SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FPQ'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NYR_B_SVRB401_3
(NAD-DEPENDENT
DEACETYLASE
SIRTUIN-5)		 3vk5 MOEO5
(Streptomyces
viridosporus) 		5 / 12 PHE A 160
GLY A 161
ASN A 204
VAL A 227
TYR A 201
 None
None
None
None
FPQ  A 900 (-3.8A)
 1.44A 2nyrB-3vk5A:
undetectable		 2nyrB-3vk5A:
24.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q6O_A_SAMA500_0
(HYPOTHETICAL PROTEIN)		 3vk5 MOEO5
(Streptomyces
viridosporus) 		4 / 7 VAL A  95
ALA A  64
PRO A 118
THR A 155
 None
None
FPQ  A 900 ( 4.7A)
None
 1.08A 2q6oA-3vk5A:
undetectable		 2q6oA-3vk5A:
24.84