SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GAQ'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_A_ZMRA1478_1 (NEURAMINIDASE)	1zlp	PETAL DEATH PROTEIN (Dianthus caryophyllus)	4 / 7	ASP A 107 SER A 66 SER A 257 ASN A 231	MG A 401 (-2.7A) None GAQ A 402 ( 3.8A) GAQ A 402 (-3.9A)	1.12A	2cmlA-1zlpA: undetectable	2cmlA-1zlpA: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2CML_D_ZMRD4478_1 (NEURAMINIDASE)	1zlp	PETAL DEATH PROTEIN (Dianthus caryophyllus)	4 / 8	ASP A 107 SER A 66 SER A 257 ASN A 231	MG A 401 (-2.7A) None GAQ A 402 ( 3.8A) GAQ A 402 (-3.9A)	1.12A	2cmlD-1zlpA: undetectable	2cmlD-1zlpA: 22.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2XZ5_C_ACHC1211_0 (SOLUBLE ACETYLCHOLINE RECEPTOR)	1zlp	PETAL DEATH PROTEIN (Dianthus caryophyllus)	4 / 8	ASP A 107 TYR A 262 TYR A 68 CYH A 144	MG A 401 (-2.7A) None GAQ A 402 ( 4.4A) GAQ A 402 (-1.6A)	1.24A	2xz5A-1zlpA: undetectable 2xz5C-1zlpA: undetectable	2xz5A-1zlpA: 18.65 2xz5C-1zlpA: 18.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MUG_A_VIVA301_1 (ALPHA-TOCOPHEROL TRANSFER PROTEIN)	1zlp	PETAL DEATH PROTEIN (Dianthus caryophyllus)	3 / 3	SER A 257 SER A 66 PHE A 207	GAQ A 402 ( 3.8A) None None	0.97A	5mugA-1zlpA: 1.8	5mugA-1zlpA: 21.91

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2CML_A_ZMRA1478_1","NEURAMINIDASE","1zlp","PETAL DEATH PROTEIN","Dianthus caryophyllus",4,"ASP A 107;SER A  66;SER A 257;ASN A 231"," MG A 401 (-2.7A);None;GAQ A 402 ( 3.8A);GAQ A 402 (-3.9A)","1.12A","2cmlA-1zlpA:undetectable",null],["2CML_D_ZMRD4478_1","NEURAMINIDASE","1zlp","PETAL DEATH PROTEIN","Dianthus caryophyllus",4,"ASP A 107;SER A  66;SER A 257;ASN A 231"," MG A 401 (-2.7A);None;GAQ A 402 ( 3.8A);GAQ A 402 (-3.9A)","1.12A","2cmlD-1zlpA:undetectable","2cmlA-1zlpA:22.60"],["2XZ5_C_ACHC1211_0","SOLUBLE ACETYLCHOLINE RECEPTOR","1zlp","PETAL DEATH PROTEIN","Dianthus caryophyllus",4,"ASP A 107;TYR A 262;TYR A  68;CYH A 144"," MG A 401 (-2.7A);None;GAQ A 402 ( 4.4A);GAQ A 402 (-1.6A)","1.24A","2xz5A-1zlpA:undetectable;2xz5C-1zlpA:undetectable","2cmlD-1zlpA:22.60"],["5MUG_A_VIVA301_1","ALPHA-TOCOPHEROL TRANSFER PROTEIN","1zlp","PETAL DEATH PROTEIN","Dianthus caryophyllus",3,"SER A 257;SER A  66;PHE A 207","GAQ A 402 ( 3.8A);None;None","0.97A","5mugA-1zlpA:1.8","2xz5A-1zlpA:18.65;2xz5C-1zlpA:18.65"]]