SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GTB'


List of Similar Pattern of Amino Acids


Hit pattern: 3D amino acid arrangements similar to known drug binding site

Query pattern: Residues from known binding site for annotated drug that match the hit pattern


(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID
Hit
Macromolecule
Res.
Matches
Interface HETATM RMSD Dali
Z-score
Seq.
Identity (%)
View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
6 / 7 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.31A 11gsA-3o76A:
36.5
11gsA-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
6 / 7 TYR A   7
PHE A   8
GLY A  12
ARG A  13
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.30A 11gsB-3o76A:
36.4
11gsB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
4 / 7 TYR A 108
GLY A 205
TYR A   7
GLY A  12
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
None
None
0.70A 11gsB-3o76A:
36.4
11gsB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
13GS_A_SASA211_1
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
8 / 10 TYR A   7
PHE A   8
PRO A   9
VAL A  10
ARG A  13
TYR A 108
PRO A 202
GLY A 205
None
GTB  A 210 (-4.5A)
None
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
0.31A 13gsA-3o76A:
36.0
13gsA-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
13GS_B_SASB211_1
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 9 PHE A   8
PRO A   9
VAL A  10
ARG A  13
TYR A 108
PRO A 202
GLY A 205
GTB  A 210 (-4.5A)
None
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
0.33A 13gsB-3o76A:
36.1
13gsB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 LEU A  43
THR A  46
LEU A  48
GLY A  50
LEU A  52
None
None
None
None
GTB  A 210 (-4.9A)
1.17A 1gtiA-3o76A:
35.1
1gtiA-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 THR A  46
LEU A  48
GLY A  50
LEU A  52
TYR A  63
None
None
None
GTB  A 210 (-4.9A)
None
0.59A 1gtiA-3o76A:
35.1
1gtiA-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 TRP A  38
LEU A  43
LEU A  48
GLY A  50
LEU A  52
GTB  A 210 (-4.0A)
None
None
None
GTB  A 210 (-4.9A)
0.64A 1gtiA-3o76A:
35.1
1gtiA-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_A_CCSA47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 TRP A  38
LEU A  48
GLY A  50
LEU A  52
TYR A  63
GTB  A 210 (-4.0A)
None
None
GTB  A 210 (-4.9A)
None
0.41A 1gtiA-3o76A:
35.1
1gtiA-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 THR A  46
LEU A  48
GLY A  50
LEU A  52
TYR A  63
None
None
None
GTB  A 210 (-4.9A)
None
0.43A 1gtiB-3o76A:
35.0
1gtiB-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 TRP A  38
LEU A  43
LEU A  48
GLY A  50
TYR A  63
GTB  A 210 (-4.0A)
None
None
None
None
0.84A 1gtiB-3o76A:
35.0
1gtiB-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_B_CCSB47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 TRP A  38
LEU A  48
GLY A  50
LEU A  52
TYR A  63
GTB  A 210 (-4.0A)
None
None
GTB  A 210 (-4.9A)
None
0.39A 1gtiB-3o76A:
35.0
1gtiB-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 6 TRP A  38
LEU A  48
GLY A  50
LYS A  54
TYR A  63
GTB  A 210 (-4.0A)
None
None
None
None
0.56A 1gtiC-3o76A:
34.8
1gtiC-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_C_CCSC47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 6 TRP A  38
THR A  46
GLY A  50
LYS A  54
TYR A  63
GTB  A 210 (-4.0A)
None
None
None
None
1.08A 1gtiC-3o76A:
34.8
1gtiC-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_D_CCSD47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 7 TRP A  38
THR A  46
LEU A  48
GLY A  50
LEU A  52
LYS A  54
TYR A  63
GTB  A 210 (-4.0A)
None
None
None
GTB  A 210 (-4.9A)
None
None
0.42A 1gtiD-3o76A:
34.9
1gtiD-3o76A:
99.52
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
1GTI_E_CCSE47_0
(GLUTATHIONE
S-TRANSFERASE)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 7 TRP A  38
THR A  46
LEU A  48
GLY A  50
LEU A  52
LYS A  54
TYR A  63
GTB  A 210 (-4.0A)
None
None
None
GTB  A 210 (-4.9A)
None
None
0.62A 1gtiE-3o76A:
34.7
1gtiE-3o76A:
99.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1J7K_A_ACTA701_0
(HOLLIDAY JUNCTION
DNA HELICASE RUVB)
2ycd GLUTATHIONE
S-TRANSFERASE

(Agrobacterium
tumefaciens)
4 / 4 GLY A  31
LEU A  32
GLY A  29
ARG A  30
None
GTB  A 501 (-4.0A)
None
GTB  A 501 ( 4.9A)
1.12A 1j7kA-2ycdA:
undetectable
1j7kA-2ycdA:
22.97
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 8 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TRP A  38
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.0A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.40A 2gssA-3o76A:
36.5
2gssA-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 8 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TRP A  38
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.0A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.40A 2gssB-3o76A:
36.5
2gssB-3o76A:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VUF_B_FUAB2002_1
(SERUM ALBUMIN)
5agy GLUTATHIONE
S-TRANSFERASE

