SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FZ1'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	4iu6	METHIONINE AMINOPEPTIDASE 1 (Homo sapiens)	4 / 7	CYH A 203 HIS A 212 HIS A 310 TRP A 353	FZ1 A 405 (-3.5A) CO A 403 ( 3.1A) FZ1 A 405 (-3.4A) None	0.73A	1yvmA-4iu6A: 38.7	1yvmA-4iu6A: 33.33
Available target for annotated drug, i.e. matched protein structure has more than 30% sequence identity to known drug target.	1YVM_A_TMGA501_1 (METHIONINE AMINOPEPTIDASE)	4iu6	METHIONINE AMINOPEPTIDASE 1 (Homo sapiens)	4 / 7	TYR A 195 CYH A 203 HIS A 212 HIS A 310	FZ1 A 405 (-4.4A) FZ1 A 405 (-3.5A) CO A 403 ( 3.1A) FZ1 A 405 (-3.4A)	0.44A	1yvmA-4iu6A: 38.7	1yvmA-4iu6A: 33.33
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UZZ_A_TESA501_1 (3-OXO-5-BETA-STEROID 4-DEHYDROGENASE)	4iu6	METHIONINE AMINOPEPTIDASE 1 (Homo sapiens)	4 / 7	TYR A 117 TYR A 195 HIS A 310 MET A 148	None FZ1 A 405 (-4.4A) FZ1 A 405 (-3.4A) None	1.24A	3uzzA-4iu6A: undetectable	3uzzA-4iu6A: 23.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3UZZ_B_ASDB501_1 (3-OXO-5-BETA-STEROID 4-DEHYDROGENASE)	4iu6	METHIONINE AMINOPEPTIDASE 1 (Homo sapiens)	4 / 8	TYR A 117 TYR A 195 HIS A 310 MET A 148	None FZ1 A 405 (-4.4A) FZ1 A 405 (-3.4A) None	1.32A	3uzzB-4iu6A: undetectable	3uzzB-4iu6A: 23.11

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1YVM_A_TMGA501_1","METHIONINE AMINOPEPTIDASE","4iu6","METHIONINE AMINOPEPTIDASE 1","Homo sapiens",4,"CYH A 203;HIS A 212;HIS A 310;TRP A 353","FZ1 A 405 (-3.5A); CO A 403 ( 3.1A);FZ1 A 405 (-3.4A);None","0.73A","1yvmA-4iu6A:38.7",null],["1YVM_A_TMGA501_1","METHIONINE AMINOPEPTIDASE","4iu6","METHIONINE AMINOPEPTIDASE 1","Homo sapiens",4,"TYR A 195;CYH A 203;HIS A 212;HIS A 310","FZ1 A 405 (-4.4A);FZ1 A 405 (-3.5A); CO A 403 ( 3.1A);FZ1 A 405 (-3.4A)","0.44A","1yvmA-4iu6A:38.7","1yvmA-4iu6A:33.33"],["3UZZ_A_TESA501_1","3-OXO-5-BETA-STEROID 4-DEHYDROGENASE","4iu6","METHIONINE AMINOPEPTIDASE 1","Homo sapiens",4,"TYR A 117;TYR A 195;HIS A 310;MET A 148","None;FZ1 A 405 (-4.4A);FZ1 A 405 (-3.4A);None","1.24A","3uzzA-4iu6A:undetectable","1yvmA-4iu6A:33.33"],["3UZZ_B_ASDB501_1","3-OXO-5-BETA-STEROID 4-DEHYDROGENASE","4iu6","METHIONINE AMINOPEPTIDASE 1","Homo sapiens",4,"TYR A 117;TYR A 195;HIS A 310;MET A 148","None;FZ1 A 405 (-4.4A);FZ1 A 405 (-3.4A);None","1.32A","3uzzB-4iu6A:undetectable","3uzzA-4iu6A:23.11"]]