SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FTG'
DrReposER ID / Desc. | Hit PDBID |
Hit Macromolecule |
Res. Matches |
Interface | HETATM | RMSD | Dali Z-score |
Seq. Identity (%) |
View | Dock | |
---|---|---|---|---|---|---|---|---|---|---|---|
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 2YVL_A_SAMA601_0 (HYPOTHETICAL PROTEIN) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 12 | ILE A 197GLY A 192GLY A 194SER A 195ALA A 215 | FTG A 501 (-4.7A)FTG A 501 (-3.2A)FTG A 501 ( 3.9A)NoneFTG A 501 (-3.4A) | 1.11A | 2yvlA-6d2lA:10.7 | 2yvlA-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3EKT_B_017B200_2 (PROTEASE) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 9 | ALA A 203VAL A 188ILE A 197ALA A 212ILE A 210 | NoneNoneFTG A 501 (-4.7A)NoneNone | 1.05A | 3ektB-6d2lA:undetectable | 3ektB-6d2lA:17.35 | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G88_A_SAMA303_0 (RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE G) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 11 | GLY A 192GLY A 194ALA A 215GLU A 243ARG A 168 | FTG A 501 (-3.2A)FTG A 501 ( 3.9A)FTG A 501 (-3.4A)FTG A 501 (-3.2A)FTG A 501 (-3.3A) | 0.78A | 3g88A-6d2lA:9.1 | 3g88A-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G88_B_SAMB303_0 (RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE G) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 11 | GLY A 192GLY A 194ALA A 215GLU A 243ARG A 168 | FTG A 501 (-3.2A)FTG A 501 ( 3.9A)FTG A 501 (-3.4A)FTG A 501 (-3.2A)FTG A 501 (-3.3A) | 0.80A | 3g88B-6d2lA:9.4 | 3g88B-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G89_A_SAMA303_0 (RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE G) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 12 | GLY A 192GLY A 194ALA A 215GLU A 243ARG A 168 | FTG A 501 (-3.2A)FTG A 501 ( 3.9A)FTG A 501 (-3.4A)FTG A 501 (-3.2A)FTG A 501 (-3.3A) | 0.82A | 3g89A-6d2lA:9.8 | 3g89A-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G89_B_SAMB303_0 (RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE G) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 11 | GLY A 192GLY A 194ALA A 215GLU A 243ARG A 168 | FTG A 501 (-3.2A)FTG A 501 ( 3.9A)FTG A 501 (-3.4A)FTG A 501 (-3.2A)FTG A 501 (-3.3A) | 0.83A | 3g89B-6d2lA:9.5 | 3g89B-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G8B_A_SAMA303_0 (RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE G) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 12 | GLY A 192GLY A 194ALA A 215GLU A 243ARG A 168 | FTG A 501 (-3.2A)FTG A 501 ( 3.9A)FTG A 501 (-3.4A)FTG A 501 (-3.2A)FTG A 501 (-3.3A) | 0.83A | 3g8bA-6d2lA:9.6 | 3g8bA-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3G8B_B_SAMB303_0 (RIBOSOMAL RNA SMALLSUBUNITMETHYLTRANSFERASE G) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 12 | GLY A 192GLY A 194ALA A 215GLU A 243ARG A 168 | FTG A 501 (-3.2A)FTG A 501 ( 3.9A)FTG A 501 (-3.4A)FTG A 501 (-3.2A)FTG A 501 (-3.3A) | 0.84A | 3g8bB-6d2lA:9.2 | 3g8bB-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 3VYW_C_SAMC401_1 (MNMC2) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 4 / 6 | GLY A 194GLU A 214ASP A 190GLU A 243 | FTG A 501 ( 3.9A)FTG A 501 (-2.5A)NoneFTG A 501 (-3.2A) | 0.78A | 3vywC-6d2lA:7.0 | 3vywC-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 4BLV_A_SAMA1281_0 (RIBOSOMAL RNA LARGESUBUNITMETHYLTRANSFERASE J) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 12 | TYR A 355GLY A 290HIS A 293ASP A 291GLY A 260 | NoneNoneSO4 A 502 ( 4.8A)NoneFTG A 501 ( 4.3A) | 1.14A | 4blvA-6d2lA:8.1 | 4blvA-6d2lA:undetectable | ||
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site. | 5C0O_E_SAME301_0 (TRNA(ADENINE(58)-N(1))-METHYLTRANSFERASETRMI) |
6d2l | HISTONE-ARGININEMETHYLTRANSFERASECARM1 (Homosapiens) | 5 / 12 | GLY A 192GLY A 194LEU A 198ALA A 215GLU A 243 | FTG A 501 (-3.2A)FTG A 501 ( 3.9A)NoneFTG A 501 (-3.4A)FTG A 501 (-3.2A) | 0.84A | 5c0oE-6d2lA:10.4 | 5c0oE-6d2lA:undetectable |