SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GNS'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2JIH_A_097A1001_1
(ADAMTS-1)		 5t03 MALTOSE BINDING
PROTEIN - HEPARAN
SULFATE
6-O-SULFOTRANSFERASE
ISOFORM 3 FUSION
PROTEIN
(Danio
rerio;
Escherichia
coli) 		5 / 9 LEU A1260
HIS A1158
HIS A1101
MET A1189
LEU A1190
 None
GNS  A1402 ( 3.9A)
A3P  A1401 (-3.9A)
None
None
 1.32A 2jihA-5t03A:
undetectable		 2jihA-5t03A:
17.74