SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GLD'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

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	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	1ua7	ALPHA-AMYLASE (Bacillus subtilis)	6 / 12	TYR A 62 LEU A 141 LEU A 142 ASP A 176 ALA A 177 HIS A 268	ACI A 504 ( 3.7A) G6D A 505 ( 4.7A) GLD A 502 (-4.1A) ACI A 504 (-3.0A) G6D A 505 (-3.4A) ACI A 504 (-3.8A)	1.47A	1dedA-1ua7A: 30.9	1dedA-1ua7A: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	1ua7	ALPHA-AMYLASE (Bacillus subtilis)	7 / 12	TYR A 62 LEU A 141 LEU A 144 ASP A 176 ALA A 177 HIS A 268 ASP A 269	ACI A 504 ( 3.7A) G6D A 505 ( 4.7A) GLD A 502 ( 4.8A) ACI A 504 (-3.0A) G6D A 505 (-3.4A) ACI A 504 (-3.8A) ACI A 504 ( 2.8A)	0.59A	1dedA-1ua7A: 30.9	1dedA-1ua7A: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	LEU A 315 ASP A 350 ALA A 351 HIS A 446 ASP A 447 ARG A 450	None ACI A 806 (-3.1A) GLD A 807 (-3.6A) ACI A 806 (-4.1A) ACI A 806 (-2.9A) GLC A 805 (-3.1A)	1.10A	1dedA-3bc9A: 27.1	1dedA-3bc9A: 24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_A_QPSA1001_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	TYR A 184 LEU A 315 ASP A 350 ALA A 351 HIS A 446 ASP A 447	ACI A 806 ( 4.0A) None ACI A 806 (-3.1A) GLD A 807 (-3.6A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.70A	1dedA-3bc9A: 27.1	1dedA-3bc9A: 24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_B_QPSB1501_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	1ua7	ALPHA-AMYLASE (Bacillus subtilis)	7 / 12	TYR A 62 LEU A 142 ARG A 174 ASP A 176 ALA A 177 GLU A 208 HIS A 268	ACI A 504 ( 3.7A) GLD A 502 (-4.1A) ACI A 504 (-3.5A) ACI A 504 (-3.0A) G6D A 505 (-3.4A) ACI A 504 ( 2.9A) ACI A 504 (-3.8A)	1.27A	1dedB-1ua7A: 28.5	1dedB-1ua7A: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_B_QPSB1501_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	1ua7	ALPHA-AMYLASE (Bacillus subtilis)	8 / 12	TYR A 62 LEU A 144 ARG A 174 ASP A 176 ALA A 177 GLU A 208 HIS A 268 ASP A 269	ACI A 504 ( 3.7A) GLD A 502 ( 4.8A) ACI A 504 (-3.5A) ACI A 504 (-3.0A) G6D A 505 (-3.4A) ACI A 504 ( 2.9A) ACI A 504 (-3.8A) ACI A 504 ( 2.8A)	0.64A	1dedB-1ua7A: 28.5	1dedB-1ua7A: 23.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_B_QPSB1501_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	TYR A 184 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ARG A 450	ACI A 806 ( 4.0A) ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) GLC A 805 (-3.1A)	1.03A	1dedB-3bc9A: 24.4	1dedB-3bc9A: 24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1DED_B_QPSB1501_1 (CYCLODEXTRIN GLUCANOTRANSFERASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	TYR A 184 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	ACI A 806 ( 4.0A) ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.71A	1dedB-3bc9A: 24.4	1dedB-3bc9A: 24.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ESW_A_ACRA651_1 (AMYLOMALTASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	5 / 12	TYR A 184 HIS A 354 HIS A 446 ASP A 447 TRP A 131	ACI A 806 ( 4.0A) GLD A 807 ( 3.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A) None	1.30A	1eswA-3bc9A: 14.8	1eswA-3bc9A: 22.87
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KXH_A_ACRA598_1 (ALPHA-AMYLASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	5 / 12	TRP A 131 GLY A 317 ALA A 351 GLU A 380 ASP A 447	None ACI A 803 (-3.3A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-2.9A)	0.86A	1kxhA-3bc9A: 27.5	1kxhA-3bc9A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1KXH_A_ACRA598_1 (ALPHA-AMYLASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	5 / 12	TRP A 131 HIS A 233 ALA A 351 GLU A 380 ASP A 447	None ACI A 806 (-4.4A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-2.9A)	0.81A	1kxhA-3bc9A: 27.5	1kxhA-3bc9A: 21.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA735_1 (ALPHA AMYLASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	10 / 12	TRP A 131 TYR A 184 HIS A 233 ARG A 348 ASP A 350 LYS A 353 GLU A 380 TRP A 382 HIS A 446 ASP A 447	None ACI A 806 ( 4.0A) ACI A 806 (-4.4A) ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLC A 808 (-2.9A) GLD A 807 ( 2.8A) GLC A 808 (-3.