SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FS5'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1V55_P_CHDP4525_0
(CYTOCHROME C OXIDASE
POLYPEPTIDE I
CYTOCHROME C OXIDASE
POLYPEPTIDE III)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 7 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.15A 1v55C-4jc0A:
undetectable
1v55N-4jc0A:
undetectable
1v55P-4jc0A:
undetectable		 1v55C-4jc0A:
19.73
1v55N-4jc0A:
19.82
1v55P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2FL5_B_RBFB202_1
(IMMUNOGLOBULIN IGG1
LAMBDA LIGHT CHAIN
IMMUNOGLOBULIN IGG1
HEAVY CHAIN)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		5 / 11 GLY A   9
TYR A 141
GLU A 396
VAL A 190
GLU A 135
 FS5  A 501 (-3.7A)
None
None
None
None
 1.44A 2fl5A-4jc0A:
undetectable
2fl5B-4jc0A:
undetectable
2fl5F-4jc0A:
undetectable		 2fl5A-4jc0A:
19.26
2fl5B-4jc0A:
22.11
2fl5F-4jc0A:
22.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2J9C_C_ACTC1120_0
(HYPOTHETICAL
NITROGEN REGULATORY
PII-LIKE PROTEIN
MJ0059)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		3 / 3 LYS A  12
TYR A 227
PRO A  11
 FS5  A 501 (-2.9A)
None
None
 1.49A 2j9cC-4jc0A:
undetectable		 2j9cC-4jc0A:
17.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Y69_N_CHDN1517_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.14A 2y69C-4jc0A:
undetectable
2y69N-4jc0A:
undetectable
2y69P-4jc0A:
undetectable		 2y69C-4jc0A:
19.73
2y69N-4jc0A:
19.82
2y69P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ABM_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.13A 3abmA-4jc0A:
undetectable
3abmC-4jc0A:
undetectable
3abmP-4jc0A:
undetectable		 3abmA-4jc0A:
19.82
3abmC-4jc0A:
19.73
3abmP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASN_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.15A 3asnC-4jc0A:
undetectable
3asnN-4jc0A:
undetectable
3asnP-4jc0A:
undetectable		 3asnC-4jc0A:
19.73
3asnN-4jc0A:
19.82
3asnP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.19A 3asoA-4jc0A:
undetectable
3asoC-4jc0A:
undetectable
3asoP-4jc0A:
undetectable		 3asoA-4jc0A:
19.82
3asoC-4jc0A:
19.73
3asoP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3ASO_P_CHDP1525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.17A 3asoC-4jc0A:
undetectable
3asoN-4jc0A:
undetectable
3asoP-4jc0A:
undetectable		 3asoC-4jc0A:
19.73
3asoN-4jc0A:
19.82
3asoP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_C_CHDC306_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.09A 3wg7A-4jc0A:
undetectable
3wg7C-4jc0A:
undetectable
3wg7P-4jc0A:
undetectable		 3wg7A-4jc0A:
19.82
3wg7C-4jc0A:
19.73
3wg7P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3WG7_P_CHDP307_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.13A 3wg7C-4jc0A:
undetectable
3wg7N-4jc0A:
undetectable
3wg7P-4jc0A:
undetectable		 3wg7C-4jc0A:
19.73
3wg7N-4jc0A:
19.82
3wg7P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3X2Q_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.13A 3x2qA-4jc0A:
undetectable
3x2qC-4jc0A:
undetectable
3x2qP-4jc0A:
undetectable		 3x2qA-4jc0A:
19.82
3x2qC-4jc0A:
19.73
3x2qP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B1A_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.12A 5b1aA-4jc0A:
undetectable
5b1aC-4jc0A:
undetectable
5b1aP-4jc0A:
undetectable		 5b1aA-4jc0A:
19.82
5b1aC-4jc0A:
19.73
5b1aP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5B3S_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.10A 5b3sA-4jc0A:
undetectable
5b3sC-4jc0A:
undetectable
5b3sP-4jc0A:
undetectable		 5b3sA-4jc0A:
19.82
5b3sC-4jc0A:
19.73
5b3sP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IY5_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.18A 5iy5C-4jc0A:
undetectable
5iy5N-4jc0A:
undetectable
5iy5P-4jc0A:
undetectable		 5iy5C-4jc0A:
19.59
5iy5N-4jc0A:
19.82
5iy5P-4jc0A:
19.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5N1T_W_CUW201_0
(COPC)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		3 / 3 HIS A 232
ASP A 193
HIS A 229
 None
FS5  A 501 ( 4.8A)
FS5  A 501 ( 4.9A)
 0.96A 5n1tW-4jc0A:
undetectable		 5n1tW-4jc0A:
17.81
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.10A 5w97A-4jc0A:
undetectable
5w97C-4jc0A:
undetectable
5w97c-4jc0A:
undetectable		 5w97A-4jc0A:
19.82
5w97C-4jc0A:
19.73
5w97c-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5W97_C_CHDC302_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 7 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.10A 5w97C-4jc0A:
undetectable
5w97a-4jc0A:
undetectable
5w97c-4jc0A:
