SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GCP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1F5L_A_AMRA301_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR)		 3w6o DYNAMIN-1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 8 SER A  36
SER A  39
GLY A 149
GLY A  32
 GCP  A 801 (-4.0A)
MG  A 802 ( 2.0A)
GCP  A 801 (-3.6A)
None
 0.74A 1f5lA-3w6oA:
undetectable		 1f5lA-3w6oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1JFF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.12A 1jffB-5l3rB:
undetectable		 1jffB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2AVV_A_MK1A901_2
(POL POLYPROTEIN)		 1cee GTP-BINDING RHO-LIKE
PROTEIN
(Homo
sapiens) 		3 / 3 ASP A 118
VAL A  84
PRO A 139
 GCP  A 181 (-2.5A)
None
None
 0.57A 2avvA-1ceeA:
0.0		 2avvA-1ceeA:
19.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B25_A_SAMA601_0
(HYPOTHETICAL PROTEIN)		 4cz2 RAS-RELATED PROTEIN
RAB-32
(Homo
sapiens) 		5 / 12 THR A  57
GLY A  37
GLY A  35
GLY A  84
ASP A 146
 MG  A1199 ( 2.9A)
GCP  A1198 (-3.3A)
GCP  A1198 (-3.2A)
GCP  A1198 (-4.0A)
GCP  A1198 (-2.7A)
 0.98A 2b25A-4cz2A:
undetectable		 2b25A-4cz2A:
21.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 4cz2 RAS-RELATED PROTEIN
RAB-32
(Homo
sapiens) 		5 / 12 GLY A  84
LEU A 124
ASP A 123
ARG A  87
PHE A 167
 GCP  A1198 (-4.0A)
None
None
None
None
 1.35A 2b9eA-4cz2A:
undetectable		 2b9eA-4cz2A:
22.42
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXF_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.12A 2hxfB-5l3rB:
undetectable		 2hxfB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2HXH_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.12A 2hxhB-5l3rB:
undetectable		 2hxhB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNH_B_9CRB502_1
(CYTOCHROME P450 2C8)		 3gei TRNA MODIFICATION
GTPASE MNME
(Chlorobaculum
tepidum) 		5 / 10 ILE A 363
ILE A 331
LEU A 317
ASN A 348
ILE A 374
 None
None
None
GCP  A 474 (-3.5A)
None
 1.24A 2nnhB-3geiA:
undetectable		 2nnhB-3geiA:
23.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2P4N_B_TA1B601_1
(TUBULIN BETA CHAIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.12A 2p4nB-5l3rB:
undetectable		 2p4nB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VIN_A_505A1247_1
(UROKINASE-TYPE
PLASMINOGEN
ACTIVATOR CHAIN B)		 3w6o DYNAMIN-1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 8 SER A  36
SER A  39
GLY A 149
GLY A  32
 GCP  A 801 (-4.0A)
MG  A 802 ( 2.0A)
GCP  A 801 (-3.6A)
None
 0.79A 2vinA-3w6oA:
undetectable		 2vinA-3w6oA:
21.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2WBE_B_TA1B1439_1
(TUBULIN BETA-2B
CHAIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.12A 2wbeB-5l3rB:
undetectable		 2wbeB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y05_A_RALA802_1
(PROSTAGLANDIN
REDUCTASE 1)		 3w6o DYNAMIN-1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 7 TYR A 273
ASN A 280
GLY A 281
VAL A 245
 None
None
None
GCP  A 801 (-4.0A)
 0.93A 2y05A-3w6oA:
undetectable
2y05B-3w6oA:
undetectable		 2y05A-3w6oA:
22.82
2y05B-3w6oA:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens;
Homo
sapiens) 		3 / 3 THR A 225
SER B  80
LYS B  83
 None
GCP  B 701 (-4.5A)
GCP  B 701 (-2.5A)
 1.20A 3aocC-4p4sA:
undetectable		 3aocC-4p4sA:
13.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3AOC_C_ERYC3402_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens;
Homo
sapiens) 		3 / 3 THR B 225
SER A  80
LYS A  83
 None
GCP  A 401 (-4.4A)
GCP  A 401 (-2.6A)
 1.16A 3aocC-4p4sB:
3.0		 3aocC-4p4sB:
16.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3DCO_B_TA1B601_1
(BOVINE BETA TUBULIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.12A 3dcoB-5l3rB:
undetectable		 3dcoB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3EDL_B_TA1B601_1
