SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GCH'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1ONI_B_BEZB504_0 (14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN)	1eio	ILEAL LIPID BINDING PROTEIN (Sus scrofa)	4 / 7	LEU A 108 ILE A 103 ALA A 101 ILE A 65	None None GCH A 128 ( 4.2A) None	0.95A	1oniB-1eioA: 0.0 1oniC-1eioA: 0.0	1oniB-1eioA: 18.06 1oniC-1eioA: 18.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3APW_B_DP0B190_1 (ALPHA-1-ACID GLYCOPROTEIN 2)	1eio	ILEAL LIPID BINDING PROTEIN (Sus scrofa)	5 / 12	ILE A 74 PHE A 17 ARG A 121 ALA A 101 TYR A 97	GCH A 128 ( 3.1A) None GCH A 128 ( 4.3A) GCH A 128 ( 4.2A) GCH A 128 (-3.1A)	1.15A	3apwB-1eioA: 3.1	3apwB-1eioA: 19.78
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3ELZ_A_CHDA150_0 (ILEAL BILE ACID-BINDING PROTEIN)	1eio	ILEAL LIPID BINDING PROTEIN (Sus scrofa)	5 / 12	TRP A 49 ASN A 61 PHE A 63 VAL A 83 TYR A 97	GCH A 128 ( 2.8A) GCH A 128 (-2.8A) GCH A 128 ( 4.2A) None GCH A 128 (-3.1A)	0.81A	3elzA-1eioA: 15.2	3elzA-1eioA: 49.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3GSS_A_EAAA212_1 (GLUTATHIONE S-TRANSFERASE P1-1)	1eio	ILEAL LIPID BINDING PROTEIN (Sus scrofa)	4 / 7	TYR A 119 PHE A 17 ILE A 59 THR A 73	None None GCH A 128 ( 3.7A) None	0.94A	3gssA-1eioA: undetectable	3gssA-1eioA: 21.03

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1ONI_B_BEZB504_0","14.5 KDA TRANSLATIONAL INHIBITOR PROTEIN","1eio","ILEAL LIPID BINDING PROTEIN","Sus scrofa",4,"LEU A 108;ILE A 103;ALA A 101;ILE A  65","None;None;GCH A 128 ( 4.2A);None","0.95A","1oniB-1eioA:0.0;1oniC-1eioA:0.0",null],["3APW_B_DP0B190_1","ALPHA-1-ACID GLYCOPROTEIN 2","1eio","ILEAL LIPID BINDING PROTEIN","Sus scrofa",5,"ILE A  74;PHE A  17;ARG A 121;ALA A 101;TYR A  97","GCH A 128 ( 3.1A);None;GCH A 128 ( 4.3A);GCH A 128 ( 4.2A);GCH A 128 (-3.1A)","1.15A","3apwB-1eioA:3.1","1oniB-1eioA:18.06;1oniC-1eioA:18.06"],["3ELZ_A_CHDA150_0","ILEAL BILE ACID-BINDING PROTEIN","1eio","ILEAL LIPID BINDING PROTEIN","Sus scrofa",5,"TRP A  49;ASN A  61;PHE A  63;VAL A  83;TYR A  97","GCH A 128 ( 2.8A);GCH A 128 (-2.8A);GCH A 128 ( 4.2A);None;GCH A 128 (-3.1A)","0.81A","3elzA-1eioA:15.2","3apwB-1eioA:19.78"],["3GSS_A_EAAA212_1","GLUTATHIONE S-TRANSFERASE P1-1","1eio","ILEAL LIPID BINDING PROTEIN","Sus scrofa",4,"TYR A 119;PHE A  17;ILE A  59;THR A  73","None;None;GCH A 128 ( 3.7A);None","0.94A","3gssA-1eioA:undetectable","3elzA-1eioA:49.24"]]