SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'FCB'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_C_CHDC304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		4 / 6 HIS A 121
ASP A 403
TYR A 415
TRP A 122
 FCB  A 501 (-4.0A)
None
FCB  A 501 ( 3.7A)
None
 1.47A 2dysA-3wh7A:
undetectable
2dysC-3wh7A:
undetectable		 2dysA-3wh7A:
21.89
2dysC-3wh7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2DYS_P_CHDP304_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		4 / 6 HIS A 121
ASP A 403
TYR A 415
TRP A 122
 FCB  A 501 (-4.0A)
None
FCB  A 501 ( 3.7A)
None
 1.47A 2dysN-3wh7A:
undetectable
2dysP-3wh7A:
undetectable		 2dysN-3wh7A:
21.89
2dysP-3wh7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIK_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		4 / 7 HIS A 121
ASP A 403
TYR A 415
TRP A 122
 FCB  A 501 (-4.0A)
None
FCB  A 501 ( 3.7A)
None
 1.49A 2eikA-3wh7A:
undetectable
2eikC-3wh7A:
undetectable		 2eikA-3wh7A:
21.89
2eikC-3wh7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIM_A_CHDA525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		4 / 6 HIS A 121
ASP A 403
TYR A 415
TRP A 122
 FCB  A 501 (-4.0A)
None
FCB  A 501 ( 3.7A)
None
 1.42A 2eimA-3wh7A:
undetectable
2eimC-3wh7A:
undetectable		 2eimA-3wh7A:
21.89
2eimC-3wh7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2EIN_C_CHDC525_0
(CYTOCHROME C OXIDASE
SUBUNIT 1
CYTOCHROME C OXIDASE
SUBUNIT 3)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		4 / 6 HIS A 121
ASP A 403
TYR A 415
TRP A 122
 FCB  A 501 (-4.0A)
None
FCB  A 501 ( 3.7A)
None
 1.48A 2einA-3wh7A:
undetectable
2einC-3wh7A:
undetectable		 2einA-3wh7A:
21.89
2einC-3wh7A:
20.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2V3D_B_NBVB1504_1
(GLUCOSYLCERAMIDASE)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		5 / 11 ASN A 165
GLU A 166
TYR A 295
GLU A 352
TRP A 399
 FCB  A 501 (-2.9A)
FCB  A 501 (-2.5A)
FCB  A 501 (-4.6A)
FCB  A 501 (-2.7A)
FCB  A 501 (-3.6A)
 0.82A 2v3dB-3wh7A:
15.4		 2v3dB-3wh7A:
22.95
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3V4T_A_ACTA502_0
(UDP-N-ACETYLGLUCOSAM
INE
1-CARBOXYVINYLTRANSF
ERASE)		 4wut ABC TRANSPORTER
SUBSTRATE BINDING
PROTEIN (RIBOSE)
(Agrobacterium
vitis) 		4 / 5 TYR A 159
VAL A 170
SER A 158
GLY A 162
 FCB  A 404 (-4.3A)
None
None
None
 1.27A 3v4tA-4wutA:
undetectable
3v4tD-4wutA:
undetectable		 3v4tA-4wutA:
22.72
3v4tD-4wutA:
22.72
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_B_FOLB301_1
(FOLATE RECEPTOR
ALPHA)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		3 / 3 ASP A 123
TRP A 399
SER A  79
 None
FCB  A 501 (-3.6A)
None
 1.00A 4lrhB-3wh7A:
undetectable		 4lrhB-3wh7A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4LRH_F_FOLF301_1
(FOLATE RECEPTOR
ALPHA)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		3 / 3 ASP A 123
TRP A 399
SER A  79
 None
FCB  A 501 (-3.6A)
None
 1.09A 4lrhF-3wh7A:
undetectable		 4lrhF-3wh7A:
17.24
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4U15_A_0HKA2001_2
(MUSCARINIC
ACETYLCHOLINE
RECEPTOR
M3,LYSOZYME,MUSCARIN
IC ACETYLCHOLINE
RECEPTOR M3)		 3wh7 BETA-GLUCOSIDASE
(metagenomes) 		3 / 3 ASN A 165
PHE A 397
TYR A  76
 FCB  A 501 (-2.9A)
None
None
 0.68A 4u15A-3wh7A:
undetectable		 4u15A-3wh7A:
22.38