SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FUB'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2BTE_A_LEUA1894_0 (AMINOACYL-TRNA SYNTHETASE)	4n2r	ALPHA-L-ARABINOFURAN OSIDASE UMABF62A (Ustilago maydis)	4 / 8	SER A 51 TYR A 58 TYR A 296 HIS A 261	FUB A 402 ( 4.4A) FUB A 402 ( 3.8A) None CA A 401 (-3.6A)	1.23A	2bteA-4n2rA: undetectable	2bteA-4n2rA: 16.44
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FK8_A_SAMA302_1 (METHOXY MYCOLIC ACID SYNTHASE 4)	4n2r	ALPHA-L-ARABINOFURAN OSIDASE UMABF62A (Ustilago maydis)	3 / 3	SER A 51 THR A 145 GLN A 198	FUB A 402 ( 4.4A) None CA A 401 (-2.9A)	0.79A	2fk8A-4n2rA: undetectable	2fk8A-4n2rA: 19.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Q6K_A_ADNA699_1 (CHLORINASE)	4n2r	ALPHA-L-ARABINOFURAN OSIDASE UMABF62A (Ustilago maydis)	4 / 7	ASP A 36 PHE A 37 TYR A 58 TYR A 52	FUB A 402 ( 2.8A) None FUB A 402 ( 3.8A) None	1.21A	2q6kA-4n2rA: undetectable	2q6kA-4n2rA: 20.27
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4FZV_A_SAMA401_1 (PUTATIVE METHYLTRANSFERASE NSUN4)	5ocp	- (-)	3 / 3	ASP A 88 ARG A 89 ASP A 223	AHR A 407 ( 2.6A) FUB A 408 ( 3.9A) AHR A 407 ( 2.8A)	0.87A	4fzvA-5ocpA: undetectable	4fzvA-5ocpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_A_SAMA401_1 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	5ocp	- (-)	3 / 3	ASP A 88 ARG A 89 ASP A 223	AHR A 407 ( 2.6A) FUB A 408 ( 3.9A) AHR A 407 ( 2.8A)	0.85A	5zvgA-5ocpA: undetectable	5zvgA-5ocpA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5ZVG_B_SAMB401_1 (389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN)	5ocp	- (-)	3 / 3	ASP A 88 ARG A 89 ASP A 223	AHR A 407 ( 2.6A) FUB A 408 ( 3.9A) AHR A 407 ( 2.8A)	0.88A	5zvgB-5ocpA: 2.2	5zvgB-5ocpA: undetectable

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["2BTE_A_LEUA1894_0","AMINOACYL-TRNA SYNTHETASE","4n2r","ALPHA-L-ARABINOFURANOSIDASE UMABF62A","Ustilago maydis",4,"SER A  51;TYR A  58;TYR A 296;HIS A 261","FUB A 402 ( 4.4A);FUB A 402 ( 3.8A);None; CA A 401 (-3.6A)","1.23A","2bteA-4n2rA:undetectable",null],["2FK8_A_SAMA302_1","METHOXY MYCOLIC ACID SYNTHASE 4","4n2r","ALPHA-L-ARABINOFURANOSIDASE UMABF62A","Ustilago maydis",3,"SER A  51;THR A 145;GLN A 198","FUB A 402 ( 4.4A);None; CA A 401 (-2.9A)","0.79A","2fk8A-4n2rA:undetectable","2bteA-4n2rA:16.44"],["2Q6K_A_ADNA699_1","CHLORINASE","4n2r","ALPHA-L-ARABINOFURANOSIDASE UMABF62A","Ustilago maydis",4,"ASP A  36;PHE A  37;TYR A  58;TYR A  52","FUB A 402 ( 2.8A);None;FUB A 402 ( 3.8A);None","1.21A","2q6kA-4n2rA:undetectable","2fk8A-4n2rA:19.71"],["4FZV_A_SAMA401_1","PUTATIVE METHYLTRANSFERASE NSUN4","5ocp","-","-",3,"ASP A  88;ARG A  89;ASP A 223","AHR A 407 ( 2.6A);FUB A 408 ( 3.9A);AHR A 407 ( 2.8A)","0.87A","4fzvA-5ocpA:undetectable","2q6kA-4n2rA:20.27"],["5ZVG_A_SAMA401_1","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","5ocp","-","-",3,"ASP A  88;ARG A  89;ASP A 223","AHR A 407 ( 2.6A);FUB A 408 ( 3.9A);AHR A 407 ( 2.8A)","0.85A","5zvgA-5ocpA:undetectable","4fzvA-5ocpA:undetectable"],["5ZVG_B_SAMB401_1","389AA LONG HYPOTHETICAL NUCLEOLAR PROTEIN","5ocp","-","-",3,"ASP A  88;ARG A  89;ASP A 223","AHR A 407 ( 2.6A);FUB A 408 ( 3.9A);AHR A 407 ( 2.8A)","0.88A","5zvgB-5ocpA:2.2","5zvgA-5ocpA:undetectable"]]