SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FSX'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4EAT_A_BEZA1000_0
(BENZOATE-COENZYME A
LIGASE)		 1e3d [NIFE] HYDROGENASE
SMALL SUBUNIT
(Desulfovibrio
desulfuricans) 		4 / 7 ALA A 122
GLY A  76
ILE A 133
GLY A 132
 None
FSX  A 269 ( 4.1A)
None
None
 0.66A 4eatA-1e3dA:
undetectable		 4eatA-1e3dA:
20.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5EWU_A_BEZA1401_0
(MAGNESIUM-CHELATASE
SUBUNIT CHLH,
CHLOROPLASTIC)		 3ze6 PERIPLASMIC [NIFESE]
HYDROGENASE, SMALL
SUBUNIT
(Desulfovibrio
vulgaris) 		4 / 6 GLY A  20
THR A  19
VAL A  23
HIS A  46
 FSX  A 287 ( 3.6A)
None
None
SBY  A1285 (-3.5A)
 1.02A 5ewuA-3ze6A:
undetectable		 5ewuA-3ze6A:
22.89
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IGJ_A_CTYA402_2
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E)		 1e3d [NIFE] HYDROGENASE
LARGE SUBUNIT
[NIFE] HYDROGENASE
SMALL SUBUNIT
(Desulfovibrio
desulfuricans) 		4 / 5 PRO A 151
HIS B 112
LEU A  35
TYR A  28
 FSX  A 269 (-3.8A)
None
None
None
 1.37A 5igjA-1e3dA:
undetectable		 5igjA-1e3dA:
19.34
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5OCS_A_ACTA402_0
(PUTATIVE
NADH-DEPENTDENT
FLAVIN
OXIDOREDUCTASE)		 1e3d [NIFE] HYDROGENASE
SMALL SUBUNIT
(Desulfovibrio
desulfuricans) 		4 / 5 CYH A  20
ILE A 111
HIS A  13
HIS A  45
 FSX  A 269 (-1.5A)
None
None
None
 1.29A 5ocsA-1e3dA:
undetectable		 5ocsA-1e3dA:
20.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Y2T_A_8LXA501_0
(PEROXISOME
PROLIFERATOR-ACTIVAT
ED RECEPTOR GAMMA)		 1e3d [NIFE] HYDROGENASE
SMALL SUBUNIT
[NIFE] HYDROGENASE
LARGE SUBUNIT
(Desulfovibrio
desulfuricans;
Desulfovibrio
desulfuricans) 		5 / 12 LEU B  47
GLY A  76
LEU A 102
ILE A  78
MET A  94
 None
FSX  A 269 ( 4.1A)
None
None
None
 1.07A 5y2tA-1e3dB:
0.0		 5y2tA-1e3dB:
undetectable