SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GDN'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
11GS_B_EAAB211_1
(GLUTATHIONE
S-TRANSFERASE)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 7 TYR A   7
PHE A   8
GLY A  12
ARG A  13
 None
GDN  A 203 (-4.5A)
None
GDN  A 203 (-4.9A)
 0.46A 11gsB-1gsqA:
25.7		 11gsB-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1HA2_A_SWFA3001_1
(SERUM ALBUMIN)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 11 ALA A  22
LEU A  21
SER A  63
ILE A  66
ALA A  67
 None
None
GDN  A 203 (-2.6A)
None
None
 0.93A 1ha2A-1gsqA:
undetectable		 1ha2A-1gsqA:
16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1LIN_A_TFPA155_1
(CALMODULIN)		 6f4f GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 7 GLU A 116
MET A  84
PHE A  14
ALA A 163
 None
None
GDN  A 301 ( 4.9A)
None
 1.23A 1linA-6f4fA:
undetectable		 1linA-6f4fA:
18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ONI_B_BEZB503_0
(14.5 KDA
TRANSLATIONAL
INHIBITOR PROTEIN)		 1hna GLUTATHIONE
S-TRANSFERASE
(Homo
sapiens) 		4 / 6 ARG A  17
ALA A  13
ILE A  75
PRO A  60
 None
None
None
GDN  A 218 ( 4.6A)
 1.27A 1oniB-1hnaA:
undetectable
1oniC-1hnaA:
undetectable		 1oniB-1hnaA:
23.33
1oniC-1hnaA:
23.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_A_EAAA0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
ARG A  13
TRP A  38
 None
GDN  A 203 (-4.5A)
GDN  A 203 (-4.9A)
GDN  A 203 (-4.1A)
 0.60A 2gssA-1gsqA:
25.7		 2gssA-1gsqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
2GSS_B_EAAB0_1
(GLUTATHIONE
S-TRANSFERASE P1-1)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
ARG A  13
TRP A  38
 None
GDN  A 203 (-4.5A)
GDN  A 203 (-4.9A)
GDN  A 203 (-4.1A)
 0.60A 2gssB-1gsqA:
25.7		 2gssB-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2OTH_A_NIMA300_1
(PHOSPHOLIPASE A2
VRV-PL-VIIIA)		 6f4f GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 5 LEU A  40
ALA A  12
ILE A  56
SER A  15
 GDN  A 301 (-3.8A)
None
GDN  A 301 (-4.3A)
GDN  A 301 ( 3.7A)
 1.01A 2othA-6f4fA:
undetectable		 2othA-6f4fA:
18.18
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3CSJ_B_CBLB211_0
(GLUTATHIONE
S-TRANSFERASE P)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		5 / 9 TYR A   7
PHE A   8
PRO A   9
GLY A  12
ARG A  13
 None
GDN  A 203 (-4.5A)
None
None
GDN  A 203 (-4.9A)
 0.64A 3csjB-1gsqA:
25.8		 3csjB-1gsqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_A_EAAA210_1
(GLUTATHIONE
S-TRANSFERASE P)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
ARG A  13
TRP A  38
 None
GDN  A 203 (-4.5A)
GDN  A 203 (-4.9A)
GDN  A 203 (-4.1A)
 0.64A 3n9jA-1gsqA:
25.7		 3n9jA-1gsqA:
32.43
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.
3N9J_B_EAAB214_1
(GLUTATHIONE
S-TRANSFERASE P)		 1gsq GLUTATHIONE
S-TRANSFERASE
(Todarodes
pacificus) 		4 / 8 TYR A   7
PHE A   8
GLY A  12
ARG A  13
 None
GDN  A 203 (-4.5A)
None
GDN  A 203 (-4.9A)
 0.50A 3n9jB-1gsqA:
25.6		 3n9jB-1gsqA:
32.43
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VLN_A_ASCA904_0
(GLUTATHIONE
S-TRANSFERASE
OMEGA-1)		 6f4f GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		4 / 6 ARG A  20
PRO A  57
GLU A  80
SER A  81
 None
GDN  A 301 (-4.3A)
GDN  A 301 (-2.7A)
GDN  A 301 (-2.6A)
 0.41A 3vlnA-6f4fA:
21.8		 3vlnA-6f4fA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_0
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 6f4f GLUTATHIONE
TRANSFERASE
(Trametes
versicolor) 		5 / 12 ILE A 166
TYR A 206
PHE A 111
ALA A 154
SER A  81
 None
None
None
None
GDN  A 301 (-2.6A)
 1.44A 5iwuA-6f4fA:
undetectable		 5iwuA-6f4fA:
undetectable