SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GYC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_A_FFOA1002_1
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		4 / 5 TYR A 114
TYR A 116
PHE A  68
PRO A  33
 None
GYC  A  63 ( 4.8A)
None
None
 1.48A 1dfoB-3zulA:
undetectable		 1dfoB-3zulA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_B_FFOB2002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		4 / 5 TYR A 114
TYR A 116
PHE A  68
PRO A  33
 None
GYC  A  63 ( 4.8A)
None
None
 1.48A 1dfoA-3zulA:
undetectable		 1dfoA-3zulA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_C_FFOC3002_2
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		4 / 5 TYR A 114
TYR A 116
PHE A  68
PRO A  33
 None
GYC  A  63 ( 4.8A)
None
None
 1.48A 1dfoD-3zulA:
undetectable		 1dfoD-3zulA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1DFO_D_FFOD4002_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		4 / 5 TYR A 114
TYR A 116
PHE A  68
PRO A  33
 None
GYC  A  63 ( 4.8A)
None
None
 1.48A 1dfoC-3zulA:
undetectable		 1dfoC-3zulA:
19.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1MAA_B_DMEB996_1
(ACETYLCHOLINESTERASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		4 / 6 TYR A  87
GLU A 144
ILE A 118
TYR A 116
 None
None
None
GYC  A  63 ( 4.8A)
 1.13A 1maaB-3zulA:
undetectable
1maaD-3zulA:
undetectable		 1maaB-3zulA:
17.50
1maaD-3zulA:
17.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JFA_B_RALB600_1
(ESTROGEN RECEPTOR)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		5 / 12 GLU A 211
ARG A  66
MET A  14
GLY A  27
LEU A  42
 GYC  A  63 ( 3.5A)
GYC  A  63 ( 2.9A)
None
None
None
 1.11A 2jfaB-3zulA:
undetectable		 2jfaB-3zulA:
22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VMY_A_FFOA505_0
(SERINE
HYDROXYMETHYLTRANSFE
RASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		4 / 6 TYR A 114
TYR A 116
PHE A  68
PRO A  33
 None
GYC  A  63 ( 4.8A)
None
None
 1.46A 2vmyA-3zulA:
undetectable		 2vmyA-3zulA:
23.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3BA0_A_HAEA477_1
(MACROPHAGE
METALLOELASTASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		3 / 3 HIS A 212
GLU A 211
HIS A 193
 None
GYC  A  63 ( 3.5A)
GYC  A  63 ( 3.3A)
 0.89A 3ba0A-3zulA:
undetectable		 3ba0A-3zulA:
18.61
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3CCF_B_BEZB261_0
(CYCLOPROPANE-FATTY-A
CYL-PHOSPHOLIPID
SYNTHASE)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		4 / 8 ASN A 105
ILE A 107
PHE A  68
TYR A 116
 GYC  A  63 ( 4.3A)
None
None
GYC  A  63 ( 4.8A)
 1.13A 3ccfB-3zulA:
undetectable		 3ccfB-3zulA:
21.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L9Q_A_9TPA601_1
(SERUM ALBUMIN)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		5 / 12 LEU A  42
ALA A 103
TYR A 116
ILE A  10
GLY A  31
 None
None
GYC  A  63 ( 4.8A)
None
None
 1.35A 4l9qA-3zulA:
undetectable		 4l9qA-3zulA:
16.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IKT_B_TLFB601_1
(PROSTAGLANDIN G/H
SYNTHASE 2)		 3zul FLUORESCENT PROTEIN
DRONPA
(Echinophyllia
sp.
SC22) 		3 / 3 TYR A 116
TYR A  78
SER A  82
 GYC  A  63 ( 4.8A)
None
None
 0.96A 5iktB-3zulA:
undetectable		 5iktB-3zulA:
16.76