SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GSP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1c9sA-2q1yA:
undetectable
1c9sK-2q1yA:
undetectable		 1c9sA-2q1yA:
12.94
1c9sK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1c9sA-2q1yA:
undetectable
1c9sB-2q1yA:
undetectable		 1c9sA-2q1yA:
12.94
1c9sB-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1c9sB-2q1yA:
undetectable
1c9sC-2q1yA:
undetectable		 1c9sB-2q1yA:
12.94
1c9sC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1c9sC-2q1yA:
undetectable
1c9sD-2q1yA:
undetectable		 1c9sC-2q1yA:
12.94
1c9sD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_E_TRPE81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1c9sD-2q1yA:
undetectable
1c9sE-2q1yA:
undetectable		 1c9sD-2q1yA:
12.94
1c9sE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1c9sE-2q1yA:
undetectable
1c9sF-2q1yA:
undetectable		 1c9sE-2q1yA:
12.94
1c9sF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1c9sF-2q1yA:
undetectable
1c9sG-2q1yA:
undetectable		 1c9sF-2q1yA:
12.94
1c9sG-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1c9sG-2q1yA:
undetectable
1c9sH-2q1yA:
undetectable		 1c9sG-2q1yA:
12.94
1c9sH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1c9sH-2q1yA:
undetectable
1c9sI-2q1yA:
undetectable		 1c9sH-2q1yA:
12.94
1c9sI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 107
ALA A  79
THR A  42
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
None
 0.78A 1c9sI-2q1yA:
undetectable
1c9sJ-2q1yA:
undetectable		 1c9sI-2q1yA:
12.94
1c9sJ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_K_TRPK81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1c9sJ-2q1yA:
undetectable
1c9sK-2q1yA:
undetectable		 1c9sJ-2q1yA:
12.94
1c9sK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_L_TRPL81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1c9sL-2q1yA:
undetectable
1c9sM-2q1yA:
undetectable		 1c9sL-2q1yA:
12.94
1c9sM-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_M_TRPM81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1c9sM-2q1yA:
undetectable
1c9sN-2q1yA:
undetectable		 1c9sM-2q1yA:
12.94
1c9sN-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1c9sO-2q1yA:
undetectable
1c9sP-2q1yA:
undetectable		 1c9sO-2q1yA:
12.94
1c9sP-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1c9sS-2q1yA:
undetectable
1c9sT-2q1yA:
undetectable		 1c9sS-2q1yA:
12.94
1c9sT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1C9S_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 107
ALA A  79
THR A  42
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
None
 0.79A 1c9sU-2q1yA:
undetectable
1c9sV-2q1yA:
undetectable		 1c9sU-2q1yA:
12.94
1c9sV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1CD2_A_FOLA307_1
(DIHYDROFOLATE
REDUCTASE)		 4tmz EIF5B
(Chaetomium
thermophilum) 		3 / 3 GLU B 552
ILE B 556
ARG B 605
 MG  B 902 ( 3.9A)
GSP  B 901 (-4.2A)
None
 0.71A 1cd2A-4tmzB:
undetectable		 1cd2A-4tmzB:
18.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 8 SER A  49
SER A  52
GLY A 221
GLY A  45
 GSP  A1382 (-3.4A)
MG  A1381 ( 2.0A)
GSP  A1382 (-3.4A)
None
 0.66A 1f5lA-2xtzA:
undetectable		 1f5lA-2xtzA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1gtfA-2q1yA:
undetectable
1gtfK-2q1yA:
undetectable		 1gtfA-2q1yA:
12.94
1gtfK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1gtfA-2q1yA:
undetectable
1gtfB-2q1yA:
undetectable		 1gtfA-2q1yA:
12.94
1gtfB-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_C_TRPC81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1gtfB-2q1yA:
undetectable
1gtfC-2q1yA:
undetectable		 1gtfB-2q1yA:
12.94
1gtfC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_D_TRPD81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1gtfC-2q1yA:
undetectable
1gtfD-2q1yA:
undetectable		 1gtfC-2q1yA:
12.94
1gtfD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1gtfE-2q1yA:
undetectable
1gtfF-2q1yA:
undetectable		 1gtfE-2q1yA:
12.94
1gtfF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_G_TRPG81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1gtfF-2q1yA:
undetectable
1gtfG-2q1yA:
undetectable		 1gtfF-2q1yA:
12.94
1gtfG-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1gtfG-2q1yA:
undetectable
1gtfH-2q1yA:
undetectable		 1gtfG-2q1yA:
12.94
1gtfH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_I_TRPI81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1gtfH-2q1yA:
undetectable
1gtfI-2q1yA:
undetectable		 1gtfH-2q1yA:
12.94
1gtfI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_J_TRPJ81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1gtfI-2q1yA:
undetectable
1gtfJ-2q1yA:
undetectable		 1gtfI-2q1yA:
12.94
1gtfJ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_O_TRPO81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1gtfO-2q1yA:
undetectable
1gtfP-2q1yA:
undetectable		 1gtfO-2q1yA:
12.94
1gtfP-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1gtfP-2q1yA:
undetectable
1gtfQ-2q1yA:
undetectable		 1gtfP-2q1yA:
12.94
1gtfQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_T_TRPT81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1gtfT-2q1yA:
undetectable
1gtfU-2q1yA:
undetectable		 1gtfT-2q1yA:
12.94
1gtfU-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_U_TRPU81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1gtfU-2q1yA:
undetectable
1gtfV-2q1yA:
undetectable		 1gtfU-2q1yA:
12.94
1gtfV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTF_V_TRPV81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN
(TRAP))		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1gtfL-2q1yA:
undetectable
1gtfV-2q1yA:
undetectable		 1gtfL-2q1yA:
12.94
1gtfV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_A_TRPA81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		4 / 7 GLY A 107
ALA A  79
THR A  42
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
None
 0.79A 1gtnA-2q1yA:
undetectable
1gtnK-2q1yA:
undetectable		 1gtnA-2q1yA:
12.94
1gtnK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_B_TRPB81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 1gtnA-2q1yA:
undetectable
1gtnB-2q1yA:
undetectable		 1gtnA-2q1yA:
12.94
1gtnB-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_F_TRPF81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 107
ALA A  79
THR A  42
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
None
 0.79A 1gtnE-2q1yA:
undetectable
1gtnF-2q1yA:
undetectable		 1gtnE-2q1yA:
12.94
1gtnF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_H_TRPH81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1gtnG-2q1yA:
