SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FDP'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1ZQ9_A_SAMA4000_1
(PROBABLE
DIMETHYLADENOSINE
TRANSFERASE)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		3 / 3 GLY A 768
GLU A 827
ASN A 726
 FDP  A   1 (-3.7A)
FDP  A   1 (-2.8A)
FDP  A   1 (-3.7A)
 0.61A 1zq9A-3o8oA:
undetectable		 1zq9A-3o8oA:
16.79
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3MDT_B_VORB506_1
(CHOLESTEROL
24-HYDROXYLASE)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA
(Saccharomyces
cerevisiae) 		5 / 11 TYR B 767
LEU B 768
SER B 718
ALA B 598
ALA B 736
 None
None
FDP  B   2 (-2.5A)
None
None
 1.10A 3mdtB-3o8oB:
undetectable		 3mdtB-3o8oB:
20.13
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5F9Z_A_HFGA702_0
(AMINOACYL-TRNA
SYNTHETASE)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 12 LEU A 743
GLY A 858
GLU A 827
VAL A 766
GLY A 602
 None
None
FDP  A   1 (-2.8A)
None
None
 1.31A 5f9zA-3o8oA:
2.4		 5f9zA-3o8oA:
20.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 721
ALA A 603
GLY A 602
THR A 663
LEU A 687
 None
FDP  A   1 ( 3.8A)
None
None
None
 0.88A 5lf7H-3o8oA:
undetectable
5lf7I-3o8oA:
undetectable		 5lf7H-3o8oA:
17.33
5lf7I-3o8oA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_H_6V8H305_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA
(Saccharomyces
cerevisiae) 		5 / 11 ALA B 715
ALA B 596
GLY B 595
THR B 656
LEU B 681
 None
FDP  B   2 (-3.5A)
None
None
None
 0.98A 5lf7H-3o8oB:
undetectable
5lf7I-3o8oB:
undetectable		 5lf7H-3o8oB:
16.60
5lf7I-3o8oB:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA
(Saccharomyces
cerevisiae) 		5 / 11 ALA A 721
ALA A 603
GLY A 602
THR A 663
LEU A 687
 None
FDP  A   1 ( 3.8A)
None
None
None
 0.89A 5lf7V-3o8oA:
undetectable
5lf7W-3o8oA:
undetectable		 5lf7V-3o8oA:
17.33
5lf7W-3o8oA:
13.71
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
5LF7_V_6V8V303_0
(PROTEASOME SUBUNIT
BETA TYPE-3
PROTEASOME SUBUNIT
BETA TYPE-7)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA
(Saccharomyces
cerevisiae) 		5 / 11 ALA B 715
ALA B 596
GLY B 595
THR B 656
LEU B 681
 None
FDP  B   2 (-3.5A)
None
None
None
 0.96A 5lf7V-3o8oB:
undetectable
5lf7W-3o8oB:
undetectable		 5lf7V-3o8oB:
16.60
5lf7W-3o8oB:
15.64
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
6GNF_A_QPSA602_1
(-)		 3o8o 6-PHOSPHOFRUCTOKINAS
E SUBUNIT ALPHA
6-PHOSPHOFRUCTOKINAS
E SUBUNIT BETA
(Saccharomyces
cerevisiae) 		5 / 12 PHE A 762
ASN B 602
GLN B 856
PRO B 597
GLY B 599
 None
None
FDP  B   2 (-3.6A)
None
None
 1.22A 6gnfA-3o8oA:
undetectable		 6gnfA-3o8oA:
21.49