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.43A	1mxdA-3bc9A: 39.8	1mxdA-3bc9A: 28.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_A_ACRA5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	ARG A 348 ASP A 350 GLU A 380 ARG A 409 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A)	1.11A	3aicA-3bc9A: 13.6	3aicA-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_A_ACRA5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	LEU A 315 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	None ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.63A	3aicA-3bc9A: 13.6	3aicA-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_B_ACRB5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	ARG A 348 ASP A 350 GLU A 380 ARG A 409 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A)	1.16A	3aicB-3bc9A: 13.6	3aicB-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_B_ACRB5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	LEU A 315 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	None ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.61A	3aicB-3bc9A: 13.6	3aicB-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_C_ACRC5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447 TYR A 184	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A) ACI A 806 ( 4.0A)	0.56A	3aicC-3bc9A: 13.7	3aicC-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_C_ACRC5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	ARG A 348 ASP A 350 GLU A 380 ARG A 409 HIS A 446 ASP A 447 TYR A 184	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A) ACI A 806 ( 4.0A)	1.10A	3aicC-3bc9A: 13.7	3aicC-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_D_ACRD5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	ARG A 348 ASP A 350 GLU A 380 ARG A 409 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A)	1.19A	3aicD-3bc9A: 13.8	3aicD-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_D_ACRD5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	LEU A 315 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	None ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.65A	3aicD-3bc9A: 13.8	3aicD-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_E_ACRE5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	ARG A 348 ASP A 350 GLU A 380 ARG A 409 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A)	1.14A	3aicE-3bc9A: 13.8	3aicE-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_E_ACRE5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	LEU A 315 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	None ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.64A	3aicE-3bc9A: 13.8	3aicE-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_F_ACRF5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	ARG A 348 ASP A 350 GLU A 380 ARG A 409 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A)	1.15A	3aicF-3bc9A: 13.7	3aicF-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_F_ACRF5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	LEU A 315 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	None ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.62A	3aicF-3bc9A: 13.7	3aicF-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_G_ACRG5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	6 / 12	ARG A 348 ASP A 350 GLU A 380 ARG A 409 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A)	1.15A	3aicG-3bc9A: 13.8	3aicG-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_G_ACRG5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	LEU A 315 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	None ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.60A	3aicG-3bc9A: 13.8	3aicG-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_H_ACRH5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	ARG A 348 ASP A 350 ALA A 351 GLU A 380 ARG A 409 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) None ACI A 806 (-4.1A) ACI A 806 (-2.9A)	1.13A	3aicH-3bc9A: 13.7	3aicH-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3AIC_H_ACRH5044_1 (GLUCOSYLTRANSFERASE- SI)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	7 / 12	LEU A 315 ARG A 348 ASP A 350 ALA A 351 GLU A 380 HIS A 446 ASP A 447	None ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 (-3.6A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.68A	3aicH-3bc9A: 13.7	3aicH-3bc9A: 22.03