(BETA TUBULIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.12A 3edlB-5l3rB:
undetectable		 3edlB-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3G4L_D_ROFD904_0
(CAMP-SPECIFIC
3',5'-CYCLIC
PHOSPHODIESTERASE 4D)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		5 / 12 LEU B 179
THR B 183
ILE B 182
SER B  80
GLN B  79
 None
None
None
GCP  B 701 (-4.5A)
GCP  B 701 (-3.8A)
 1.42A 3g4lD-4p4sB:
undetectable		 3g4lD-4p4sB:
22.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IZ0_B_TA1B820_1
(BETA TUBULIN, CHAIN
B FROM PDB 1JFF)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.09A 3iz0B-5l3rB:
undetectable		 3iz0B-5l3rB:
20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP A 262
GLU A 315
SER B  99
 None
None
GCP  B 701 ( 4.2A)
 0.70A 3p2kA-4p4sA:
undetectable		 3p2kA-4p4sA:
20.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3P2K_A_SAMA6735_1
(16S RRNA METHYLASE)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens;
Homo
sapiens) 		3 / 3 ASP B 262
GLU B 315
SER A  99
 None
None
GCP  A 401 ( 4.4A)
 0.72A 3p2kA-4p4sB:
undetectable		 3p2kA-4p4sB:
22.53
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3RXF_A_4APA9_1
(CATIONIC TRYPSIN)		 3w6o DYNAMIN-1-LIKE
PROTEIN
(Homo
sapiens) 		4 / 6 SER A  36
SER A  39
GLY A 149
GLY A  32
 GCP  A 801 (-4.0A)
MG  A 802 ( 2.0A)
GCP  A 801 (-3.6A)
None
 0.73A 3rxfA-3w6oA:
undetectable		 3rxfA-3w6oA:
21.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		5 / 10 VAL A 216
ALA A 228
SER A  80
VAL A  75
THR A 226
 None
None
GCP  A 401 (-4.4A)
None
None
 1.30A 4eilB-4p4sA:
undetectable		 4eilB-4p4sA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EIL_B_FOLB703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		5 / 10 VAL B 216
ALA B 228
SER B  80
VAL B  75
THR B 226
 None
None
GCP  B 701 (-4.5A)
None
None
 1.31A 4eilB-4p4sB:
undetectable		 4eilB-4p4sB:
19.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FR0_A_SAMA401_0
(ARSENIC
METHYLTRANSFERASE)		 5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 GLY A 183
GLY A 268
ASP A 265
LEU A 270
VAL A 187
 None
GCP  A 401 (-3.4A)
MG  A 402 (-3.9A)
GCP  B 401 ( 4.9A)
GCP  A 401 (-4.2A)
 1.05A 4fr0A-5l3rA:
2.3		 4fr0A-5l3rA:
24.63
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_C_FOLC703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		5 / 10 VAL A 216
ALA A 228
SER A  80
VAL A  75
THR A 226
 None
None
GCP  A 401 (-4.4A)
None
None
 1.34A 4kyaC-4p4sA:
undetectable		 4kyaC-4p4sA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_E_FOLE703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		5 / 11 VAL A 216
ALA A 228
SER A  80
VAL A  75
THR A 226
 None
None
GCP  A 401 (-4.4A)
None
None
 1.35A 4kyaE-4p4sA:
undetectable		 4kyaE-4p4sA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KYA_G_FOLG703_0
(BIFUNCTIONAL
DIHYDROFOLATE
REDUCTASE-THYMIDYLAT
E SYNTHASE)		 4p4s INTERFERON-INDUCED
GTP-BINDING PROTEIN
MX1
(Homo
sapiens) 		5 / 11 VAL A 216
ALA A 228
SER A  80
VAL A  75
THR A 226
 None
None
GCP  A 401 (-4.4A)
None
None
 1.35A 4kyaG-4p4sA:
undetectable		 4kyaG-4p4sA:
16.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_A_PAUA301_0
(TYPE III
PANTOTHENATE KINASE)		 5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		5 / 12 ASN B 294
GLY B 346
ASP B 321
GLN A 185
THR B 179
 None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
 1.19A 4o5fA-5l3rB:
undetectable
4o5fB-5l3rB:
undetectable		 4o5fA-5l3rB:
22.15
4o5fB-5l3rB:
22.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4O5F_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		5 / 12 GLN A 185
THR B 179
ASN B 294
GLY B 346
ASP B 321
 GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
 1.18A 4o5fA-5l3rA:
undetectable
4o5fB-5l3rA:
undetectable		 4o5fA-5l3rA:
25.46
4o5fB-5l3rA:
25.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_A_AG2A505_1
