.9A) | 0.56A | 3rgfA-6ccfA:7.7 | 3rgfA-6ccfA:14.50 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3TI1_A_B49A299_1 (CYCLIN-DEPENDENTKINASE 2) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 9 | ILE A 134ALA A 155VAL A 212PHE A 230LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-3.7A)H1N A 501 (-4.8A) | 0.59A | 3ti1A-6ccfA:24.2 | 3ti1A-6ccfA:13.00 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3UG2_A_IREA1_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | VAL A 142ALA A 155LYS A 157LEU A 228LEU A 232GLY A 236LEU A 282 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)NoneH1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.57A | 3ug2A-6ccfA:23.4 | 3ug2A-6ccfA:15.85 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZD_A_LEVA1201_2 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 4 / 5 | LYS A 157VAL A 212LEU A 282ASP A 293 | H1N A 501 (-2.8A)H1N A 501 (-4.9A)H1N A 501 (-4.8A)H1N A 501 (-3.5A) | 1.10A | 3wzdA-6ccfA:6.3 | 3wzdA-6ccfA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3WZE_A_BAXA1201_2 (VASCULAR ENDOTHELIALGROWTH FACTORRECEPTOR 2) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 8 | VAL A 211VAL A 212LEU A 282ILE A 291ASP A 293 | NoneH1N A 501 (-4.9A)H1N A 501 (-4.8A)NoneH1N A 501 (-3.5A) | 0.71A | 3wzeA-6ccfA:22.3 | 3wzeA-6ccfA:17.08 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3ZBF_A_VGHA3000_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE ROS) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 12 | ALA A 155LEU A 232GLY A 236LEU A 282ASP A 293 | H1N A 501 (-3.4A)H1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 (-3.5A) | 0.43A | 3zbfA-6ccfA:12.9 | 3zbfA-6ccfA:12.30 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ANQ_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 9 | VAL A 142ALA A 155GLY A 236LEU A 282ALA A 292ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.55A | 4anqA-6ccfA:22.3 | 4anqA-6ccfA:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ANS_A_VGHA9000_1 (ALK TYROSINE KINASERECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 9 | VAL A 142ALA A 155GLY A 236LEU A 282ALA A 292ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.56A | 4ansA-6ccfA:22.3 | 4ansA-6ccfA:13.16 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4I41_A_MIXA500_1 (SERINE/THREONINE-PROTEIN KINASE PIM-1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | VAL A 142ALA A 155ASP A 275LYS A 277ASN A 280LEU A 282ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)NoneNoneH1N A 501 (-4.5A)H1N A 501 (-4.8A)H1N A 501 (-3.5A) | 0.63A | 4i41A-6ccfA:28.8 | 4i41A-6ccfA:13.41 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4KS8_A_B49A701_1 (SERINE/THREONINE-PROTEIN KINASE PAK 6) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 10 | ILE A 134ALA A 155VAL A 212LEU A 233GLY A 236LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-4.6A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.34A | 4ks8A-6ccfA:28.4 | 4ks8A-6ccfA:15.91 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXY_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | VAL A 142ALA A 155VAL A 212GLY A 236LEU A 282ALA A 292ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.58A | 4mxyB-6ccfA:23.8 | 4mxyB-6ccfA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4MXZ_B_DB8B601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | VAL A 142ALA A 155VAL A 212GLY A 236LEU A 282ALA A 292ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.58A | 4mxzB-6ccfA:23.8 | 4mxzB-6ccfA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4OTW_A_DB8A1101_1 (RECEPTORTYROSINE-PROTEINKINASE