SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'GAE'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		3 / 3 ARG A  15
VAL A 338
THR A 304
 GAE  A 411 (-3.0A)
None
None
 0.83A 3k4vA-3hpfA:
undetectable		 3k4vA-3hpfA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3NDT_A_ROCA101_2
(PROTEASE)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		3 / 3 ARG A  15
VAL A 338
THR A 304
 GAE  A 411 (-3.0A)
None
None
 0.71A 3ndtA-3hpfA:
undetectable		 3ndtA-3hpfA:
12.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3TL9_A_ROCA401_2
(PROTEASE)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		3 / 3 ARG A  15
VAL A 338
THR A 304
 GAE  A 411 (-3.0A)
None
None
 0.87A 3tl9A-3hpfA:
undetectable		 3tl9A-3hpfA:
13.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3VXI_A_ASCA502_0
(DYP)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		4 / 5 ASN A  21
ARG A  15
PRO A 326
HIS A  23
 None
GAE  A 411 (-3.0A)
None
None
 1.33A 3vxiA-3hpfA:
0.0		 3vxiA-3hpfA:
23.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5A06_C_SORC1341_0
(ALDOSE-ALDOSE
OXIDOREDUCTASE)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		4 / 7 ARG A 162
PHE A  19
ASP A  42
TYR A 164
 GAE  A 411 (-3.0A)
None
MG  A 402 ( 3.1A)
None
 1.48A 5a06C-3hpfA:
undetectable		 5a06C-3hpfA:
22.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XPR_A_K86A1201_2
(ENDOTHELIN B
RECEPTOR,ENDOLYSIN,E
NDOTHELIN B RECEPTOR)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		4 / 4 ASP A 228
PRO A 223
GLU A 221
TYR A  89
 None
None
MG  A 401 ( 3.1A)
GAE  A 411 (-4.8A)
 1.41A 5xprA-3hpfA:
0.0		 5xprA-3hpfA:
21.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6EKZ_A_SNPA414_0
(AROMATIC
PEROXYGENASE)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		4 / 5 PHE A 271
VAL A 292
PRO A 323
VAL A 270
 GAE  A 411 (-4.8A)
None
None
None
 1.38A 6ekzA-3hpfA:
undetectable		 6ekzA-3hpfA:
10.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JMJ_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		4 / 5 GLY A 295
THR A 296
HIS A 246
SER A 195
 None
GAE  A 411 (-4.6A)
MG  A 401 ( 3.3A)
GAE  A 411 ( 4.8A)
 1.01A 6jmjA-3hpfA:
undetectable		 6jmjA-3hpfA:
18.39
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6JOG_A_ASCA201_0
(PHOSPHOPANTETHEINE
ADENYLYLTRANSFERASE)		 3hpf MUCONATE
CYCLOISOMERASE
(Oceanobacillus
iheyensis) 		4 / 6 GLY A 295
THR A 296
HIS A 246
SER A 195
 None
GAE  A 411 (-4.6A)
MG  A 401 ( 3.3A)
GAE  A 411 ( 4.8A)
 1.00A 6jogA-3hpfA:
undetectable		 6jogA-3hpfA:
18.39