SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FOK'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1TV8_B_SAMB2501_0
(MOLYBDENUM COFACTOR
BIOSYNTHESIS PROTEIN
A)		 1tl7 ADENYLATE CYCLASE,
TYPE V
(Canis
lupus) 		4 / 7 TYR A 443
THR A 529
THR A 532
VAL A 445
 FOK  A 101 (-4.4A)
None
None
None
 1.16A 1tv8B-1tl7A:
undetectable		 1tv8B-1tl7A:
21.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1UPF_A_URFA999_1
(URACIL
PHOSPHORIBOSYLTRANSF
ERASE)		 1tl7 ADENYLATE CYCLASE,
TYPE V
(Canis
lupus) 		4 / 5 ALA A 514
TYR A 443
ILE A 392
ASP A 505
 None
FOK  A 101 (-4.4A)
None
FOK  A 101 ( 3.9A)
 1.13A 1upfA-1tl7A:
undetectable		 1upfA-1tl7A:
22.82
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1WRL_D_TFPD207_1
(TROPONIN C, SLOW
SKELETAL AND CARDIAC
MUSCLES)		 1tl7 ADENYLATE CYCLASE,
TYPE V
(Canis
lupus) 		4 / 8 SER A 508
PHE A 394
LEU A 554
SER A 489
 None
FOK  A 101 (-4.9A)
None
None
 1.03A 1wrlC-1tl7A:
undetectable
1wrlD-1tl7A:
undetectable		 1wrlC-1tl7A:
18.26
1wrlD-1tl7A:
18.26