ERBB-3) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | VAL A 142LYS A 157VAL A 212GLY A 236LEU A 282ALA A 292ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-2.8A)H1N A 501 (-4.9A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.77A | 4otwA-6ccfA:23.1 | 4otwA-6ccfA:18.22 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMS_A_1N1A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 11 | ILE A 134ALA A 155LYS A 157LEU A 233LEU A 282ASP A 293 | H1N A 501 (-4.3A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-4.6A)H1N A 501 (-4.8A)H1N A 501 (-3.5A) | 0.68A | 4qmsA-6ccfA:28.9 | 4qmsA-6ccfA:14.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4QMZ_A_B49A401_1 (SERINE/THREONINE-PROTEIN KINASE 24) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 12 | ILE A 134GLY A 135VAL A 142ALA A 155LEU A 233LEU A 282 | H1N A 501 (-4.3A)H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.6A)H1N A 501 (-4.8A) | 0.35A | 4qmzA-6ccfA:28.6 | 4qmzA-6ccfA:14.05 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4RZ7_A_1E8A901_1 (CGMP-DEPENDENTPROTEIN KINASE,PUTATIVE) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 10 | ILE A 134ALA A 155LYS A 157LEU A 232LEU A 282 | H1N A 501 (-4.3A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-4.3A)H1N A 501 (-4.8A) | 0.60A | 4rz7A-6ccfA:12.0 | 4rz7A-6ccfA:7.23 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4TWP_A_AXIA601_1 (TYROSINE-PROTEINKINASE ABL1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 8 / 12 | VAL A 142ALA A 155LYS A 157GLY A 236ASN A 280LEU A 282ALA A 292ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-3.6A)H1N A 501 (-4.5A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.52A | 4twpA-6ccfA:24.7 | 4twpA-6ccfA:13.82 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4U5J_A_RXTA601_1 (PROTO-ONCOGENETYROSINE-PROTEINKINASE SRC) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 8 / 11 | GLY A 137VAL A 142ALA A 155GLY A 236ASN A 280LEU A 282ALA A 292ASP A 293 | NoneH1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.6A)H1N A 501 (-4.5A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A)H1N A 501 (-3.5A) | 0.51A | 4u5jA-6ccfA:24.8 | 4u5jA-6ccfA:14.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTHFACTOR RECEPTOR 4) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 12 | ALA A 155LEU A 266HIS A 273LEU A 282ALA A 292 | H1N A 501 (-3.4A)NoneNoneH1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.37A | 4uxqA-6ccfA:22.1 | 4uxqA-6ccfA:16.90 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4WKQ_A_IREA1101_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 12 | ALA A 155LYS A 157LEU A 228LEU A 232GLY A 236LEU A 282 | H1N A 501 (-3.4A)H1N A 501 (-2.8A)NoneH1N A 501 (-4.3A)H1N A 501 (-3.6A)H1N A 501 (-4.8A) | 0.34A | 4wkqA-6ccfA:24.0 | 4wkqA-6ccfA:16.07 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4XEY_B_1N1B601_1 (TYROSINE-PROTEINKINASE ABL1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | VAL A 142ALA A 155LYS A 157VAL A 212GLY A 236LEU A 282ALA A 292 | H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)H1N A 501 (-4.9A)H1N A 501 (-3.6A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.64A | 4xeyB-6ccfA:24.1 | 4xeyB-6ccfA:10.34 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5IZJ_G_AZ1G2_1 (CAMP-DEPENDENTPROTEIN KINASECATALYTIC SUBUNITALPHA47P-AZ1-DAR-DAR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 7 | GLY A 135GLY A 137VAL A 142LYS A 157LEU A 159 | H1N A 501 ( 3.8A)NoneH1N A 501 (-4.4A)H1N A 501 (-2.8A)None | 0.44A | 5izjA-6ccfA:28.2 | 5izjA-6ccfA:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5J5X_B_AZ1B2_1 (CAMP-DEPENDENTPROTEIN