(HOMOSPERMIDINE
SYNTHASE)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ALA A 219
PRO A 217
GLU B 347
ASP A 265
THR A 190
 MG  A 402 ( 3.7A)
None
GCP  B 401 (-3.5A)
MG  A 402 (-3.9A)
MG  A 402 ( 3.5A)
 1.45A 4xqeA-5l3rA:
2.7		 4xqeA-5l3rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XQE_B_AG2B504_1
(HOMOSPERMIDINE
SYNTHASE)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ALA A 219
PRO A 217
GLU B 347
ASP A 265
THR A 190
 MG  A 402 ( 3.7A)
None
GCP  B 401 (-3.5A)
MG  A 402 (-3.9A)
MG  A 402 ( 3.5A)
 1.44A 4xqeB-5l3rA:
2.8		 4xqeB-5l3rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4XRG_B_AG2B502_1
(HOMOSPERMIDINE
SYNTHASE)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ALA A 219
PRO A 217
GLU B 347
ASP A 265
THR A 190
 MG  A 402 ( 3.7A)
None
GCP  B 401 (-3.5A)
MG  A 402 (-3.9A)
MG  A 402 ( 3.5A)
 1.45A 4xrgB-5l3rA:
2.6		 4xrgB-5l3rA:
21.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4ZJL_A_ERYA1101_0
(MULTIDRUG EFFLUX
PUMP SUBUNIT ACRB)		 3w6o DYNAMIN-1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 SER A  40
GLU A  89
LEU A  67
GLY A  -1
MET A   1
 GCP  A 801 (-2.6A)
None
None
None
None
 1.44A 4zjlA-3w6oA:
undetectable		 4zjlA-3w6oA:
16.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_A_PAUA302_0
(TYPE III
PANTOTHENATE KINASE)		 5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		5 / 12 ASN B 294
GLY B 346
ASP B 321
GLN A 185
THR B 179
 None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
 1.12A 5b8hA-5l3rB:
2.1
5b8hB-5l3rB:
undetectable		 5b8hA-5l3rB:
23.17
5b8hB-5l3rB:
23.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B8H_B_PAUB302_0
(TYPE III
PANTOTHENATE KINASE)		 5l3r SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana;
Arabidopsis
thaliana) 		5 / 12 GLN A 185
THR B 179
ASN B 294
GLY B 346
ASP B 321
 GCP  B 401 ( 3.6A)
GCP  B 401 (-3.6A)
None
GCP  B 401 (-3.4A)
GCP  B 401 (-3.2A)
 1.19A 5b8hA-5l3rA:
undetectable
5b8hB-5l3rA:
undetectable		 5b8hA-5l3rA:
24.70
5b8hB-5l3rA:
24.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNW_B_TA1B902_1
(TUBULIN BETA-2B
CHAIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.07A 5hnwB-5l3rB:
undetectable		 5hnwB-5l3rB:
20.32
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5HNY_B_TA1B601_1
(TUBULIN BETA-2B
CHAIN)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ASP B 108
LEU A 325
SER A 120
LEU A 322
THR A 323
 None
None
None
None
GCP  A 401 ( 4.8A)
 1.08A 5hnyB-5l3rB:
undetectable		 5hnyB-5l3rB:
20.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGW_A_CTYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 3w6o DYNAMIN-1-LIKE
PROTEIN
(Homo
sapiens) 		5 / 12 ILE A 166
GLY A 149
SER A 175
ILE A 174
PHE A 173
 None
GCP  A 801 (-3.6A)
None
None
None
 1.04A 5igwA-3w6oA:
undetectable		 5igwA-3w6oA:
21.22
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5NFJ_C_SAMC501_0
(MITOCHONDRIAL
RIBONUCLEASE P
PROTEIN 1)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 ILE B 343
GLY B 344
THR B 179
SER B 180
LEU B 315
 None
GCP  B 401 (-3.5A)
GCP  B 401 (-3.6A)
GCP  B 401 ( 4.9A)
None
 1.21A 5nfjC-5l3rB:
undetectable		 5nfjC-5l3rB:
22.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5VLM_D_CVID301_1
(REGULATORY PROTEIN
TETR)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		4 / 8 GLY B 344
GLU B 347
GLN B 302
ASP B 292
 GCP  B 401 (-3.5A)
GCP  B 401 (-3.5A)
None
None
 1.05A 5vlmD-5l3rB:
3.0		 5vlmD-5l3rB:
21.78
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6BRD_C_RFPC502_1
(RIFAMPIN
MONOOXYGENASE)		 5l3r CELL DIVISION
PROTEIN FTSY
HOMOLOG,
CHLOROPLASTIC
SIGNAL RECOGNITION
PARTICLE 54 KDA
PROTEIN,
CHLOROPLASTIC
(Arabidopsis
thaliana) 		5 / 12 VAL B 332
VAL B 329
GLY B 175
THR A 300
GLY A 301
 None
None
GCP  B 401 (-4.1A)
None
None
 1.14A 6brdC-5l3rB:
undetectable		 6brdC-5l3rB:
13.59