SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'F8G'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3B0W_A_DGXA1_2
(NUCLEAR RECEPTOR
ROR-GAMMA)		 6co9 PROBABLE
COA-TRANSFERASE
ALPHA SUBUNIT
(Rhodococcus
jostii) 		3 / 3 TRP A  29
VAL A 132
ARG A 134
 F8G  B 302 ( 4.6A)
None
None
 0.85A 3b0wA-6co9A:
undetectable		 3b0wA-6co9A:
13.58
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3IV6_B_SAMB301_0
(PUTATIVE
ZN-DEPENDENT ALCOHOL
DEHYDROGENASE)		 6co9 PROBABLE
COA-TRANSFERASE
ALPHA SUBUNIT
PROBABLE
COA-TRANSFERASE BETA
SUBUNIT
(Rhodococcus
jostii;
Rhodococcus
jostii) 		5 / 12 PHE B 123
GLY A  30
SER A  78
PHE B  80
ASP A 187
 None
None
None
F8G  B 302 ( 4.4A)
None
 1.31A 3iv6B-6co9B:
2.4		 3iv6B-6co9B:
undetectable