SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GGB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1A4L_B_DCFB853_2
(ADENOSINE DEAMINASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 5 LEU A 259
SER A 214
LEU A 218
GLY A 229
 None
None
None
GGB  A 403 (-3.3A)
 1.07A 1a4lB-5utiA:
5.3		 1a4lB-5utiA:
12.77
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LHU_A_ESTA301_1
(SEX HORMONE-BINDING
GLOBULIN)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 12 GLY A 200
MET A 278
LEU A 100
MET A 153
ILE A 201
 None
None
None
None
GGB  A 403 ( 4.9A)
 0.98A 1lhuA-5utiA:
undetectable		 1lhuA-5utiA:
24.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1X8V_A_ESLA472_1
(CYTOCHROME P450 51)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 6 MET A 260
MET A 240
VAL A 243
LEU A 244
 GGB  A 403 (-3.7A)
None
None
None
 0.77A 1x8vA-5utiA:
undetectable		 1x8vA-5utiA:
11.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5KVA_B_SAMB301_1
(CAFFEOYL-COA
O-METHYLTRANSFERASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		3 / 3 THR A  71
SER A 140
ASP A 156
 None
None
GGB  A 403 (-3.1A)
 0.76A 5kvaB-5utiA:
2.7		 5kvaB-5utiA:
undetectable
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 9 ASP A 156
GLN A 203
GLY A 229
ALA A 232
MET A 260
 GGB  A 403 (-3.1A)
None
GGB  A 403 (-3.3A)
GGB  A 403 ( 4.1A)
GGB  A 403 (-3.7A)
 1.33A 5v3cA-5utiA:
58.7		 5v3cA-5utiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		8 / 9 TYR A 106
ASP A 156
GLN A 203
GLY A 229
GLY A 230
ALA A 232
VAL A 233
MET A 260
 GGB  A 403 (-3.9A)
GGB  A 403 (-3.1A)
None
GGB  A 403 (-3.3A)
GGB  A 403 (-3.8A)
GGB  A 403 ( 4.1A)
None
GGB  A 403 (-3.7A)
 0.36A 5v3cA-5utiA:
58.7		 5v3cA-5utiA:
100.00
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
5V3C_A_AMHA402_1
(QUEUINE
TRNA-RIBOSYLTRANSFER
ASE)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		5 / 9 TYR A 106
CYH A 158
GLN A 203
GLY A 229
MET A 260
 GGB  A 403 (-3.9A)
GGB  A 403 (-3.6A)
None
GGB  A 403 (-3.3A)
GGB  A 403 (-3.7A)
 1.26A 5v3cA-5utiA:
58.7		 5v3cA-5utiA:
100.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JI6_A_ACTA305_0
(GLUTATHIONE
S-TRANSFERASE
CLASS-MU 26 KDA
ISOZYME)		 5uti QUEUINE
TRNA-RIBOSYLTRANSFER
ASE
(Zymomonas
mobilis) 		4 / 5 GLY A 229
LEU A 231
SER A 247
GLN A 202
 GGB  A 403 (-3.3A)
None
None
None
 1.27A 6ji6A-5utiA:
undetectable		 6ji6A-5utiA:
undetectable