undetectable
1gtnH-2q1yA:
undetectable		 1gtnG-2q1yA:
12.94
1gtnH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_N_TRPN81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1gtnN-2q1yA:
undetectable
1gtnO-2q1yA:
undetectable		 1gtnN-2q1yA:
12.94
1gtnO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_P_TRPP81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1gtnP-2q1yA:
undetectable
1gtnQ-2q1yA:
undetectable		 1gtnP-2q1yA:
12.94
1gtnQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_R_TRPR81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.37A 1gtnR-2q1yA:
undetectable
1gtnS-2q1yA:
undetectable		 1gtnR-2q1yA:
12.94
1gtnS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1GTN_S_TRPS81_0
(TRP RNA-BINDING
ATTENUATION PROTEIN)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1gtnS-2q1yA:
undetectable
1gtnT-2q1yA:
undetectable		 1gtnS-2q1yA:
12.94
1gtnT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1IG3_B_VIBB501_1
(THIAMIN
PYROPHOSPHOKINASE)		 1tnd TRANSDUCIN
(Bos
taurus) 		4 / 7 GLN A 168
ASP A 169
LEU A 155
SER A 147
 None
None
None
GSP  A 351 (-3.3A)
 0.94A 1ig3A-1tndA:
2.8
1ig3B-1tndA:
2.9		 1ig3A-1tndA:
20.24
1ig3B-1tndA:
20.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JG2_A_ADNA500_1
(PROTEIN-L-ISOASPARTA
TE
O-METHYLTRANSFERASE)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 12 GLY A 108
GLY A 102
LEU A 103
GLY A  71
VAL A  99
 GSP  A1342 (-4.0A)
GSP  A1342 ( 4.1A)
None
None
None
 1.16A 1jg2A-4b45A:
3.5		 1jg2A-4b45A:
19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TNL_A_TPAA900_1
(TRYPSIN)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 6 SER A  49
SER A  52
GLY A 221
GLY A  45
 GSP  A1382 (-3.4A)
MG  A1381 ( 2.0A)
GSP  A1382 (-3.4A)
None
 0.75A 1tnlA-2xtzA:
undetectable		 1tnlA-2xtzA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_A_TRPA81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1utdA-2q1yA:
undetectable
1utdB-2q1yA:
undetectable		 1utdA-2q1yA:
12.94
1utdB-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_B_TRPB81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1utdB-2q1yA:
undetectable
1utdC-2q1yA:
undetectable		 1utdB-2q1yA:
12.94
1utdC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_C_TRPC81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1utdC-2q1yA:
undetectable
1utdD-2q1yA:
undetectable		 1utdC-2q1yA:
12.94
1utdD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_D_TRPD81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1utdD-2q1yA:
undetectable
1utdE-2q1yA:
undetectable		 1utdD-2q1yA:
12.94
1utdE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_F_TRPF81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1utdF-2q1yA:
undetectable
1utdG-2q1yA:
undetectable		 1utdF-2q1yA:
12.94
1utdG-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_G_TRPG81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1utdG-2q1yA:
undetectable
1utdH-2q1yA:
undetectable		 1utdG-2q1yA:
12.94
1utdH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_I_TRPI81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		4 / 8 GLY A 107
ALA A  79
THR A  42
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
None
 0.81A 1utdI-2q1yA:
undetectable
1utdJ-2q1yA:
undetectable		 1utdI-2q1yA:
12.94
1utdJ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_J_TRPJ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 8 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 1utdJ-2q1yA:
undetectable
1utdK-2q1yA:
undetectable		 1utdJ-2q1yA:
12.94
1utdK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_K_TRPK81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.37A 1utdA-2q1yA:
undetectable
1utdK-2q1yA:
undetectable		 1utdA-2q1yA:
12.94
1utdK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_M_TRPM81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1utdM-2q1yA:
undetectable
1utdN-2q1yA:
undetectable		 1utdM-2q1yA:
12.94
1utdN-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_N_TRPN81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 1utdN-2q1yA:
undetectable
1utdO-2q1yA:
undetectable		 1utdN-2q1yA:
12.94
1utdO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_Q_TRPQ81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 1utdQ-2q1yA:
undetectable
1utdR-2q1yA:
undetectable		 1utdQ-2q1yA:
12.94
1utdR-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UTD_R_TRPR81_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 1utdR-2q1yA:
undetectable
1utdS-2q1yA:
undetectable		 1utdR-2q1yA:
12.94
1utdS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1XR2_B_C2FB1201_0
(5-METHYLTETRAHYDROPT
EROYLTRIGLUTAMATE--H
OMOCYSTEINE
METHYLTRANSFERASE)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 8 LYS A  59
LYS A 288
THR A 194
GLU A 247
 None
GSP  A1382 (-3.1A)
None
None
 1.48A 1xr2B-2xtzA:
1.7		 1xr2B-2xtzA:
18.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1Z2B_C_VLBC800_2
(TUBULIN ALPHA CHAIN)		 2hf8 PROBABLE HYDROGENASE
NICKEL INCORPORATION
PROTEIN HYPB
(Methanocaldococc
us
jannaschii) 		4 / 5 VAL A 165
ASN A 167
VAL A 209
ILE A 139
 None
GSP  A 300 (-3.2A)
None
None
 1.07A 1z2bC-2hf8A:
undetectable		 1z2bC-2hf8A:
22.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 4d0m RAS-RELATED PROTEIN
RAB-11A
(Homo
sapiens) 		5 / 12 THR B  43
GLY B  23
GLY B  21
GLY B  69
ASP B 127
 MG  B2001 ( 2.7A)
GSP  B2000 (-3.0A)
GSP  B2000 (-3.5A)
GSP  B2000 (-4.1A)
GSP  B2000 (-2.9A)
 0.99A 2b25A-4d0mB:
undetectable		 2b25A-4d0mB:
19.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5cyp SEPTIN-9
(Homo
sapiens) 		5 / 12 THR A  64
GLY A  35
GLY A  33
GLY A  90
ASP A 172
 MG  A 302 ( 2.9A)
GSP  A 301 (-3.1A)
GSP  A 301 (-3.3A)
GSP  A 301 ( 3.8A)
GSP  A 301 (-2.6A)
 0.95A 2b25A-5cypA:
2.1		 2b25A-5cypA:
20.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 THR A 146
GLY A 122
GLY A 120
GLY A 182
ASP A 265
 MG  A 401 ( 3.2A)
GSP  A 402 (-3.1A)
GSP  A 402 (-3.5A)
GSP  A 402 (-3.4A)
GSP  A 402 (-2.8A)
 0.93A 2b25A-5irrA:
undetectable		 2b25A-5irrA:
20.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_B_NCAB1246_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 7 GLY A 221
SER A  49
ARG A 226
GLU A 247
 GSP  A1382 (-3.4A)
GSP  A1382 (-3.4A)
None
None
 1.05A 2c8aB-2xtzA:
undetectable		 2c8aB-2xtzA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2C8A_D_NCAD1247_0
(MONO-ADP-RIBOSYLTRAN
SFERASE C3)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 7 GLY A 221
SER A  49
ARG A 226
GLU A 247