KINASECATALYTIC SUBUNITALPHA47P-AZ1-DAL-DAR-DAR-DAR-DAR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 7 | GLY A 135GLY A 137VAL A 142LYS A 157ASP A 293 | H1N A 501 ( 3.8A)NoneH1N A 501 (-4.4A)H1N A 501 (-2.8A)H1N A 501 (-3.5A) | 0.78A | 5j5xA-6ccfA:28.4 | 5j5xA-6ccfA:13.76 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2I_A_LQQA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | GLY A 135TYR A 139VAL A 142ALA A 155VAL A 212LEU A 282ALA A 292 | H1N A 501 ( 3.8A)NoneH1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.70A | 5l2iA-6ccfA:8.3 | 5l2iA-6ccfA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2I_A_LQQA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | GLY A 135VAL A 142ALA A 155VAL A 212PHE A 230LEU A 282ALA A 292 | H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-3.7A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.63A | 5l2iA-6ccfA:8.3 | 5l2iA-6ccfA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | GLY A 135VAL A 142ALA A 155VAL A 212PHE A 230LEU A 282ALA A 292 | H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-3.7A)H1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.75A | 5l2tA-6ccfA:8.3 | 5l2tA-6ccfA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5L2T_A_6ZZA900_1 (CYCLIN-DEPENDENTKINASE 6) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 7 / 12 | ILE A 134GLY A 135VAL A 142ALA A 155VAL A 212PHE A 230LEU A 282 | H1N A 501 (-4.3A)H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-4.9A)H1N A 501 (-3.7A)H1N A 501 (-4.8A) | 1.05A | 5l2tA-6ccfA:8.3 | 5l2tA-6ccfA:15.65 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5MO4_A_NILA601_2 (TYROSINE-PROTEINKINASE ABL1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 12 | ALA A 155VAL A 212HIS A 273LEU A 282ALA A 292 | H1N A 501 (-3.4A)H1N A 501 (-4.9A)NoneH1N A 501 (-4.8A)H1N A 501 ( 3.9A) | 0.47A | 5mo4A-6ccfA:16.1 | 5mo4A-6ccfA:11.56 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5VCY_A_DB8A401_2 (MEMBRANE-ASSOCIATEDTYROSINE- ANDTHREONINE-SPECIFICCDC2-INHIBITORYKINASE) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 4 / 4 | VAL A 212LEU A 232ASN A 280ASP A 293 | H1N A 501 (-4.9A)H1N A 501 (-4.3A)H1N A 501 (-4.5A)H1N A 501 (-3.5A) | 0.92A | 5vcyA-6ccfA:24.4 | 5vcyA-6ccfA:15.19 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5XV7_A_EMHA705_1 (SERINE-ARGININE (SR)PROTEIN KINASE 1) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 5 / 12 | GLY A 135VAL A 142ALA A 155PHE A 230ALA A 292 | H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-3.7A)H1N A 501 ( 3.9A) | 0.30A | 5xv7A-6ccfA:25.1 | 5xv7A-6ccfA:22.11 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5Y9M_X_NIOX401_1 (CASEIN KINASE IISUBUNIT ALPHA') |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 4 / 8 | VAL A 142LYS A 157PHE A 230ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-2.8A)H1N A 501 (-3.7A)H1N A 501 (-3.5A) | 0.51A | 5y9mX-6ccfA:24.3 | 5y9mX-6ccfA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YF9_B_NIOB401_1 (CASEIN KINASE IISUBUNIT ALPHA') |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 4 / 7 | VAL A 142LYS A 157PHE A 230ASP A 293 | H1N A 501 (-4.4A)H1N A 501 (-2.8A)H1N A 501 (-3.7A)H1N A 501 (-3.5A) | 0.70A | 5yf9B-6ccfA:24.2 | 5yf9B-6ccfA:23.53 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5YU9_A_1E8A1101_1 (EPIDERMAL GROWTHFACTOR RECEPTOR) |
6ccf | CALCIUM/CALMODULIN-DEPENDENT PROTEINKINASE KINASE 1 (Homosapiens) | 6 / 12 | GLY A 135VAL A 142ALA A 155LYS A 157LEU A 228LEU A 282 | H1N A 501 ( 3.8A)H1N A 501 (-4.4A)H1N A 501 (-3.4A)H1N A 501 (-2.8A)NoneH1N A 501 (-4.8A) | 0.66A | 5yu9A-6ccfA:22.3 | 5yu9A-6ccfA:23.96 |