SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GIV'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DDW_B_PXLB1005_1
(PYRIDOXINE KINASE)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 7 LEU A 642
PRO A 665
HIS A 664
GLY A 671
 None
None
GIV  A1809 (-4.0A)
None
 1.04A 2ddwB-4ufcA:
undetectable		 2ddwB-4ufcA:
17.88
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O1E_B_C2FB4000_0
(DIHYDROPTEROATE
SYNTHASE DHPS)		 4ufc GH95
(Bacteroides
ovatus) 		5 / 12 GLU A 376
ASN A 378
ASP A 670
ASN A 423
ILE A 373
 None
None
None
GIV  A1809 ( 4.6A)
None
 1.13A 4o1eB-4ufcA:
undetectable		 4o1eB-4ufcA:
16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B2Q_A_ACTA1729_0
(CRISPR-ASSOCIATED
ENDONUCLEASE CAS9)		 4ufc GH95
(Bacteroides
ovatus) 		4 / 5 GLN A 668
THR A 375
ASP A 670
ASN A 378
 GIV  A1809 ( 4.8A)
None
None
None
 1.38A 5b2qA-4ufcA:
0.0		 5b2qA-4ufcA:
19.58