SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GSF'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1QCA_A_FUAA221_1 (TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE)	4png	LD04004P (Drosophila melanogaster)	4 / 7	PHE A 174 SER A 166 PHE A 209 PHE A 108	None None None GSF A2001 (-3.8A)	1.01A	1qcaA-4pngA: undetectable	1qcaA-4pngA: 23.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BJW_F_SVRF502_2 (PHOSPHOLIPASE A2)	4png	LD04004P (Drosophila melanogaster)	4 / 5	ILE A 165 SER A 166 PHE A 108 PRO A 14	None None GSF A2001 (-3.8A) GSF A2001 (-4.6A)	1.35A	3bjwC-4pngA: undetectable	3bjwC-4pngA: 18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4G5J_A_0WMA1102_1 (EPIDERMAL GROWTH FACTOR RECEPTOR)	4png	LD04004P (Drosophila melanogaster)	4 / 7	PHE A 108 HIS A 69 ILE A 72 PRO A 14	GSF A2001 (-3.8A) GSF A2001 (-3.9A) None GSF A2001 (-4.6A)	1.18A	4g5jA-4pngA: undetectable	4g5jA-4pngA: 22.09
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IJI_F_BEZF501_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN YIBF)	4mk3	GLUTATHIONE S-TRANSFERASE (Cupriavidus metallidurans)	4 / 8	SER A 9 ARG A 108 TYR A 166 ARG A 170	GSF A 304 (-2.4A) None None None	0.56A	4ijiF-4mk3A: 27.6	4ijiF-4mk3A: 35.06
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	4IJI_H_BEZH501_0 (GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN YIBF)	4mk3	GLUTATHIONE S-TRANSFERASE (Cupriavidus metallidurans)	4 / 7	SER A 9 ARG A 108 TYR A 166 ARG A 170	GSF A 304 (-2.4A) None None None	0.58A	4ijiH-4mk3A: 27.0	4ijiH-4mk3A: 35.06

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1QCA_A_FUAA221_1","TYPE III CHLORAMPHENICOL ACETYLTRANSFERASE","4png","LD04004P","Drosophila melanogaster",4,"PHE A 174;SER A 166;PHE A 209;PHE A 108","None;None;None;GSF A2001 (-3.8A)","1.01A","1qcaA-4pngA:undetectable",null],["3BJW_F_SVRF502_2","PHOSPHOLIPASE A2;PHOSPHOLIPASE A2","4png","LD04004P","Drosophila melanogaster",4,"ILE A 165;SER A 166;PHE A 108;PRO A  14","None;None;GSF A2001 (-3.8A);GSF A2001 (-4.6A)","1.35A","3bjwC-4pngA:undetectable","1qcaA-4pngA:23.20"],["4G5J_A_0WMA1102_1","EPIDERMAL GROWTH FACTOR RECEPTOR","4png","LD04004P","Drosophila melanogaster",4,"PHE A 108;HIS A  69;ILE A  72;PRO A  14","GSF A2001 (-3.8A);GSF A2001 (-3.9A);None;GSF A2001 (-4.6A)","1.18A","4g5jA-4pngA:undetectable","3bjwC-4pngA:18.39"],["4IJI_F_BEZF501_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN YIBF","4mk3","GLUTATHIONE S-TRANSFERASE","Cupriavidus metallidurans",4,"SER A   9;ARG A 108;TYR A 166;ARG A 170","GSF A 304 (-2.4A);None;None;None","0.56A","4ijiF-4mk3A:27.6","4g5jA-4pngA:22.09"],["4IJI_H_BEZH501_0","GLUTATHIONE S-TRANSFERASE-LIKE PROTEIN YIBF","4mk3","GLUTATHIONE S-TRANSFERASE","Cupriavidus metallidurans",4,"SER A   9;ARG A 108;TYR A 166;ARG A 170","GSF A 304 (-2.4A);None;None;None","0.58A","4ijiH-4mk3A:27.0","4ijiF-4mk3A:35.06"]]