SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FEL'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2Q0I_A_BEZA990_0
(QUINOLONE SIGNAL
RESPONSE PROTEIN)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		4 / 8 ASP A 272
ASP A 154
SER A 251
HIS A 248
 None
None
FEL  A 500 ( 4.3A)
FEL  A 500 ( 4.8A)
 0.84A 2q0iA-1f1xA:
undetectable		 2q0iA-1f1xA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B6R_B_CRNB603_1
(CREATINE KINASE
B-TYPE)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		4 / 6 THR A 198
VAL A 199
GLU A 267
SER A 251
 None
None
FEL  A 500 (-2.4A)
FEL  A 500 ( 4.3A)
 1.19A 3b6rB-1f1xA:
undetectable		 3b6rB-1f1xA:
22.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B9L_A_AZZA1009_1
(SERUM ALBUMIN)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		4 / 8 TYR A 255
SER A 251
HIS A 214
ARG A 243
 None
FEL  A 500 ( 4.3A)
FEL  A 500 (-3.3A)
None
 1.04A 3b9lA-1f1xA:
0.0		 3b9lA-1f1xA:
18.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 11 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
 0.60A 4ir0A-1f1xA:
7.4
4ir0B-1f1xA:
7.6		 4ir0A-1f1xA:
19.51
4ir0B-1f1xA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4IR0_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
 0.55A 4ir0A-1f1xA:
7.4
4ir0B-1f1xA:
7.6		 4ir0A-1f1xA:
19.51
4ir0B-1f1xA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 12 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
 0.54A 4jd1A-1f1xA:
7.5
4jd1B-1f1xA:
7.4		 4jd1A-1f1xA:
19.51
4jd1B-1f1xA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JD1_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB 2)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 12 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
 0.67A 4jd1A-1f1xA:
7.5
4jd1B-1f1xA:
7.4		 4jd1A-1f1xA:
19.51
4jd1B-1f1xA:
19.51
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 12 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
 0.53A 4jh3A-1f1xA:
7.1
4jh3B-1f1xA:
7.6		 4jh3A-1f1xA:
18.01
4jh3B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH3_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
 0.51A 4jh3A-1f1xA:
7.1
4jh3B-1f1xA:
7.6		 4jh3A-1f1xA:
18.01
4jh3B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 11 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
 0.45A 4jh4A-1f1xA:
7.6
4jh4B-1f1xA:
7.4		 4jh4A-1f1xA:
18.01
4jh4B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH4_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
 0.47A 4jh4A-1f1xA:
7.6
4jh4B-1f1xA:
7.4		 4jh4A-1f1xA:
18.01
4jh4B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 11 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
 0.49A 4jh5A-1f1xA:
7.6
4jh5B-1f1xA:
7.3		 4jh5A-1f1xA:
18.01
4jh5B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH5_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 11 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
 0.50A 4jh5A-1f1xA:
7.6
4jh5B-1f1xA:
7.3		 4jh5A-1f1xA:
18.01
4jh5B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_A_FCNA202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 10 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
 0.52A 4jh6A-1f1xA:
7.6
4jh6B-1f1xA:
7.4		 4jh6A-1f1xA:
18.01
4jh6B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH6_B_FCNB202_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 10 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
 0.53A 4jh6A-1f1xA:
7.6
4jh6B-1f1xA:
7.4		 4jh6A-1f1xA:
18.01
4jh6B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_A_FCNA204_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 10 HIS A 214
TYR A 257
GLU A 267
HIS A 155
ALA A 203
 FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
 0.50A 4jh8A-1f1xA:
7.6
4jh8B-1f1xA:
7.1		 4jh8A-1f1xA:
18.01
4jh8B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4JH8_B_FCNB203_1
(METALLOTHIOL
TRANSFERASE FOSB)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		5 / 10 HIS A 155
ALA A 203
HIS A 214
TYR A 257
GLU A 267
 FEL  A 500 (-3.3A)
FEL  A 500 ( 4.2A)
FEL  A 500 (-3.3A)
FEL  A 500 (-4.7A)
FEL  A 500 (-2.4A)
 0.50A 4jh8A-1f1xA:
7.6
4jh8B-1f1xA:
7.1		 4jh8A-1f1xA:
18.01
4jh8B-1f1xA:
18.01
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5IWU_A_ERYA404_1
(MACROLIDE
2'-PHOSPHOTRANSFERAS
E II)		 1f1x HOMOPROTOCATECHUATE
2,3-DIOXYGENASE
(Brevibacterium
fuscum) 		4 / 6 GLY A 249
ASP A 154
ILE A 268
TYR A 257
 None
None
None
FEL  A 500 (-4.7A)
 0.86A 5iwuA-1f1xA:
undetectable		 5iwuA-1f1xA:
21.39