 GSP  A1382 (-3.4A)
GSP  A1382 (-3.4A)
None
None
 1.08A 2c8aD-2xtzA:
undetectable		 2c8aD-2xtzA:
21.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_A_9CRA501_1
(CYTOCHROME P450 2C8)		 1yr7 ATP(GTP)BINDING
PROTEIN
(Pyrococcus
abyssi) 		5 / 11 GLY A 104
ILE A 130
SER A  11
ALA A 163
ILE A 152
 GSP  A 401 (-3.5A)
None
GSP  A 401 (-3.6A)
None
None
 1.15A 2nnhA-1yr7A:
0.0		 2nnhA-1yr7A:
20.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTV_A_NCAA1301_0
(CATIONIC TRYPSIN)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 6 SER A  49
SER A  52
GLY A 221
GLY A  45
 GSP  A1382 (-3.4A)
MG  A1381 ( 2.0A)
GSP  A1382 (-3.4A)
None
 0.73A 2otvA-2xtzA:
undetectable		 2otvA-2xtzA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 GLY A 148
GLY A  14
GLY A  11
GLY A 144
ILE A  17
 None
None
GSP  A2466 (-3.1A)
GSP  A2466 (-3.0A)
None
 0.99A 2oxtA-1z5vA:
undetectable		 2oxtA-1z5vA:
18.91
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OXT_A_SAMA300_0
(NUCLEOSIDE-2'-O-METH
YLTRANSFERASE)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 12 GLY A 110
GLY A  12
GLY A   9
GLY A 106
VAL A 100
 None
None
GSP  A1342 (-3.5A)
GSP  A1342 (-3.9A)
None
 0.98A 2oxtA-4b45A:
2.9		 2oxtA-4b45A:
23.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2PKM_A_ADNA501_1
(ADENOSINE KINASE)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 12 ALA A 112
GLY A 110
GLY A 108
ALA A  11
GLY A  66
 None
None
GSP  A1342 (-4.0A)
GSP  A1342 (-3.3A)
GSP  A1342 (-3.4A)
 0.88A 2pkmA-4b45A:
6.2		 2pkmA-4b45A:
23.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2UXP_A_CLMA1211_0
(HTH-TYPE
TRANSCRIPTIONAL
REGULATOR TTGR)		 2hf8 PROBABLE HYDROGENASE
NICKEL INCORPORATION
PROTEIN HYPB
(Methanocaldococc
us
jannaschii) 		5 / 8 GLU A  51
LEU A 200
LEU A 198
VAL A 165
ILE A 142
 None
GSP  A 300 (-4.2A)
None
None
None
 1.45A 2uxpA-2hf8A:
undetectable		 2uxpA-2hf8A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 1tnd TRANSDUCIN
(Bos
taurus) 		4 / 8 SER A  40
SER A  43
GLY A 199
GLY A  36
 GSP  A 351 (-3.2A)
MG  A 352 ( 2.2A)
GSP  A 351 (-3.6A)
None
 0.79A 2vinA-1tndA:
undetectable		 2vinA-1tndA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 8 SER A  49
SER A  52
GLY A 221
GLY A  45
 GSP  A1382 (-3.4A)
MG  A1381 ( 2.0A)
GSP  A1382 (-3.4A)
None
 0.70A 2vinA-2xtzA:
undetectable		 2vinA-2xtzA:
22.31
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WD9_C_IBPC1570_1
(ACYL-COENZYME A
SYNTHETASE ACSM2A,
MITOCHONDRIAL)		 1tnd TRANSDUCIN
(Bos
taurus) 		5 / 10 THR A  44
ILE A 220
LEU A  35
GLY A 198
GLY A  38
 GSP  A 351 (-3.8A)
None
None
GSP  A 351 (-3.6A)
GSP  A 351 ( 3.8A)
 1.17A 2wd9C-1tndA:
undetectable		 2wd9C-1tndA:
19.69
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2YLO_A_TESA1920_1
(ANDROGEN RECEPTOR)		 4tmz EIF5B
(Chaetomium
thermophilum) 		5 / 12 LEU B 617
LEU B 633
GLN B 693
VAL B 686
THR B 534
 None
None
None
None
GSP  B 901 (-4.3A)
 1.43A 2yloA-4tmzB:
undetectable		 2yloA-4tmzB:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EL0_A_1UNA201_2
(PROTEASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 9 ASP A 265
VAL A 322
GLY A 122
ALA A 353
ILE A 323
 GSP  A 402 (-2.8A)
None
GSP  A 402 (-3.1A)
None
GSP  A 402 (-4.4A)
 1.01A 3el0B-5irrA:
undetectable		 3el0B-5irrA:
15.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ELU_A_SAMA4633_0
(METHYLTRANSFERASE)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 107
GLY A 104
GLY A  69
THR A 108
ILE A  16
 GSP  A 401 (-3.6A)
GSP  A 401 (-3.6A)
GSP  A 401 (-3.8A)
None
None
 1.06A 3eluA-2q1yA:
undetectable		 3eluA-2q1yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EMB_A_SAMA4633_0
(METHYLTRANSFERASE)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 107
GLY A 104
GLY A  69
THR A 108
ILE A  16
 GSP  A 401 (-3.6A)
GSP  A 401 (-3.6A)
GSP  A 401 (-3.8A)
None
None
 1.03A 3embA-2q1yA:
undetectable		 3embA-2q1yA:
22.37
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IHT_A_SAMA200_0
(S-ADENOSYL-L-METHION
INE METHYL
TRANSFERASE)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 GLY A 146
GLY A 144
ILE A 118
ASP A  68
LEU A  67
 GSP  A2466 (-4.0A)
GSP  A2466 (-3.0A)
None
MG  A 475 ( 4.0A)
None
 0.91A 3ihtA-1z5vA:
2.2		 3ihtA-1z5vA:
14.14
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_A_SAMA465_0
(RRNA METHYLASE)		 2xka FTSZ/TUBULIN-RELATED
PROTEIN
(Bacillus
thuringiensis) 		5 / 12 PRO A  89
GLY A 140
GLY A 139
ASP A  94
LEU A 152
 None
GSP  A 900 (-3.3A)
GSP  A 900 (-3.3A)
None
None
 1.02A 3m6vA-2xkaA:
2.7		 3m6vA-2xkaA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6V_B_SAMB465_0
(RRNA METHYLASE)		 2xka FTSZ/TUBULIN-RELATED
PROTEIN
(Bacillus
thuringiensis) 		5 / 12 PRO A  89
GLY A 140
GLY A 139
ASP A  94
LEU A 152
 None
GSP  A 900 (-3.3A)
GSP  A 900 (-3.3A)
None
None
 1.02A 3m6vB-2xkaA:
3.0		 3m6vB-2xkaA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3M6W_A_SAMA465_0
(RRNA METHYLASE)		 2xka FTSZ/TUBULIN-RELATED
PROTEIN
(Bacillus
thuringiensis) 		5 / 12 PRO A  89
GLY A 140
GLY A 139
ASP A  94
LEU A 152
 None
GSP  A 900 (-3.3A)
GSP  A 900 (-3.3A)
None
None
 1.01A 3m6wA-2xkaA:
undetectable		 3m6wA-2xkaA:
22.54
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDV_B_AICB376_1
(BETA-PEPTIDYL
AMINOPEPTIDASE)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 11 LEU A 153
GLY A 146
LEU A  67
ASN A  15
LEU A  69
 None
GSP  A2466 (-4.0A)
None
None
None
 1.16A 3ndvA-1z5vA:
0.0
3ndvB-1z5vA:
0.0		 3ndvA-1z5vA:
19.39
3ndvB-1z5vA:
19.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ONN_A_ACTA271_0
(PROTEIN SSM1)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		4 / 5 GLY A 103
GLU A 136
GLY A 101
PRO A 132
 GSP  A 401 ( 4.4A)
GSP  A 401 (-2.7A)
GSP  A 401 (-3.3A)
GSP  A 401 (-4.3A)
 1.02A 3onnA-2q1yA:
6.6		 3onnA-2q1yA:
20.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3OU6_D_SAMD300_0
(SAM-DEPENDENT
METHYLTRANSFERASE)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 12 GLU A 102
ALA A 100
GLY A  19
ASP A 184
LEU A 187
 None
None
GSP  A 401 (-3.6A)
GSP  A 401 (-3.1A)
None
 1.43A 3ou6D-2q1yA:
3.1		 3ou6D-2q1yA:
21.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 1tnd TRANSDUCIN
(Bos
taurus) 		4 / 6 SER A  40
SER A  43
GLY A 199
GLY A  36
 GSP  A 351 (-3.2A)
MG  A 352 ( 2.2A)
GSP  A 351 (-3.6A)
None
 0.71A 3rxfA-1tndA:
undetectable		 3rxfA-1tndA:
20.80
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		4 / 6 SER A  49
SER A  52
GLY A 221
GLY A  45
 GSP  A1382 (-3.4A)
MG  A1381 ( 2.0A)
GSP  A1382 (-3.4A)
None
 0.63A 3rxfA-2xtzA:
undetectable		 3rxfA-2xtzA:
20.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 1yr7 ATP(GTP)BINDING
PROTEIN
(Pyrococcus
abyssi) 		3 / 3 GLY A  10
GLY A  12
THR A  14
 GSP  A 401 (-3.7A)
GSP  A 401 (-2.9A)
GSP  A 401 (-2.6A)
 0.44A 3si7B-1yr7A:
undetectable		 3si7B-1yr7A:
22.30
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SI7_B_ACTB4_0
(CYSTIC FIBROSIS
TRANSMEMBRANE
CONDUCTANCE
REGULATOR)		 2hf8 PROBABLE HYDROGENASE
NICKEL INCORPORATION
PROTEIN HYPB
(Methanocaldococc
us
jannaschii) 		3 / 3 GLY A  43
GLY A  45
THR A  47
 GSP  A 300 (-3.1A)
GSP  A 300 (-3.2A)
MG  A 301 ( 3.1A)
 0.43A 3si7B-2hf8A:
3.1		 3si7B-2hf8A:
22.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3SO9_A_017A100_1
(HIV-1 PROTEASE)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 8 GLY A  67
ALA A  68
ASP A  71
GLY A 110
ILE A  16
 GSP  A 401 (-3.3A)
GSP  A 401 (-3.5A)
None
None
None
 1.32A 3so9A-2q1yA:
undetectable		 3so9A-2q1yA:
14.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3T7V_A_SAMA992_0
(METHYLORNITHINE
SYNTHASE PYLB)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 12 GLY A 108
GLY A  12
LEU A  86
GLN A  79
ALA A 118
 GSP  A1342 (-4.0A)
None
None
None
None
 0.98A 3t7vA-4b45A:
undetectable		 3t7vA-4b45A:
22.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4BLV_A_SAMA1281_0
(RIBOSOMAL RNA LARGE
SUBUNIT
METHYLTRANSFERASE J)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 12 LEU A 162
GLY A 102
GLY A   9
LEU A 133
GLY A 147
 None
GSP  A1342 ( 4.1A)
GSP  A1342 (-3.5A)
None
None
 1.17A 4blvA-4b45A:
undetectable		 4blvA-4b45A:
22.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_A_HCYA1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
 GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
 1.28A 4c49A-1z5vA:
undetectable		 4c49A-1z5vA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_B_HCYB1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
 GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
 1.28A 4c49B-1z5vA:
undetectable		 4c49B-1z5vA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_C_HCYC1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
 GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
 1.23A 4c49C-1z5vA:
undetectable		 4c49C-1z5vA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C49_D_HCYD1384_1
(CORTICOSTEROID-BINDI
NG GLOBULIN)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 SER A 140
VAL A 171
GLN A 230
ILE A 228
SER A 226
 GSP  A2466 (-3.1A)
None
None
GSP  A2466 (-4.5A)
None
 1.30A 4c49D-1z5vA:
undetectable		 4c49D-1z5vA:
21.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4C5N_D_UEGD300_1
(PHOSPHOMETHYLPYRIMID
INE KINASE)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 10 GLY A 106
ALA A  72
GLY A 110
VAL A  64
VAL A   8
 GSP  A1342 (-3.9A)
None
None
GSP  A1342 ( 4.4A)
None
 1.31A 4c5nD-4b45A:
5.4		 4c5nD-4b45A:
23.25
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LNX_A_T3A502_1
(THYROID HORMONE
RECEPTOR ALPHA)		 4dvg RHO-LIKE SMALL
GTPASE
(Entamoeba
histolytica) 		5 / 12 ALA A  39
ALA A 164
SER A 166
LEU A  96
ILE A 162
 None
None
GSP  A 200 (-3.6A)
None
None
 1.16A 4lnxA-4dvgA:
undetectable		 4lnxA-4dvgA:
21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4N49_A_SAMA601_1
(CAP-SPECIFIC MRNA
(NUCLEOSIDE-2'-O-)-M
ETHYLTRANSFERASE 1)		 1tnd TRANSDUCIN
(Bos
taurus) 		4 / 4 ASN A 265
GLY A  41
ASP A 154
ASP A 146
 GSP  A 351 (-3.2A)
GSP  A 351 (-3.3A)
None
GSP  A 351 (-3.3A)
 1.31A 4n49A-1tndA:
undetectable		 4n49A-1tndA:
21.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4UCK_A_SAMA2409_0
(RNA-DIRECTED RNA
POLYMERASE L)		 1tnd TRANSDUCIN
(Bos
taurus) 		6 / 12 GLY A  41
GLY A  38
GLY A 199
SER A  40
ALA A 322
THR A 323
 GSP  A 351 (-3.3A)
GSP  A 351 ( 3.8A)
GSP  A 351 (-3.6A)
GSP  A 351 (-3.2A)
GSP  A 351 (-3.5A)
GSP  A 351 (-3.7A)
 1.42A 4uckA-1tndA:
undetectable		 4uckA-1tndA:
21.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XDR_A_ADNA402_1
(FAD:PROTEIN FMN
TRANSFERASE)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 12 LEU A 115
VAL A  99
GLY A 108
ILE A   6
VAL A  52
 None
None
GSP  A1342 (-4.0A)
None
None
 1.03A 4xdrA-4b45A:
undetectable		 4xdrA-4b45A:
25.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4YDQ_B_HFGB802_0
(PROLINE--TRNA LIGASE)		 5irr SEPTIN-LIKE PROTEIN
(Chlamydomonas
reinhardtii) 		5 / 12 PHE A 151
PRO A 147
THR A 146
HIS A 141
GLY A 122
 None
None
MG  A 401 ( 3.2A)
GSP  A 402 (-4.2A)
GSP  A 402 (-3.1A)
 1.21A 4ydqB-5irrA:
undetectable		 4ydqB-5irrA:
22.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4Z2E_H_TR6H101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
SYMMETRIZED E-SITE
DNA)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		3 / 5 GLY A 105
GLY A 103
GLU A 102
 GSP  A 401 (-3.6A)
GSP  A 401 ( 4.4A)
None
 0.35A 4z2eA-2q1yA:
undetectable
4z2eD-2q1yA:
3.3		 4z2eA-2q1yA:
22.18
4z2eD-2q1yA:
25.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZVM_A_DM2A303_1
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 1tnd TRANSDUCIN
(Bos
taurus) 		5 / 12 GLY A 199
GLY A 198
THR A 177
PHE A 219
ILE A 220
 GSP  A 351 (-3.6A)
GSP  A 351 (-3.6A)
MG  A 352 ( 3.3A)
None
None
 1.10A 4zvmA-1tndA:
6.4
4zvmB-1tndA:
6.8		 4zvmA-1tndA:
20.72
4zvmB-1tndA:
20.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_E_SAME301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 GLY A 148
GLY A 144
GLY A  11
LEU A  10
ALA A 105
 None
GSP  A2466 (-3.0A)
GSP  A2466 (-3.1A)
None
None
 0.91A 5c0oE-1z5vA:
2.9		 5c0oE-1z5vA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_G_SAMG301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 GLY A 148
GLY A 144
GLY A  11
LEU A  10
ALA A 105
 None
GSP  A2466 (-3.0A)
GSP  A2466 (-3.1A)
None
None
 0.90A 5c0oG-1z5vA:
2.1		 5c0oG-1z5vA:
19.07
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5C0O_H_SAMH301_0
(TRNA
(ADENINE(58)-N(1))-M
ETHYLTRANSFERASE
TRMI)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		5 / 12 GLY A   7
GLY A   9
SER A 107
GLY A 108
LEU A   5
 None
GSP  A1342 (-3.5A)
GSP  A1342 (-4.1A)
GSP  A1342 (-4.0A)
None
 1.03A 5c0oH-4b45A:
3.8		 5c0oH-4b45A:
23.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_A_TRPA101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeuA-2q1yA:
undetectable
5eeuB-2q1yA:
undetectable		 5eeuA-2q1yA:
12.94
5eeuB-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeuB-2q1yA:
undetectable
5eeuC-2q1yA:
undetectable		 5eeuB-2q1yA:
12.94
5eeuC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeuC-2q1yA:
undetectable