undetectable		 5w97C-4jc0A:
19.73
5w97a-4jc0A:
19.82
5w97c-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.13A 5wauA-4jc0A:
undetectable
5wauC-4jc0A:
undetectable
5wauc-4jc0A:
undetectable		 5wauA-4jc0A:
19.82
5wauC-4jc0A:
19.73
5wauc-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5WAU_C_CHDC303_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 7 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.14A 5wauC-4jc0A:
undetectable
5waua-4jc0A:
undetectable
5wauc-4jc0A:
undetectable		 5wauC-4jc0A:
19.73
5waua-4jc0A:
19.82
5wauc-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X19_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.16A 5x19A-4jc0A:
undetectable
5x19C-4jc0A:
undetectable
5x19P-4jc0A:
undetectable		 5x19A-4jc0A:
19.82
5x19C-4jc0A:
19.73
5x19P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5X1F_C_CHDC305_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 7 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.18A 5x1fA-4jc0A:
undetectable
5x1fC-4jc0A:
undetectable
5x1fP-4jc0A:
undetectable		 5x1fA-4jc0A:
19.82
5x1fC-4jc0A:
19.73
5x1fP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.12A 5xdqA-4jc0A:
undetectable
5xdqC-4jc0A:
undetectable
5xdqP-4jc0A:
undetectable		 5xdqA-4jc0A:
19.82
5xdqC-4jc0A:
19.73
5xdqP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDQ_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.16A 5xdqC-4jc0A:
undetectable
5xdqN-4jc0A:
undetectable
5xdqP-4jc0A:
undetectable		 5xdqC-4jc0A:
19.73
5xdqN-4jc0A:
19.82
5xdqP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5XDX_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.19A 5xdxC-4jc0A:
undetectable
5xdxN-4jc0A:
undetectable
5xdxP-4jc0A:
undetectable		 5xdxC-4jc0A:
19.55
5xdxN-4jc0A:
19.82
5xdxP-4jc0A:
19.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.10A 5z84A-4jc0A:
undetectable
5z84C-4jc0A:
undetectable
5z84P-4jc0A:
undetectable		 5z84A-4jc0A:
19.82
5z84C-4jc0A:
19.73
5z84P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z84_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 7 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.16A 5z84C-4jc0A:
undetectable
5z84N-4jc0A:
undetectable
5z84P-4jc0A:
undetectable		 5z84C-4jc0A:
19.73
5z84N-4jc0A:
19.82
5z84P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.09A 5z85A-4jc0A:
undetectable
5z85C-4jc0A:
undetectable
5z85P-4jc0A:
undetectable		 5z85A-4jc0A:
19.82
5z85C-4jc0A:
19.73
5z85P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z85_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 7 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.15A 5z85C-4jc0A:
undetectable
5z85N-4jc0A:
undetectable
5z85P-4jc0A:
undetectable		 5z85C-4jc0A:
19.73
5z85N-4jc0A:
19.82
5z85P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.09A 5z86A-4jc0A:
undetectable
5z86C-4jc0A:
undetectable
5z86P-4jc0A:
undetectable		 5z86A-4jc0A:
19.82
5z86C-4jc0A:
19.73
5z86P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5Z86_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.17A 5z86C-4jc0A:
undetectable
5z86N-4jc0A:
undetectable
5z86P-4jc0A:
undetectable		 5z86C-4jc0A:
19.73
5z86N-4jc0A:
19.82
5z86P-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.12A 5zcoA-4jc0A:
undetectable
5zcoC-4jc0A:
undetectable
5zcoP-4jc0A:
undetectable		 5zcoA-4jc0A:
19.82
5zcoC-4jc0A:
19.73
5zcoP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCO_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.14A 5zcoC-4jc0A:
undetectable
5zcoN-4jc0A:
undetectable
5zcoP-4jc0A:
undetectable		 5zcoC-4jc0A:
19.73
5zcoN-4jc0A:
19.82
5zcoP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.11A 5zcpA-4jc0A:
undetectable
5zcpC-4jc0A:
undetectable
5zcpP-4jc0A:
undetectable		 5zcpA-4jc0A:
19.82
5zcpC-4jc0A:
19.73
5zcpP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCP_P_CHDP301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 LEU A 164
ASP A 193
THR A 194
TYR A 197
 None
FS5  A 501 ( 4.8A)
None
None
 1.14A 5zcpC-4jc0A:
undetectable
5zcpN-4jc0A:
undetectable
5zcpP-4jc0A:
undetectable		 5zcpC-4jc0A:
19.73
5zcpN-4jc0A:
19.82
5zcpP-4jc0A:
19.73
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5ZCQ_C_CHDC301_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 4jc0 RIBOSOMAL PROTEIN
S12
METHYLTHIOTRANSFERAS
E RIMO
(Thermotoga
maritima) 		4 / 8 ASP A 193
THR A 194
TYR A 197
LEU A 164
 FS5  A 501 ( 4.8A)
None
None
None
 1.09A 5zcqA-4jc0A:
undetectable
5zcqC-4jc0A:
undetectable
5zcqP-4jc0A:
undetectable		 5zcqA-4jc0A:
19.82
5zcqC-4jc0A:
19.73
5zcqP-4jc0A:
19.73