(Glycine
max)
4 / 9 ILE A 155
ARG A  18
ALA A  70
VAL A  71
None
GTB  A1222 ( 4.9A)
None
None
1.03A 2vufB-5agyA:
3.4
2vufB-5agyA:
16.75
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
8 / 9 TYR A   7
PHE A   8
PRO A   9
VAL A  10
GLY A  12
ARG A  13
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
None
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.31A 3csjB-3o76A:
36.4
3csjB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3DGQ_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
4 / 5 TYR A   7
ARG A  13
TYR A 108
THR A 109
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
None
0.17A 3dgqA-3o76A:
36.4
3dgqA-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 PHE A   8
VAL A  10
TYR A 108
THR A 105
GLY A 205
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
1.14A 3gssA-3o76A:
36.6
3gssA-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GSS_A_EAAA212_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
6 / 7 TYR A   7
PHE A   8
VAL A  10
TYR A 108
THR A 109
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
0.19A 3gssA-3o76A:
36.6
3gssA-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 7 PHE A   8
VAL A  10
TYR A 108
THR A 105
GLY A 205
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
1.06A 3gssB-3o76A:
36.6
3gssB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3GSS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P1-1)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
6 / 7 TYR A   7
PHE A   8
VAL A  10
TYR A 108
THR A 109
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.1A)
None
GTB  A 210 (-3.7A)
0.35A 3gssB-3o76A:
36.6
3gssB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HJO_A_EAAA211_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 8 TYR A   7
PHE A   8
VAL A  10
TRP A  38
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.0A)
GTB  A 210 (-3.7A)
0.19A 3hjoA-3o76A:
36.6
3hjoA-3o76A:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3HJO_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 8 PHE A   8
VAL A  10
TRP A  38
ASN A 204
GLY A 205
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.0A)
None
GTB  A 210 (-3.7A)
0.30A 3hjoB-3o76A:
36.6
3hjoB-3o76A:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KM6_A_EAAA222_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 10 TYR A   7
PHE A   8
VAL A  10
GLY A  12
TRP A  38
ASN A 204
GLY A 205
None
GTB  A 210 (-4.5A)
None
None
GTB  A 210 (-4.0A)
None
GTB  A 210 (-3.7A)
0.25A 3km6A-3o76A:
36.4
3km6A-3o76A:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
5 / 9 PHE A   8
VAL A  10
VAL A 104
ASN A 204
GLY A 205
GTB  A 210 (-4.5A)
None
None
None
GTB  A 210 (-3.7A)
1.29A 3km6B-3o76A:
36.6
3km6B-3o76A:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KM6_B_EAAB222_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
6 / 9 TYR A   7
PHE A   8
VAL A  10
TRP A  38
ASN A 204
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.0A)
None
GTB  A 210 (-3.7A)
0.27A 3km6B-3o76A:
36.6
3km6B-3o76A:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KMO_A_EAAA214_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 9 TYR A   7
PHE A   8
VAL A  10
GLY A  12
TRP A  38
ASN A 204
GLY A 205
None
GTB  A 210 (-4.5A)
None
None
GTB  A 210 (-4.0A)
None
GTB  A 210 (-3.7A)
0.32A 3kmoA-3o76A:
36.0
3kmoA-3o76A:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3KMO_B_EAAB213_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
6 / 7 TYR A   7
PHE A   8
VAL A  10
TRP A  38
ASN A 204
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-4.0A)
None
GTB  A 210 (-3.7A)
0.35A 3kmoB-3o76A:
36.2
3kmoB-3o76A:
84.21
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 8 TYR A   7
PHE A   8
VAL A  10
ARG A  13
TRP A  38
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.0A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.46A 3n9jA-3o76A:
36.5
3n9jA-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
7 / 8 TYR A   7
PHE A   8
VAL A  10
GLY A  12
ARG A  13
TYR A 108
GLY A 205
None
GTB  A 210 (-4.5A)
None
None
GTB  A 210 (-3.9A)
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
0.35A 3n9jB-3o76A:
36.1
3n9jB-3o76A:
84.69
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)
3o76 GLUTATHIONE
S-TRANSFERASE P 1

(Mus
musculus)
4 / 8 TYR A 108
GLY A 205
TYR A   7
GLY A  12
GTB  A 210 (-4.1A)
GTB  A 210 (-3.7A)
None
None
0.73A 3n9jB-3o76A:
36.1
3n9jB-3o76A:
84.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)
5agy GLUTATHIONE
S-TRANSFERASE

(Glycine
max)
5 / 6 PHE A  15
ARG A  18
PRO A  55
GLU A  66
SER A  67
GTB  A1222 (-3.8A)
GTB  A1222 ( 4.9A)
GTB  A1222 (-4.4A)
PO4  A1223 ( 2.9A)
GTB  A1222 (-2.7A)
0.38A 3vlnA-5agyA:
24.1
3vlnA-5agyA:
29.27