5eeuD-2q1yA:
undetectable		 5eeuC-2q1yA:
12.94
5eeuD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeuD-2q1yA:
undetectable
5eeuE-2q1yA:
undetectable		 5eeuD-2q1yA:
12.94
5eeuE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5eeuE-2q1yA:
undetectable
5eeuF-2q1yA:
undetectable		 5eeuE-2q1yA:
12.94
5eeuF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeuG-2q1yA:
undetectable
5eeuH-2q1yA:
undetectable		 5eeuG-2q1yA:
12.94
5eeuH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeuH-2q1yA:
undetectable
5eeuI-2q1yA:
undetectable		 5eeuH-2q1yA:
12.94
5eeuI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eeuJ-2q1yA:
undetectable
5eeuK-2q1yA:
undetectable		 5eeuJ-2q1yA:
12.94
5eeuK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eeuA-2q1yA:
undetectable
5eeuK-2q1yA:
undetectable		 5eeuA-2q1yA:
12.94
5eeuK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeuN-2q1yA:
undetectable
5eeuO-2q1yA:
undetectable		 5eeuN-2q1yA:
12.94
5eeuO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eeuP-2q1yA:
undetectable
5eeuQ-2q1yA:
undetectable		 5eeuP-2q1yA:
12.94
5eeuQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eeuR-2q1yA:
undetectable
5eeuS-2q1yA:
undetectable		 5eeuR-2q1yA:
12.94
5eeuS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eeuS-2q1yA:
undetectable
5eeuT-2q1yA:
undetectable		 5eeuS-2q1yA:
12.94
5eeuT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eeuT-2q1yA:
undetectable
5eeuU-2q1yA:
undetectable		 5eeuT-2q1yA:
12.94
5eeuU-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEU_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5eeuU-2q1yA:
undetectable
5eeuV-2q1yA:
undetectable		 5eeuU-2q1yA:
12.94
5eeuV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eevB-2q1yA:
undetectable
5eevC-2q1yA:
undetectable		 5eevB-2q1yA:
12.94
5eevC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eevC-2q1yA:
undetectable
5eevD-2q1yA:
undetectable		 5eevC-2q1yA:
12.94
5eevD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eevD-2q1yA:
undetectable
5eevE-2q1yA:
undetectable		 5eevD-2q1yA:
12.94
5eevE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5eevE-2q1yA:
undetectable
5eevF-2q1yA:
undetectable		 5eevE-2q1yA:
12.94
5eevF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eevG-2q1yA:
undetectable
5eevH-2q1yA:
undetectable		 5eevG-2q1yA:
12.94
5eevH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eevH-2q1yA:
undetectable
5eevI-2q1yA:
undetectable		 5eevH-2q1yA:
12.94
5eevI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eevJ-2q1yA:
undetectable
5eevK-2q1yA:
undetectable		 5eevJ-2q1yA:
12.94
5eevK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eevA-2q1yA:
undetectable
5eevK-2q1yA:
undetectable		 5eevA-2q1yA:
12.94
5eevK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eevN-2q1yA:
undetectable
5eevO-2q1yA:
undetectable		 5eevN-2q1yA:
12.94
5eevO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eevP-2q1yA:
undetectable
5eevQ-2q1yA:
undetectable		 5eevP-2q1yA:
12.94
5eevQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eevR-2q1yA:
undetectable
5eevS-2q1yA:
undetectable		 5eevR-2q1yA:
12.94
5eevS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eevS-2q1yA:
undetectable
5eevT-2q1yA:
undetectable		 5eevS-2q1yA:
12.94
5eevT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eevT-2q1yA:
undetectable
5eevU-2q1yA:
undetectable		 5eevT-2q1yA:
12.94
5eevU-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEV_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5eevU-2q1yA:
undetectable
5eevV-2q1yA:
undetectable		 5eevU-2q1yA:
12.94
5eevV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eewB-2q1yA:
undetectable
5eewC-2q1yA:
undetectable		 5eewB-2q1yA:
12.94
5eewC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eewC-2q1yA:
undetectable
5eewD-2q1yA:
undetectable		 5eewC-2q1yA:
12.94
5eewD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eewD-2q1yA:
undetectable
5eewE-2q1yA:
undetectable		 5eewD-2q1yA:
12.94
5eewE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5eewE-2q1yA:
undetectable
5eewF-2q1yA:
undetectable		 5eewE-2q1yA:
12.94
5eewF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eewG-2q1yA:
undetectable
5eewH-2q1yA:
undetectable		 5eewG-2q1yA:
12.94
5eewH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eewH-2q1yA:
undetectable
5eewI-2q1yA:
undetectable		 5eewH-2q1yA:
12.94
5eewI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eewJ-2q1yA:
undetectable
5eewK-2q1yA:
undetectable		 5eewJ-2q1yA:
12.94
5eewK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eewA-2q1yA:
undetectable
5eewK-2q1yA:
undetectable		 5eewA-2q1yA:
12.94
5eewK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eewN-2q1yA:
undetectable
5eewO-2q1yA:
undetectable		 5eewN-2q1yA:
12.94
5eewO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eewP-2q1yA:
undetectable
5eewQ-2q1yA:
undetectable		 5eewP-2q1yA:
12.94
5eewQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eewR-2q1yA:
undetectable
5eewS-2q1yA:
undetectable		 5eewR-2q1yA:
12.94
5eewS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eewS-2q1yA:
undetectable
5eewT-2q1yA:
undetectable		 5eewS-2q1yA:
12.94
5eewT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eewT-2q1yA:
undetectable
5eewU-2q1yA:
undetectable		 5eewT-2q1yA:
12.94
5eewU-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEW_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5eewU-2q1yA:
undetectable
5eewV-2q1yA:
undetectable		 5eewU-2q1yA:
12.94
5eewV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eexB-2q1yA:
undetectable
5eexC-2q1yA:
undetectable		 5eexB-2q1yA:
12.94
5eexC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eexC-2q1yA:
undetectable
5eexD-2q1yA:
undetectable		 5eexC-2q1yA:
12.94
5eexD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eexD-2q1yA:
undetectable
5eexE-2q1yA:
undetectable		 5eexD-2q1yA:
12.94
5eexE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5eexE-2q1yA:
undetectable
5eexF-2q1yA:
undetectable		 5eexE-2q1yA:
12.94
5eexF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eexG-2q1yA:
undetectable
5eexH-2q1yA:
undetectable		 5eexG-2q1yA:
12.94
5eexH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eexH-2q1yA:
undetectable
5eexI-2q1yA:
undetectable		 5eexH-2q1yA:
12.94
5eexI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 5eexI-2q1yA:
undetectable
5eexJ-2q1yA:
undetectable		 5eexI-2q1yA:
12.94
5eexJ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eexJ-2q1yA:
undetectable
5eexK-2q1yA:
undetectable		 5eexJ-2q1yA:
12.94
5eexK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eexA-2q1yA:
undetectable
5eexK-2q1yA:
undetectable		 5eexA-2q1yA:
12.94
5eexK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eexN-2q1yA:
undetectable
5eexO-2q1yA:
undetectable		 5eexN-2q1yA:
12.94
5eexO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eexP-2q1yA:
undetectable
5eexQ-2q1yA:
undetectable		 5eexP-2q1yA:
12.94
5eexQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eexQ-2q1yA:
undetectable
5eexR-2q1yA:
undetectable		 5eexQ-2q1yA:
12.94
5eexR-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eexR-2q1yA:
undetectable
5eexS-2q1yA:
undetectable		 5eexR-2q1yA:
12.94
5eexS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eexS-2q1yA:
undetectable
5eexT-2q1yA:
undetectable		 5eexS-2q1yA:
12.94
5eexT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eexT-2q1yA:
undetectable
5eexU-2q1yA:
undetectable		 5eexT-2q1yA:
12.94
5eexU-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEX_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5eexU-2q1yA:
undetectable
5eexV-2q1yA:
undetectable		 5eexU-2q1yA:
12.94
5eexV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyB-2q1yA:
undetectable
5eeyC-2q1yA:
undetectable		 5eeyB-2q1yA:
12.94
5eeyC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyC-2q1yA:
undetectable
5eeyD-2q1yA:
undetectable		 5eeyC-2q1yA:
12.94
5eeyD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eeyD-2q1yA:
undetectable
5eeyE-2q1yA:
undetectable		 5eeyD-2q1yA:
12.94
5eeyE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5eeyE-2q1yA:
undetectable
5eeyF-2q1yA:
undetectable		 5eeyE-2q1yA:
12.94
5eeyF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyG-2q1yA:
undetectable
5eeyH-2q1yA:
undetectable		 5eeyG-2q1yA:
12.94
5eeyH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyH-2q1yA:
undetectable
5eeyI-2q1yA:
undetectable		 5eeyH-2q1yA:
12.94
5eeyI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 5eeyI-2q1yA:
undetectable
5eeyJ-2q1yA:
undetectable		 5eeyI-2q1yA:
12.94
5eeyJ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eeyJ-2q1yA:
undetectable
5eeyK-2q1yA:
undetectable		 5eeyJ-2q1yA:
12.94
5eeyK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyA-2q1yA:
undetectable
5eeyK-2q1yA:
undetectable		 5eeyA-2q1yA:
12.94
5eeyK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyN-2q1yA:
undetectable
5eeyO-2q1yA:
undetectable		 5eeyN-2q1yA:
12.94
5eeyO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyP-2q1yA:
undetectable
5eeyQ-2q1yA:
undetectable		 5eeyP-2q1yA:
12.94
5eeyQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eeyQ-2q1yA:
undetectable
5eeyR-2q1yA:
undetectable		 5eeyQ-2q1yA:
12.94
5eeyR-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eeyR-2q1yA:
undetectable
5eeyS-2q1yA:
undetectable		 5eeyR-2q1yA:
12.94
5eeyS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eeyS-2q1yA:
undetectable
5eeyT-2q1yA:
undetectable		 5eeyS-2q1yA:
12.94
5eeyT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eeyT-2q1yA:
undetectable
5eeyU-2q1yA:
undetectable		 5eeyT-2q1yA:
12.94
5eeyU-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEY_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5eeyU-2q1yA:
undetectable
5eeyV-2q1yA:
undetectable		 5eeyU-2q1yA:
12.94
5eeyV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eezB-2q1yA:
undetectable
5eezC-2q1yA:
undetectable		 5eezB-2q1yA:
12.94
5eezC-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eezC-2q1yA:
undetectable
5eezD-2q1yA:
undetectable		 5eezC-2q1yA:
12.94
5eezD-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eezD-2q1yA:
undetectable
5eezE-2q1yA:
undetectable		 5eezD-2q1yA:
12.94
5eezE-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5eezE-2q1yA:
undetectable
5eezF-2q1yA:
undetectable		 5eezE-2q1yA:
12.94
5eezF-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eezG-2q1yA:
undetectable
5eezH-2q1yA:
undetectable		 5eezG-2q1yA:
12.94
5eezH-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eezH-2q1yA:
undetectable
5eezI-2q1yA:
undetectable		 5eezH-2q1yA:
12.94
5eezI-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 5eezI-2q1yA:
undetectable
5eezJ-2q1yA:
undetectable		 5eezI-2q1yA:
12.94
5eezJ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5eezJ-2q1yA:
undetectable
5eezK-2q1yA:
undetectable		 5eezJ-2q1yA:
12.94
5eezK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eezA-2q1yA:
undetectable
5eezK-2q1yA:
undetectable		 5eezA-2q1yA:
12.94
5eezK-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eezN-2q1yA:
undetectable
5eezO-2q1yA:
undetectable		 5eezN-2q1yA:
12.94
5eezO-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eezP-2q1yA:
undetectable
5eezQ-2q1yA:
undetectable		 5eezP-2q1yA:
12.94
5eezQ-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5eezQ-2q1yA:
undetectable
5eezR-2q1yA:
undetectable		 5eezQ-2q1yA:
12.94
5eezR-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eezR-2q1yA:
undetectable
5eezS-2q1yA:
undetectable		 5eezR-2q1yA:
12.94
5eezS-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5eezS-2q1yA:
undetectable
5eezT-2q1yA:
undetectable		 5eezS-2q1yA:
12.94
5eezT-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5eezT-2q1yA:
undetectable
5eezU-2q1yA:
undetectable		 5eezT-2q1yA:
12.94
5eezU-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EEZ_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5eezU-2q1yA:
undetectable
5eezV-2q1yA:
undetectable		 5eezU-2q1yA:
12.94
5eezV-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0B-2q1yA:
undetectable
5ef0C-2q1yA:
undetectable		 5ef0B-2q1yA:
12.94
5ef0C-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0C-2q1yA:
undetectable
5ef0D-2q1yA:
undetectable		 5ef0C-2q1yA:
12.94
5ef0D-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef0D-2q1yA:
undetectable
5ef0E-2q1yA:
undetectable		 5ef0D-2q1yA:
12.94
5ef0E-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5ef0E-2q1yA:
undetectable
5ef0F-2q1yA:
undetectable		 5ef0E-2q1yA:
12.94
5ef0F-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0G-2q1yA:
undetectable
5ef0H-2q1yA:
undetectable		 5ef0G-2q1yA:
12.94
5ef0H-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0H-2q1yA:
undetectable
5ef0I-2q1yA:
undetectable		 5ef0H-2q1yA:
12.94
5ef0I-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 5ef0I-2q1yA:
undetectable
5ef0J-2q1yA:
undetectable		 5ef0I-2q1yA:
12.94
5ef0J-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef0J-2q1yA:
undetectable
5ef0K-2q1yA:
undetectable		 5ef0J-2q1yA:
12.94
5ef0K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0A-2q1yA:
undetectable
5ef0K-2q1yA:
undetectable		 5ef0A-2q1yA:
12.94
5ef0K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0N-2q1yA:
undetectable
5ef0O-2q1yA:
undetectable		 5ef0N-2q1yA:
12.94
5ef0O-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0P-2q1yA:
undetectable
5ef0Q-2q1yA:
undetectable		 5ef0P-2q1yA:
12.94
5ef0Q-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef0Q-2q1yA:
undetectable
5ef0R-2q1yA:
undetectable		 5ef0Q-2q1yA:
12.94
5ef0R-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef0R-2q1yA:
undetectable
5ef0S-2q1yA:
undetectable		 5ef0R-2q1yA:
12.94
5ef0S-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef0S-2q1yA:
undetectable
5ef0T-2q1yA:
undetectable		 5ef0S-2q1yA:
12.94
5ef0T-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef0T-2q1yA:
undetectable
5ef0U-2q1yA:
undetectable		 5ef0T-2q1yA:
12.94
5ef0U-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF0_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5ef0U-2q1yA:
undetectable
5ef0V-2q1yA:
undetectable		 5ef0U-2q1yA:
12.94
5ef0V-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1B-2q1yA:
undetectable
5ef1C-2q1yA:
undetectable		 5ef1B-2q1yA:
12.94
5ef1C-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1C-2q1yA:
undetectable
5ef1D-2q1yA:
undetectable		 5ef1C-2q1yA:
12.94
5ef1D-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef1D-2q1yA:
undetectable
5ef1E-2q1yA:
undetectable		 5ef1D-2q1yA:
12.94
5ef1E-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5ef1E-2q1yA:
undetectable
5ef1F-2q1yA:
undetectable		 5ef1E-2q1yA:
12.94
5ef1F-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1G-2q1yA:
undetectable
5ef1H-2q1yA:
undetectable		 5ef1G-2q1yA:
12.94
5ef1H-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1H-2q1yA:
undetectable
5ef1I-2q1yA:
undetectable		 5ef1H-2q1yA:
12.94
5ef1I-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 5ef1I-2q1yA:
undetectable
5ef1J-2q1yA:
undetectable		 5ef1I-2q1yA:
12.94
5ef1J-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef1J-2q1yA:
undetectable
5ef1K-2q1yA:
undetectable		 5ef1J-2q1yA:
12.94
5ef1K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1A-2q1yA:
undetectable
5ef1K-2q1yA:
undetectable		 5ef1A-2q1yA:
12.94
5ef1K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1N-2q1yA:
undetectable
5ef1O-2q1yA:
undetectable		 5ef1N-2q1yA:
12.94
5ef1O-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1P-2q1yA:
undetectable
5ef1Q-2q1yA:
undetectable		 5ef1P-2q1yA:
12.94
5ef1Q-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef1Q-2q1yA:
undetectable
5ef1R-2q1yA:
undetectable		 5ef1Q-2q1yA:
12.94
5ef1R-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef1R-2q1yA:
undetectable
5ef1S-2q1yA:
undetectable		 5ef1R-2q1yA:
12.94
5ef1S-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef1S-2q1yA:
undetectable
5ef1T-2q1yA:
undetectable		 5ef1S-2q1yA:
12.94
5ef1T-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef1T-2q1yA:
undetectable
5ef1U-2q1yA:
undetectable		 5ef1T-2q1yA:
12.94
5ef1U-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF1_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5ef1U-2q1yA:
undetectable
5ef1V-2q1yA:
undetectable		 5ef1U-2q1yA:
12.94
5ef1V-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef2B-2q1yA:
undetectable
5ef2C-2q1yA:
undetectable		 5ef2B-2q1yA:
12.94
5ef2C-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef2C-2q1yA:
undetectable
5ef2D-2q1yA:
undetectable		 5ef2C-2q1yA:
12.94
5ef2D-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef2D-2q1yA:
undetectable
5ef2E-2q1yA:
undetectable		 5ef2D-2q1yA:
12.94
5ef2E-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5ef2E-2q1yA:
undetectable
5ef2F-2q1yA:
undetectable		 5ef2E-2q1yA:
12.94
5ef2F-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef2G-2q1yA:
undetectable
5ef2H-2q1yA:
undetectable		 5ef2G-2q1yA:
12.94
5ef2H-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef2H-2q1yA:
undetectable
5ef2I-2q1yA:
undetectable		 5ef2H-2q1yA:
12.94
5ef2I-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 5ef2I-2q1yA:
undetectable
5ef2J-2q1yA:
undetectable		 5ef2I-2q1yA:
12.94
5ef2J-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5ef2J-2q1yA:
undetectable
5ef2K-2q1yA:
undetectable		 5ef2J-2q1yA:
12.94
5ef2K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef2A-2q1yA:
undetectable
5ef2K-2q1yA:
undetectable		 5ef2A-2q1yA:
12.94
5ef2K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef2N-2q1yA:
undetectable
5ef2O-2q1yA:
undetectable		 5ef2N-2q1yA:
12.94
5ef2O-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef2P-2q1yA:
undetectable
5ef2Q-2q1yA:
undetectable		 5ef2P-2q1yA:
12.94
5ef2Q-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef2Q-2q1yA:
undetectable
5ef2R-2q1yA:
undetectable		 5ef2Q-2q1yA:
12.94
5ef2R-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef2R-2q1yA:
undetectable
5ef2S-2q1yA:
undetectable		 5ef2R-2q1yA:
12.94
5ef2S-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef2S-2q1yA:
undetectable
5ef2T-2q1yA:
undetectable		 5ef2S-2q1yA:
12.94
5ef2T-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef2T-2q1yA:
undetectable
5ef2U-2q1yA:
undetectable		 5ef2T-2q1yA:
12.94
5ef2U-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF2_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5ef2U-2q1yA:
undetectable
5ef2V-2q1yA:
undetectable		 5ef2U-2q1yA:
12.94
5ef2V-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_B_TRPB101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef3B-2q1yA:
undetectable
5ef3C-2q1yA:
undetectable		 5ef3B-2q1yA:
12.94
5ef3C-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_C_TRPC101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef3C-2q1yA:
undetectable
5ef3D-2q1yA:
undetectable		 5ef3C-2q1yA:
12.94
5ef3D-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_D_TRPD101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef3D-2q1yA:
undetectable
5ef3E-2q1yA:
undetectable		 5ef3D-2q1yA:
12.94
5ef3E-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_E_TRPE101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.31A 5ef3E-2q1yA:
undetectable
5ef3F-2q1yA:
undetectable		 5ef3E-2q1yA:
12.94
5ef3F-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_G_TRPG101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef3G-2q1yA:
undetectable
5ef3H-2q1yA:
undetectable		 5ef3G-2q1yA:
12.94