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4DR2_A_PARA1609_1 (16S RRNA 30S RIBOSOMAL PROTEIN S9 30S RIBOSOMAL PROTEIN S10)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	3 / 3	TYR A 455 ARG A 450 SER A 454	GLD A 807 (-3.7A) GLC A 805 (-3.1A) None	0.95A	4dr2I-3bc9A: undetectable 4dr2J-3bc9A: undetectable	4dr2I-3bc9A: 12.79 4dr2J-3bc9A: 9.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4MI4_C_SPMC201_1 (SPERMIDINE N1-ACETYLTRANSFERASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	4 / 7	TYR A 455 ASN A 232 TYR A 184 GLU A 380	GLD A 807 (-3.7A) CA A 702 (-3.1A) ACI A 806 ( 4.0A) GLD A 807 ( 2.8A)	1.05A	4mi4A-3bc9A: undetectable 4mi4C-3bc9A: undetectable	4mi4A-3bc9A: 15.99 4mi4C-3bc9A: 15.99
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5CSY_B_ACRB601_1 (4-ALPHA-GLUCANOTRANS FERASE DPE1, CHLOROPLASTIC/AMYLOP LASTIC)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	5 / 12	ARG A 348 ASP A 350 GLU A 380 HIS A 446 ASP A 447	ACI A 806 (-3.3A) ACI A 806 (-3.1A) GLD A 807 ( 2.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.35A	5csyB-3bc9A: 5.8	5csyB-3bc9A: 21.48
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA610_0 (ALPHA-AMYLASE)	1ua7	ALPHA-AMYLASE (Bacillus subtilis)	6 / 12	TRP A 58 TYR A 62 LEU A 144 ASP A 176 HIS A 268 ASP A 269	None ACI A 504 ( 3.7A) GLD A 502 ( 4.8A) ACI A 504 (-3.0A) ACI A 504 (-3.8A) ACI A 504 ( 2.8A)	1.39A	6ag0A-1ua7A: 28.6	6ag0A-1ua7A: 11.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_A_ACRA610_0 (ALPHA-AMYLASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	10 / 12	TRP A 131 TYR A 184 HIS A 233 LEU A 315 MET A 316 ASP A 350 LYS A 353 HIS A 354 HIS A 446 ASP A 447	None ACI A 806 ( 4.0A) ACI A 806 (-4.4A) None GLC A 805 (-3.7A) ACI A 806 (-3.1A) GLC A 808 (-2.9A) GLD A 807 ( 3.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.43A	6ag0A-3bc9A: 48.4	6ag0A-3bc9A: 15.02
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6AG0_C_ACRC608_0 (ALPHA-AMYLASE)	3bc9	ALPHA AMYLASE, CATALYTIC REGION (Halothermothrix orenii)	8 / 12	TRP A 131 LEU A 315 MET A 316 ASP A 350 LYS A 353 HIS A 354 HIS A 446 ASP A 447	None None GLC A 805 (-3.7A) ACI A 806 (-3.1A) GLC A 808 (-2.9A) GLD A 807 ( 3.8A) ACI A 806 (-4.1A) ACI A 806 (-2.9A)	0.45A	6ag0C-3bc9A: 48.4	6ag0C-3bc9A: 15.02

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","1ua7","ALPHA-AMYLASE","Bacillus subtilis",6,"TYR A  62;LEU A 141;LEU A 142;ASP A 176;ALA A 177;HIS A 268","ACI A 504 ( 3.7A);G6D A 505 ( 4.7A);GLD A 502 (-4.1A);ACI A 504 (-3.0A);G6D A 505 (-3.4A);ACI A 504 (-3.8A)","1.47A","1dedA-1ua7A:30.9",null],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","1ua7","ALPHA-AMYLASE","Bacillus subtilis",7,"TYR A  62;LEU A 141;LEU A 144;ASP A 176;ALA A 177;HIS A 268;ASP A 269","ACI A 504 ( 3.7A);G6D A 505 ( 4.7A);GLD A 502 ( 4.8A);ACI A 504 (-3.0A);G6D A 505 (-3.4A);ACI A 504 (-3.8A);ACI A 504 ( 2.8A)","0.59A","1dedA-1ua7A:30.9","1dedA-1ua7A:23.15"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"LEU A 315;ASP A 350;ALA A 351;HIS A 446;ASP A 447;ARG A 450","None;ACI A 806 (-3.1A);GLD A 807 (-3.6A);ACI A 806 (-4.1A);ACI A 806 (-2.9A);GLC A 805 (-3.1A)","1.10A","1dedA-3bc9A:27.1","1dedA-1ua7A:23.15"],["1DED_A_QPSA1001_1","CYCLODEXTRIN GLUCANOTRANSFERASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"TYR A 184;LEU A 315;ASP A 350;ALA A 351;HIS A 446;ASP A 447","ACI A 806 ( 4.0A);None;ACI A 806 (-3.1A);GLD A 807 (-3.6A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.70A","1dedA-3bc9A:27.1","1dedA-3bc9A:24.12"],["1DED_B_QPSB1501_1","CYCLODEXTRIN GLUCANOTRANSFERASE","1ua7","ALPHA-AMYLASE","Bacillus subtilis",7,"TYR A  62;LEU A 142;ARG A 174;ASP A 176;ALA A 177;GLU A 208;HIS A 268","ACI A 504 ( 3.7A);GLD A 502 (-4.1A);ACI A 504 (-3.5A);ACI A 504 (-3.0A);G6D A 505 (-3.4A);ACI A 504 ( 2.9A);ACI A 504 (-3.8A)","1.27A","1dedB-1ua7A:28.5","1dedA-3bc9A:24.12"],["1DED_B_QPSB1501_1","CYCLODEXTRIN GLUCANOTRANSFERASE","1ua7","ALPHA-AMYLASE","Bacillus subtilis",8,"TYR A  62;LEU A 144;ARG A 174;ASP A 176;ALA A 177;GLU A 208;HIS A 268;ASP A 269","ACI A 504 ( 3.7A);GLD A 502 ( 4.8A);ACI A 504 (-3.5A);ACI A 504 (-3.0A);G6D A 505 (-3.4A);ACI A 504 ( 2.9A);ACI A 504 (-3.8A);ACI A 504 ( 2.8A)","0.64A","1dedB-1ua7A:28.5","1dedB-1ua7A:23.15"],["1DED_B_QPSB1501_1","CYCLODEXTRIN GLUCANOTRANSFERASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"TYR A 184;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ARG A 450","ACI A 806 ( 4.0A);ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);GLC A 805 (-3.1A)","1.03A","1dedB-3bc9A:24.4","1dedB-1ua7A:23.15"],["1DED_B_QPSB1501_1","CYCLODEXTRIN GLUCANOTRANSFERASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"TYR A 184;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","ACI A 806 ( 4.0A);ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.71A","1dedB-3bc9A:24.4","1dedB-3bc9A:24.12"],["1ESW_A_ACRA651_1","AMYLOMALTASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",5,"TYR A 184;HIS A 354;HIS A 446;ASP A 447;TRP A 131","ACI A 806 ( 4.0A);GLD A 807 ( 3.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A);None","1.30A","1eswA-3bc9A:14.8","1dedB-3bc9A:24.12"],["1KXH_A_ACRA598_1","ALPHA-AMYLASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",5,"TRP A 131;GLY A 317;ALA A 351;GLU A 380;ASP A 447","None;ACI A 803 (-3.3A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-2.9A)","0.86A","1kxhA-3bc9A:27.5","1eswA-3bc9A:22.87"],["1KXH_A_ACRA598_1","ALPHA-AMYLASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",5,"TRP A 131;HIS A 233;ALA A 351;GLU A 380;ASP A 447","None;ACI A 806 (-4.4A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-2.9A)","0.81A","1kxhA-3bc9A:27.5","1kxhA-3bc9A:21.85"],["1MXD_A_ACRA735_1","ALPHA AMYLASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",10,"TRP A 131;TYR A 184;HIS A 233;ARG A 348;ASP A 350;LYS A 353;GLU A 380;TRP A 382;HIS A 446;ASP A 447","None;ACI A 806 ( 4.0A);ACI A 806 (-4.4A);ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLC A 808 (-2.9A);GLD A 807 ( 2.8A);GLC A 808 (-3.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.43A","1mxdA-3bc9A:39.8","1kxhA-3bc9A:21.85"],["3AIC_A_ACRA5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"ARG A 348;ASP A 350;GLU A 380;ARG A 409;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A)","1.11A","3aicA-3bc9A:13.6","1mxdA-3bc9A:28.50"],["3AIC_A_ACRA5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"LEU A 315;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","None;ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.63A","3aicA-3bc9A:13.6","3aicA-3bc9A:22.03"],["3AIC_B_ACRB5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"ARG A 348;ASP A 350;GLU A 380;ARG A 409;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A)","1.16A","3aicB-3bc9A:13.6","3aicA-3bc9A:22.03"],["3AIC_B_ACRB5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"LEU A 315;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","None;ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.61A","3aicB-3bc9A:13.6","3aicB-3bc9A:22.03"],["3AIC_C_ACRC5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447;TYR A 184","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A);ACI A 806 ( 4.0A)","0.56A","3aicC-3bc9A:13.7","3aicB-3bc9A:22.03"],["3AIC_C_ACRC5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"ARG A 348;ASP A 350;GLU A 380;ARG A 409;HIS A 446;ASP A 447;TYR A 184","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A);ACI A 806 ( 4.0A)","1.10A","3aicC-3bc9A:13.7","3aicC-3bc9A:22.03"],["3AIC_D_ACRD5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"ARG A 348;ASP A 350;GLU A 380;ARG A 409;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A)","1.19A","3aicD-3bc9A:13.8","3aicC-3bc9A:22.03"],["3AIC_D_ACRD5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"LEU A 