SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GTA'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2)	6d0y	NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 (Homo sapiens)	4 / 6	SER A 63 ILE A 66 TYR A 88 ASP A 114	None None None GTA A 201 (-2.8A)	1.12A	3q70A-6d0yA: undetectable	3q70A-6d0yA: 13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3Q70_A_RITA2001_2 (CANDIDAPEPSIN-2)	6d0y	NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 (Homo sapiens)	4 / 6	SER A 63 ILE A 66 TYR A 88 ASP A 116	None None None GTA A 201 (-2.9A)	1.08A	3q70A-6d0yA: undetectable	3q70A-6d0yA: 13.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5IGJ_A_CTYA402_2 (MACROLIDE 2'-PHOSPHOTRANSFERAS E)	6d0y	NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2 (Homo sapiens)	4 / 5	HIS A 24 LEU A 36 TYR A 43 PHE A 83	None None GTA A 201 (-3.4A) GTA A 201 (-3.7A)	1.40A	5igjA-6d0yA: undetectable	5igjA-6d0yA: 16.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TZO_B_7V7B202_1 (ENDO-1,4-BETA-XYLANA SE A)	3hxg	EUKARYOTIC TRANSLATION INITIATION FACTOR 4E (Schistosoma mansoni)	4 / 8	TRP A 43 ARG A 99 GLN A 187 TRP A 89	GTA A 1 (-3.4A) None None GTA A 1 (-3.6A)	1.41A	5tzoB-3hxgA: undetectable	5tzoB-3hxgA: 21.26

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["3Q70_A_RITA2001_2","CANDIDAPEPSIN-2","6d0y","NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2","Homo sapiens",4,"SER A  63;ILE A  66;TYR A  88;ASP A 114","None;None;None;GTA A 201 (-2.8A)","1.12A","3q70A-6d0yA:undetectable",null],["3Q70_A_RITA2001_2","CANDIDAPEPSIN-2","6d0y","NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2","Homo sapiens",4,"SER A  63;ILE A  66;TYR A  88;ASP A 116","None;None;None;GTA A 201 (-2.9A)","1.08A","3q70A-6d0yA:undetectable","3q70A-6d0yA:13.74"],["5IGJ_A_CTYA402_2","MACROLIDE 2'-PHOSPHOTRANSFERASE","6d0y","NUCLEAR CAP-BINDING PROTEIN SUBUNIT 2","Homo sapiens",4,"HIS A  24;LEU A  36;TYR A  43;PHE A  83","None;None;GTA A 201 (-3.4A);GTA A 201 (-3.7A)","1.40A","5igjA-6d0yA:undetectable","3q70A-6d0yA:13.74"],["5TZO_B_7V7B202_1","ENDO-1,4-BETA-XYLANASE A","3hxg","EUKARYOTIC TRANSLATION INITIATION FACTOR 4E","Schistosoma mansoni",4,"TRP A  43;ARG A  99;GLN A 187;TRP A  89","GTA A   1 (-3.4A);None;None;GTA A   1 (-3.6A)","1.41A","5tzoB-3hxgA:undetectable","5igjA-6d0yA:16.41"]]