5ef3H-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_H_TRPH101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef3H-2q1yA:
undetectable
5ef3I-2q1yA:
undetectable		 5ef3H-2q1yA:
12.94
5ef3I-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_I_TRPI101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 11 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.36A 5ef3I-2q1yA:
undetectable
5ef3J-2q1yA:
undetectable		 5ef3I-2q1yA:
12.94
5ef3J-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_J_TRPJ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef3J-2q1yA:
undetectable
5ef3K-2q1yA:
undetectable		 5ef3J-2q1yA:
12.94
5ef3K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_K_TRPK101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef3A-2q1yA:
undetectable
5ef3K-2q1yA:
undetectable		 5ef3A-2q1yA:
12.94
5ef3K-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_O_TRPO101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef3N-2q1yA:
undetectable
5ef3O-2q1yA:
undetectable		 5ef3N-2q1yA:
12.94
5ef3O-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_Q_TRPQ101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef3P-2q1yA:
undetectable
5ef3Q-2q1yA:
undetectable		 5ef3P-2q1yA:
12.94
5ef3Q-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_R_TRPR101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 9 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.33A 5ef3Q-2q1yA:
undetectable
5ef3R-2q1yA:
undetectable		 5ef3Q-2q1yA:
12.94
5ef3R-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_S_TRPS101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef3R-2q1yA:
undetectable
5ef3S-2q1yA:
undetectable		 5ef3R-2q1yA:
12.94
5ef3S-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_T_TRPT101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.34A 5ef3S-2q1yA:
undetectable
5ef3T-2q1yA:
undetectable		 5ef3S-2q1yA:
12.94
5ef3T-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_U_TRPU101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.32A 5ef3T-2q1yA:
undetectable
5ef3U-2q1yA:
undetectable		 5ef3T-2q1yA:
12.94
5ef3U-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EF3_V_TRPV101_0
(TRANSCRIPTION
ATTENUATION PROTEIN
MTRB)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 10 GLY A 107
ALA A  79
THR A  42
THR A 106
ILE A  16
 GSP  A 401 (-3.6A)
None
GSP  A 401 (-4.5A)
GSP  A 401 (-3.6A)
None
 1.35A 5ef3U-2q1yA:
undetectable
5ef3V-2q1yA:
undetectable		 5ef3U-2q1yA:
12.94
5ef3V-2q1yA:
12.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_A_SAMA4001_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 107
GLY A 104
GLY A  69
THR A 108
ILE A  16
 GSP  A 401 (-3.6A)
GSP  A 401 (-3.6A)
GSP  A 401 (-3.8A)
None
None
 1.01A 5ehiA-2q1yA:
undetectable		 5ehiA-2q1yA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EHI_C_SAMC4000_0
(NS5
METHYLTRANSFERASE
DENGUE VIRUS)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 107
GLY A 104
GLY A  69
THR A 108
ILE A  16
 GSP  A 401 (-3.6A)
GSP  A 401 (-3.6A)
GSP  A 401 (-3.8A)
None
None
 1.06A 5ehiC-2q1yA:
undetectable		 5ehiC-2q1yA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EIW_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 107
GLY A 104
GLY A  69
THR A 108
ILE A  16
 GSP  A 401 (-3.6A)
GSP  A 401 (-3.6A)
GSP  A 401 (-3.8A)
None
None
 1.02A 5eiwA-2q1yA:
undetectable		 5eiwA-2q1yA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EKX_A_SAMA301_0
(NS5
METHYLTRANSFERASE)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		5 / 12 GLY A 107
GLY A 104
GLY A  69
THR A 108
ILE A  16
 GSP  A 401 (-3.6A)
GSP  A 401 (-3.6A)
GSP  A 401 (-3.8A)
None
None
 1.00A 5ekxA-2q1yA:
undetectable		 5ekxA-2q1yA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5GLM_A_ACTA613_0
(GLYCOSIDE HYDROLASE
FAMILY 43)		 1yr7 ATP(GTP)BINDING
PROTEIN
(Pyrococcus
abyssi) 		3 / 3 ASP A  36
SER A  73
TYR A  74
 GSP  A 401 (-4.6A)
None
None
 0.79A 5glmA-1yr7A:
undetectable		 5glmA-1yr7A:
23.36
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HG0_A_SAMA301_0
(PANTOTHENATE
SYNTHETASE)		 2xtz GUANINE
NUCLEOTIDE-BINDING
PROTEIN ALPHA-1
SUBUNIT
(Arabidopsis
thaliana) 		5 / 12 GLY A  47
VAL A 236
GLY A 220
ASP A 218
GLN A 222
 GSP  A1382 (-3.6A)
None
GSP  A1382 (-3.8A)
MG  A1381 ( 3.8A)
GSP  A1382 ( 4.6A)
 1.20A 5hg0A-2xtzA:
undetectable		 5hg0A-2xtzA:
22.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IK1_A_CAMA502_0
(CAMPHOR
5-MONOOXYGENASE)		 2hf8 PROBABLE HYDROGENASE
NICKEL INCORPORATION
PROTEIN HYPB
(Methanocaldococc
us
jannaschii) 		4 / 5 LEU A  48
GLY A  45
ASP A 170
ILE A 169
 GSP  A 300 (-4.3A)
GSP  A 300 (-3.2A)
GSP  A 300 (-2.9A)
None
 0.89A 5ik1A-2hf8A:
undetectable		 5ik1A-2hf8A:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5J4N_B_AG2B501_1
(ARGININE/AGMATINE
ANTIPORTER)		 2q1y CELL DIVISION
PROTEIN FTSZ
(Mycobacterium
tuberculosis) 		4 / 6 ILE A  38
GLY A  19
ASN A  22
ILE A  16
 None
GSP  A 401 (-3.6A)
GSP  A 401 (-3.8A)
None
 0.97A 5j4nB-2q1yA:
undetectable		 5j4nB-2q1yA:
23.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_A_SAMA501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 1z5v TUBULIN GAMMA-1
CHAIN
(Homo
sapiens) 		5 / 12 LEU A 149
GLY A  11
LEU A 153
LEU A 157
LEU A   8
 None
GSP  A2466 (-3.1A)
None
None
None
 0.98A 5nfjA-1z5vA:
2.6		 5nfjA-1z5vA:
16.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NWU_A_ACAA18_1
(WTFP-TAG,GP41)		 4tmz EIF5B
(Chaetomium
thermophilum) 		5 / 12 ALA B 562
GLY B 561
ASN B 547
GLN B 549
GLU B 550
 None
None
None
GSP  B 901 (-3.9A)
None
 1.20A 5nwuA-4tmzB:
undetectable		 5nwuA-4tmzB:
8.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X5Q_E_D16E402_1
(THYMIDYLATE SYNTHASE)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		4 / 6 PHE A  98
LEU A  15
GLY A  12
TYR A 179
 None
None
None
GSP  A1342 (-3.8A)
 0.89A 5x5qE-4b45A:
undetectable		 5x5qE-4b45A:
23.97
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X80_D_SALD201_1
(UNCHARACTERIZED
HTH-TYPE
TRANSCRIPTIONAL
REGULATOR RV2887)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		4 / 5 PRO A 134
GLY A 104
TYR A 142
VAL A 144
 GSP  A1342 ( 4.4A)
GSP  A1342 ( 4.6A)
None
None
 1.24A 5x80C-4b45A:
undetectable
5x80D-4b45A:
undetectable		 5x80C-4b45A:
22.51
5x80D-4b45A:
22.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6C79_A_CE3A301_1
(BETA-LACTAMASE
TOHO-1)		 4b45 CELL DIVISION
PROTEIN FTSZ
(Haloferax
volcanii) 		6 / 12 ALA A 112
THR A 152
GLY A 110
SER A 109
GLY A 105
ASN A 145
 None
None
None
None
GSP  A1342 (-3.4A)
None
 1.44A 6c79A-4b45A:
undetectable		 6c79A-4b45A:
13.86