315;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","None;ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.65A","3aicD-3bc9A:13.8","3aicD-3bc9A:22.03"],["3AIC_E_ACRE5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"ARG A 348;ASP A 350;GLU A 380;ARG A 409;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A)","1.14A","3aicE-3bc9A:13.8","3aicD-3bc9A:22.03"],["3AIC_E_ACRE5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"LEU A 315;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","None;ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.64A","3aicE-3bc9A:13.8","3aicE-3bc9A:22.03"],["3AIC_F_ACRF5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"ARG A 348;ASP A 350;GLU A 380;ARG A 409;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A)","1.15A","3aicF-3bc9A:13.7","3aicE-3bc9A:22.03"],["3AIC_F_ACRF5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"LEU A 315;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","None;ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.62A","3aicF-3bc9A:13.7","3aicF-3bc9A:22.03"],["3AIC_G_ACRG5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",6,"ARG A 348;ASP A 350;GLU A 380;ARG A 409;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A)","1.15A","3aicG-3bc9A:13.8","3aicF-3bc9A:22.03"],["3AIC_G_ACRG5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"LEU A 315;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","None;ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.60A","3aicG-3bc9A:13.8","3aicG-3bc9A:22.03"],["3AIC_H_ACRH5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"ARG A 348;ASP A 350;ALA A 351;GLU A 380;ARG A 409;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);None;ACI A 806 (-4.1A);ACI A 806 (-2.9A)","1.13A","3aicH-3bc9A:13.7","3aicG-3bc9A:22.03"],["3AIC_H_ACRH5044_1","GLUCOSYLTRANSFERASE-SI","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",7,"LEU A 315;ARG A 348;ASP A 350;ALA A 351;GLU A 380;HIS A 446;ASP A 447","None;ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 (-3.6A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.68A","3aicH-3bc9A:13.7","3aicH-3bc9A:22.03"],["4DR2_A_PARA1609_1","16S RRNA;30S RIBOSOMAL PROTEIN S9;30S RIBOSOMAL PROTEIN S10","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",3,"TYR A 455;ARG A 450;SER A 454","GLD A 807 (-3.7A);GLC A 805 (-3.1A);None","0.95A","4dr2I-3bc9A:undetectable;4dr2J-3bc9A:undetectable","3aicH-3bc9A:22.03"],["4MI4_C_SPMC201_1","SPERMIDINE N1-ACETYLTRANSFERASE;SPERMIDINE N1-ACETYLTRANSFERASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",4,"TYR A 455;ASN A 232;TYR A 184;GLU A 380","GLD A 807 (-3.7A); CA A 702 (-3.1A);ACI A 806 ( 4.0A);GLD A 807 ( 2.8A)","1.05A","4mi4A-3bc9A:undetectable;4mi4C-3bc9A:undetectable","4dr2I-3bc9A:12.79;4dr2J-3bc9A:9.11"],["5CSY_B_ACRB601_1","4-ALPHA-GLUCANOTRANSFERASE DPE1, CHLOROPLASTIC\/AMYLOPLASTIC","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",5,"ARG A 348;ASP A 350;GLU A 380;HIS A 446;ASP A 447","ACI A 806 (-3.3A);ACI A 806 (-3.1A);GLD A 807 ( 2.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.35A","5csyB-3bc9A:5.8","4mi4A-3bc9A:15.99;4mi4C-3bc9A:15.99"],["6AG0_A_ACRA610_0","ALPHA-AMYLASE","1ua7","ALPHA-AMYLASE","Bacillus subtilis",6,"TRP A  58;TYR A  62;LEU A 144;ASP A 176;HIS A 268;ASP A 269","None;ACI A 504 ( 3.7A);GLD A 502 ( 4.8A);ACI A 504 (-3.0A);ACI A 504 (-3.8A);ACI A 504 ( 2.8A)","1.39A","6ag0A-1ua7A:28.6","5csyB-3bc9A:21.48"],["6AG0_A_ACRA610_0","ALPHA-AMYLASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",10,"TRP A 131;TYR A 184;HIS A 233;LEU A 315;MET A 316;ASP A 350;LYS A 353;HIS A 354;HIS A 446;ASP A 447","None;ACI A 806 ( 4.0A);ACI A 806 (-4.4A);None;GLC A 805 (-3.7A);ACI A 806 (-3.1A);GLC A 808 (-2.9A);GLD A 807 ( 3.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.43A","6ag0A-3bc9A:48.4","6ag0A-1ua7A:11.81"],["6AG0_C_ACRC608_0","ALPHA-AMYLASE","3bc9","ALPHA AMYLASE, CATALYTIC REGION","Halothermothrix orenii",8,"TRP A 131;LEU A 315;MET A 316;ASP A 350;LYS A 353;HIS A 354;HIS A 446;ASP A 447","None;None;GLC A 805 (-3.7A);ACI A 806 (-3.1A);GLC A 808 (-2.9A);GLD A 807 ( 3.8A);ACI A 806 (-4.1A);ACI A 806 (-2.9A)","0.45A","6ag0C-3bc9A:48.4","6ag0A-3bc9A:15.02"]]