SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GP9'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CDQ_B_SAMB1500_0 (ASPARTOKINASE)	2w5s	PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE (Staphylococcus aureus)	4 / 7	SER A 408 ASP A 344 ARG A 356 GLU A 304	None None GP9 A1644 (-3.0A) None	0.96A	2cdqB-2w5sA: undetectable	2cdqB-2w5sA: 22.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O7G_A_ASCA303_0 (PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2)	2w5s	PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE (Staphylococcus aureus)	4 / 7	HIS A 409 ILE A 411 TYR A 360 ARG A 356	None None None GP9 A1644 (-3.0A)	1.31A	4o7gA-2w5sA: undetectable 4o7gB-2w5sA: undetectable	4o7gA-2w5sA: 18.78 4o7gB-2w5sA: 18.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6EXI_A_ADNA502_0 (ADENOSYLHOMOCYSTEINA SE)	2w5s	PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE (Staphylococcus aureus)	5 / 12	HIS A 416 THR A 420 ASP A 388 LEU A 384 GLY A 385	GP9 A1644 (-4.0A) None None None None	1.48A	6exiA-2w5sA: undetectable	6exiA-2w5sA: 17.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6GNE_A_ACRA602_2 (-)	2w5s	PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE (Staphylococcus aureus)	4 / 6	TYR A 477 HIS A 416 ASN A 415 TYR A 441	None GP9 A1644 (-4.0A) None None	1.37A	6gneA-2w5sA: 2.1	6gneA-2w5sA: 21.78

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CDQ_B_SAMB1500_0","ASPARTOKINASE","2w5s","PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE","Staphylococcus aureus",4,"SER A 408;ASP A 344;ARG A 356;GLU A 304","None;None;GP9 A1644 (-3.0A);None","0.96A","2cdqB-2w5sA:undetectable",null],["4O7G_A_ASCA303_0","PROBABLE TRANSMEMBRANE ASCORBATE FERRIREDUCTASE 2","2w5s","PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE","Staphylococcus aureus",4,"HIS A 409;ILE A 411;TYR A 360;ARG A 356","None;None;None;GP9 A1644 (-3.0A)","1.31A","4o7gA-2w5sA:undetectable;4o7gB-2w5sA:undetectable","2cdqB-2w5sA:22.99"],["6EXI_A_ADNA502_0","ADENOSYLHOMOCYSTEINASE","2w5s","PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE","Staphylococcus aureus",5,"HIS A 416;THR A 420;ASP A 388;LEU A 384;GLY A 385","GP9 A1644 (-4.0A);None;None;None;None","1.48A","6exiA-2w5sA:undetectable","4o7gA-2w5sA:18.78;4o7gB-2w5sA:18.78"],["6GNE_A_ACRA602_2","-","2w5s","PROCESSED GLYCEROL PHOSPHATE LIPOTEICHOIC ACID SYNTHASE","Staphylococcus aureus",4,"TYR A 477;HIS A 416;ASN A 415;TYR A 441","None;GP9 A1644 (-4.0A);None;None","1.37A","6gneA-2w5sA:2.1","6exiA-2w5sA:17.46"]]