SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FEC'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4FGL_A_CLQA303_0
(RIBOSYLDIHYDRONICOTI
NAMIDE DEHYDROGENASE
[QUINONE])		 5loq PUTATIVE
HEME-DEPENDENT
PEROXIDASE LMO2113
(Listeria
monocytogenes) 		5 / 12 GLY A 191
TYR A 104
GLU A 109
ILE A 189
VAL A   5
 None
None
FEC  A 302 ( 4.8A)
FEC  A 302 ( 4.4A)
None
 1.21A 4fglA-5loqA:
undetectable
4fglB-5loqA:
undetectable		 4fglA-5loqA:
22.52
4fglB-5loqA:
22.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4L3G_F_ACTF401_0
(METHYLAMINE
DEHYDROGENASE HEAVY
CHAIN)		 1nf6 BACTERIOFERRITIN
(Desulfovibrio
desulfuricans) 		3 / 3 ARG A  20
LEU A  24
GLU A  23
 FEC  A1005 (-2.7A)
None
None
 0.72A 4l3gF-1nf6A:
undetectable		 4l3gF-1nf6A:
18.11
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5loq PUTATIVE
HEME-DEPENDENT
PEROXIDASE LMO2113
(Listeria
monocytogenes) 		4 / 6 SER A 103
GLY A 190
THR A   7
GLU A 109
 None
None
None
FEC  A 302 ( 4.8A)
 1.08A 5btcA-5loqA:
undetectable
5btcC-5loqA:
1.2
5btcD-5loqA:
undetectable		 5btcA-5loqA:
21.04
5btcC-5loqA:
21.04
5btcD-5loqA:
23.40
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTC_G_CPFG102_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5loq PUTATIVE
HEME-DEPENDENT
PEROXIDASE LMO2113
(Listeria
monocytogenes) 		4 / 6 SER A 103
GLY A 190
THR A   7
GLU A 109
 None
None
None
FEC  A 302 ( 4.8A)
 1.07A 5btcA-5loqA:
undetectable
5btcB-5loqA:
undetectable
5btcC-5loqA:
1.2		 5btcA-5loqA:
21.04
5btcB-5loqA:
23.40
5btcC-5loqA:
21.04
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5BTI_F_LFXF101_1
(DNA GYRASE SUBUNIT A
DNA GYRASE SUBUNIT B
DNA SUBSTRATE 24-MER
TTACGTGCATAGTCATTCAT
GACC)		 5loq PUTATIVE
HEME-DEPENDENT
PEROXIDASE LMO2113
(Listeria
monocytogenes) 		4 / 5 SER A 103
GLY A 190
THR A   7
GLU A 109
 None
None
None
FEC  A 302 ( 4.8A)
 1.03A 5btiC-5loqA:
undetectable
5btiD-5loqA:
undetectable		 5btiC-5loqA:
21.04
5btiD-5loqA:
23.40