SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GAX'

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)	View	Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1MXD_A_ACRA733_1 (ALPHA AMYLASE)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	4 / 6	SER A 174 THR A 173 ASN A 142 LEU A 168	GAX  A 352 (-2.8A) None None None	1.34A	1mxdA-2rhqA: undetectable	1mxdA-2rhqA: 20.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3KEE_B_30BB500_1 (GENOME POLYPROTEIN)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	5 / 12	GLN A 214 VAL A 292 GLY A 217 ARG A 179 ALA A 178	GAX  A 352 (-4.2A) GAX  A 352 ( 4.5A) None None GAX  A 352 ( 4.9A)	1.09A	3keeB-2rhqA: undetectable	3keeB-2rhqA: 18.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TEG_A_DAHA416_1 (PHENYLALANYL-TRNA SYNTHETASE, MITOCHONDRIAL)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	8 / 12	GLN A 214 PHE A 254 PHE A 256 THR A 257 GLY A 288 GLY A 290 ALA A 311 GLY A 313	GAX  A 352 (-4.2A) GAX  A 352 (-3.8A) GAX  A 352 (-4.6A) GAX  A 352 (-3.9A) GAX  A 352 (-3.2A) None GAX  A 352 (-3.4A) GAX  A 352 (-3.2A)	0.69A	3tegA-2rhqA: 24.6	3tegA-2rhqA: 24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TEG_A_DAHA416_1 (PHENYLALANYL-TRNA SYNTHETASE, MITOCHONDRIAL)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	8 / 12	GLU A 216 PHE A 254 PHE A 256 THR A 257 GLY A 288 GLY A 290 ALA A 311 GLY A 313	GAX  A 352 (-3.7A) GAX  A 352 (-3.8A) GAX  A 352 (-4.6A) GAX  A 352 (-3.9A) GAX  A 352 (-3.2A) None GAX  A 352 (-3.4A) GAX  A 352 (-3.2A)	0.62A	3tegA-2rhqA: 24.6	3tegA-2rhqA: 24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TEG_A_DAHA416_1 (PHENYLALANYL-TRNA SYNTHETASE, MITOCHONDRIAL)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	7 / 12	SER A 174 GLN A 214 PHE A 256 THR A 257 GLY A 290 ALA A 311 GLY A 313	GAX  A 352 (-2.8A) GAX  A 352 (-4.2A) GAX  A 352 (-4.6A) GAX  A 352 (-3.9A) None GAX  A 352 (-3.4A) GAX  A 352 (-3.2A)	0.81A	3tegA-2rhqA: 24.6	3tegA-2rhqA: 24.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TEG_A_DAHA416_1 (PHENYLALANYL-TRNA SYNTHETASE, MITOCHONDRIAL)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	7 / 12	SER A 174 GLU A 216 PHE A 256 THR A 257 GLY A 290 ALA A 311 GLY A 313	GAX  A 352 (-2.8A) GAX  A 352 (-3.7A) GAX  A 352 (-4.6A) GAX  A 352 (-3.9A) None GAX  A 352 (-3.4A) GAX  A 352 (-3.2A)	0.99A	3tegA-2rhqA: 24.6	3tegA-2rhqA: 24.20
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TEH_A_DAHA351_1 (PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	5 / 9	HIS A 172 SER A 174 GLN A 214 ALA A 311 GLY A 313	None GAX  A 352 (-2.8A) GAX  A 352 (-4.2A) GAX  A 352 (-3.4A) GAX  A 352 (-3.2A)	0.71A	3tehA-2rhqA: 28.4	3tehA-2rhqA: 36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TEH_A_DAHA351_1 (PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	5 / 9	HIS A 172 SER A 174 GLU A 216 ALA A 311 GLY A 313	None GAX  A 352 (-2.8A) GAX  A 352 (-3.7A) GAX  A 352 (-3.4A) GAX  A 352 (-3.2A)	0.79A	3tehA-2rhqA: 28.4	3tehA-2rhqA: 36.46
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	3TEH_A_DAHA351_1 (PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	5 / 9	HIS A 172 SER A 174 GLU A 216 VAL A 292 ALA A 311	None GAX  A 352 (-2.8A) GAX  A 352 (-3.7A) GAX  A 352 ( 4.5A) GAX  A 352 (-3.4A)	1.36A	3tehA-2rhqA: 28.4	3tehA-2rhqA: 36.46
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O8F_B_BRLB501_1 (PEROXISOME PROLIFERATOR-ACTIVAT ED RECEPTOR GAMMA)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	5 / 12	HIS A 172 LEU A 218 VAL A 220 MET A 181 LEU A 148	None GAX  A 352 ( 4.3A) None GAX  A 352 ( 4.8A) None	1.34A	4o8fB-2rhqA: undetectable	4o8fB-2rhqA: 21.47
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4S0V_A_SUVA2001_1 (HUMAN OREXIN RECEPTOR TYPE 2 FUSION PROTEIN TO P. ABYSII GLYCOGEN SYNTHASE)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	5 / 12	THR A 232 VAL A 236 VAL A 220 GLN A 177 GLU A 216	None None None GAX  A 352 (-4.0A) GAX  A 352 (-3.7A)	1.11A	4s0vA-2rhqA: undetectable	4s0vA-2rhqA: 19.74
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WNW_A_RTZA602_1 (CYTOCHROME P450 2D6)	2rhq	PHENYLALANYL-TRNA SYNTHETASE ALPHA CHAIN (Staphylococcus haemolyticus)	5 / 12	PHE A 310 LEU A 218 GLY A 127 LEU A 126 PHE A 123	None GAX  A 352 ( 4.3A) None None None	1.13A	4wnwA-2rhqA: undetectable	4wnwA-2rhqA: 19.42