SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GB0'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4HYT_A_OBNA1104_2
(SODIUM/POTASSIUM-TRA
NSPORTING ATPASE
SUBUNIT ALPHA-1)		 5v8k P800 REACTION CENTER
CORE PROTEIN
(Heliobacterium
modesticaldum) 		4 / 5 ASP A 351
ASN A 347
ILE A 485
VAL A 388
 None
None
None
GB0  A1001 ( 4.7A)
 1.43A 4hytA-5v8kA:
undetectable		 4hytA-5v8kA:
21.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4KN2_C_LYAC304_2
(FOLATE RECEPTOR BETA)		 5v8k P800 REACTION CENTER
CORE PROTEIN
(Heliobacterium
modesticaldum) 		3 / 3 TYR A 510
GLN A 458
TRP A 464
 GB0  A1001 ( 2.7A)
GB0  A1001 (-3.7A)
None
 1.12A 4kn2C-5v8kA:
undetectable		 4kn2C-5v8kA:
13.14