SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GIF'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RU9_H_ACTH611_0 (IMMUNOGLOBULINIGG2A, HEAVY CHAINIMMUNOGLOBULINIGG2A, LIGHT CHAIN) |
5t9g | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) | 4 / 6 | TRP A 657ASN A 553LEU A 554PHE A 460 | GIF A 901 ( 4.4A)NoneNoneNone | 1.06A | 1ru9H-5t9gA:5.81ru9L-5t9gA:5.1 | 1ru9H-5t9gA:12.131ru9L-5t9gA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 1RUK_L_ACTL611_0 (IMMUNOGLOBULINIGG2A, HEAVY CHAINIMMUNOGLOBULINIGG2A, LIGHT CHAIN) |
5t9g | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) | 4 / 6 | TRP A 657ASN A 553LEU A 554PHE A 460 | GIF A 901 ( 4.4A)NoneNoneNone | 1.08A | 1rukH-5t9gA:5.91rukL-5t9gA:6.3 | 1rukH-5t9gA:12.131rukL-5t9gA:14.43 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2F0Z_A_ZMRA381_1 (SIALIDASE 2) |
5t9g | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) | 5 / 12 | GLU A 583ASN A 390TYR A 459GLU A 436ARG A 352 | GIF A 901 (-2.9A)GIF A 901 (-3.7A)NoneGIF A 901 (-2.9A)None | 1.39A | 2f0zA-5t9gA:undetectable | 2f0zA-5t9gA:17.21 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2V3D_B_NBVB1504_1 (GLUCOSYLCERAMIDASE) |
5t9g | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) | 5 / 11 | ASN A 435GLU A 436TYR A 531GLU A 552TRP A 575 | GIF A 901 ( 4.0A)GIF A 901 (-2.9A)NoneGIF A 901 (-2.8A)GIF A 901 (-4.0A) | 0.69A | 2v3dB-5t9gA:14.4 | 2v3dB-5t9gA:19.33 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3OWX_B_XRAB233_1 (RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE[QUINONE]) |
5t9g | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) | 5 / 11 | PHE A 460TRP A 657GLY A 550ASN A 508ILE A 569 | NoneGIF A 901 ( 4.4A)NoneNoneNone | 1.28A | 3owxA-5t9gA:undetectable3owxB-5t9gA:undetectable | 3owxA-5t9gA:13.923owxB-5t9gA:13.92 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3R94_A_FLRA332_1 (ALDO-KETO REDUCTASEFAMILY 1 MEMBER C3) |
5t9g | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) | 5 / 12 | LEU A 554SER A 530TYR A 536TRP A 461PRO A 512 | NoneGIF A 901 ( 4.7A)NoneNoneNone | 1.48A | 3r94A-5t9gA:9.5 | 3r94A-5t9gA:16.47 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4ZVM_B_DM2B303_1 (RIBOSYLDIHYDRONICOTINAMIDE DEHYDROGENASE[QUINONE]) |
5t9g | GLYCOSIDE HYDROLASE (Bacteroidesuniformis) | 5 / 11 | PHE A 460TRP A 657GLY A 550ASN A 508ILE A 569 | NoneGIF A 901 ( 4.4A)NoneNoneNone | 1.33A | 4zvmA-5t9gA:undetectable4zvmB-5t9gA:undetectable | 4zvmA-5t9gA:13.924zvmB-5t9gA:13.92 |