SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'G4S'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2B9E_A_SAMA1201_0
(NOL1/NOP2/SUN DOMAIN
FAMILY, MEMBER 5
ISOFORM 2)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		5 / 12 PRO A  80
GLY A  79
ASN A  99
ASP A 112
SER A 453
 None
None
G4S  A 503 ( 3.4A)
None
None
 1.15A 2b9eA-6b0kA:
undetectable		 2b9eA-6b0kA:
undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_A_RBFA200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 TYR A 226
TRP A 133
ARG A 146
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.45A 2vxaA-6b0kA:
undetectable
2vxaC-6b0kA:
undetectable
2vxaE-6b0kA:
undetectable		 2vxaA-6b0kA:
17.65
2vxaC-6b0kA:
17.65
2vxaE-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_B_RBFB200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
TRP A 133
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.47A 2vxaA-6b0kA:
undetectable
2vxaB-6b0kA:
undetectable
2vxaK-6b0kA:
undetectable		 2vxaA-6b0kA:
17.65
2vxaB-6b0kA:
17.65
2vxaK-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_C_RBFC200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
TRP A 133
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.46A 2vxaB-6b0kA:
undetectable
2vxaC-6b0kA:
undetectable
2vxaG-6b0kA:
undetectable		 2vxaB-6b0kA:
17.65
2vxaC-6b0kA:
17.65
2vxaG-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_E_RBFE200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 ARG A 146
TYR A 226
TRP A 133
HIS A 134
 None
None
None
G4S  A 503 ( 4.2A)
 1.48A 2vxaD-6b0kA:
undetectable
2vxaE-6b0kA:
undetectable
2vxaL-6b0kA:
undetectable		 2vxaD-6b0kA:
17.65
2vxaE-6b0kA:
17.65
2vxaL-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2VXA_J_RBFJ200_1
(DODECIN)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 8 HIS A 134
TYR A 226
TRP A 133
ARG A 146
 G4S  A 503 ( 4.2A)
None
None
None
 1.46A 2vxaD-6b0kA:
undetectable
2vxaJ-6b0kA:
undetectable
2vxaL-6b0kA:
undetectable		 2vxaD-6b0kA:
17.65
2vxaJ-6b0kA:
17.65
2vxaL-6b0kA:
17.65
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_E_LFXE101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
GGTCATGAATGACTATGCAC
GTAA)		 6b0k IOTA-CARRAGEENAN
SULFATASE
(Pseudoalteromona
s) 		4 / 5 SER A 290
GLY A 158
THR A 102
GLU A 183
 None
G4S  A 503 ( 4.5A)
None
None
 1.21A 5btiA-6b0kA:
undetectable
5btiB-6b0kA:
undetectable		 5btiA-6b0kA:
9.54
5btiB-6b0kA:
15.81