SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'F6J'

List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)

Filter list by:

	DrReposER ID / Desc.	Hit PDBID	Hit Macromolecule	Res. Matches	Interface	HETATM	RMSD	Dali Z-score	Seq. Identity (%)
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1FMO_E_ADNE351_1 (CAMP-DEPENDENT PROTEIN KINASE)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 249 VAL A 270 ASN A 317 LEU A 319 ASP A 330	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) None F6J A 501 (-4.0A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.51A	1fmoE-6cmjA: 24.0	1fmoE-6cmjA: 14.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1OPJ_B_STIB4_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	VAL A 179 ALA A 192 GLU A 236 VAL A 249 GLY A 273 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None F6J A 501 ( 3.7A) F6J A 501 ( 4.0A)	0.90A	1opjB-6cmjA: 22.0	1opjB-6cmjA: 14.75
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	1XBB_A_STIA1_1 (TYROSINE-PROTEIN KINASE SYK)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 9	VAL A 179 ALA A 192 GLY A 273 PRO A 274 LEU A 319	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.6A) F6J A 501 (-4.5A)	0.47A	1xbbA-6cmjA: 25.1	1xbbA-6cmjA: 14.17
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2EUF_B_LQQB401_1 (CELL DIVISION PROTEIN KINASE 6)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	10 / 12	ILE A 171 VAL A 179 LYS A 194 VAL A 249 PHE A 267 VAL A 270 ASN A 317 LEU A 319 ALA A 329 ASP A 330	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-2.9A) None F6J A 501 (-3.7A) F6J A 501 (-4.0A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A) F6J A 501 (-3.8A)	0.76A	2eufB-6cmjA: 27.4	2eufB-6cmjA: 11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_A_MIXA539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 270 ASP A 312 LYS A 314 ASN A 317 ASP A 330	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-4.0A) None None F6J A 501 ( 4.7A) F6J A 501 (-3.8A)	0.58A	2fumA-6cmjA: 20.5	2fumA-6cmjA: 13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2FUM_B_MIXB1539_1 (PROBABLE SERINE/THREONINE-PRO TEIN KINASE PKNB)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 270 LYS A 314 ASN A 317 ASP A 330	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-4.0A) None F6J A 501 ( 4.7A) F6J A 501 (-3.8A)	0.68A	2fumB-6cmjA: 28.2	2fumB-6cmjA: 13.38
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2HYY_B_STIB600_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	VAL A 179 ALA A 192 GLU A 236 GLY A 273 LEU A 319 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 4.7A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.82A	2hyyB-6cmjA: 22.1	2hyyB-6cmjA: 14.50
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2WLK_B_SPMB1302_1 (ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 4	ALA A 182 TYR A 183 ALA A 192 TYR A 190	None None F6J A 501 (-3.4A) None	1.28A	2wlkA-6cmjA: undetectable 2wlkB-6cmjA: undetectable	2wlkA-6cmjA: 10.96 2wlkB-6cmjA: 10.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_A_B49A1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 ASP A 330	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-3.7A) F6J A 501 ( 4.4A) F6J A 501 (-3.8A)	0.67A	2y7jA-6cmjA: 31.1	2y7jA-6cmjA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_A_B49A1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-3.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.47A	2y7jA-6cmjA: 31.1	2y7jA-6cmjA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_B_B49B1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 10	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 ASP A 330	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-3.7A) F6J A 501 ( 4.4A) F6J A 501 (-3.8A)	0.69A	2y7jB-6cmjA: 30.9	2y7jB-6cmjA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_B_B49B1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 10	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-3.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.55A	2y7jB-6cmjA: 30.9	2y7jB-6cmjA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_C_B49C1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 10	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-3.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.54A	2y7jC-6cmjA: 30.9	2y7jC-6cmjA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2Y7J_D_B49D1294_1 (PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS/LIVER ISOFORM)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 10	ILE A 171 VAL A 179 ALA A 192 PHE A 267 LEU A 269 GLY A 273 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-3.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.58A	2y7jD-6cmjA: 30.7	2y7jD-6cmjA: 13.85
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	2YGQ_A_PCFA1275_0 (WNT INHIBITORY FACTOR 1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	LEU A 319 ILE A 328 LEU A 303 ILE A 239 VAL A 179	F6J A 501 (-4.5A) None None None F6J A 501 (-4.6A)	1.07A	2ygqA-6cmjA: undetectable	2ygqA-6cmjA: undetectable
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3BBT_B_FMMB91_1 (RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	VAL A 179 ALA A 192 LEU A 251 LEU A 269 GLY A 273 LEU A 319	F6J A 501 (-4.6A) F6J A 501 (-3.4A) None F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.64A	3bbtB-6cmjA: 21.8	3bbtB-6cmjA: 10.67
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK3_A_0LIA1_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 VAL A 249 HIS A 310 LEU A 319 ALA A 329	F6J A 501 (-3.4A) None None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.48A	3ik3A-6cmjA: 22.2	3ik3A-6cmjA: 14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3IK3_B_0LIB2_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 VAL A 249 HIS A 310 LEU A 319 ALA A 329	F6J A 501 (-3.4A) None None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.48A	3ik3B-6cmjA: 22.0	3ik3B-6cmjA: 14.18
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3MIY_A_B49A1_1 (TYROSINE-PROTEIN KINASE ITK/TSK)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 11	ILE A 171 ALA A 192 VAL A 249 PHE A 267 GLY A 273 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-3.4A) None F6J A 501 (-3.7A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.77A	3miyA-6cmjA: 22.9	3miyA-6cmjA: 16.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OG7_A_032A1_1 (AKAP9-BRAF FUSION PROTEIN)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	ILE A 171 VAL A 179 ALA A 192 LYS A 194 LEU A 240 PHE A 331	F6J A 501 (-4.3A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) None None	1.18A	3og7A-6cmjA: 17.9	3og7A-6cmjA: 16.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OHT_B_1N1B1000_1 (P38A)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	GLY A 172 VAL A 179 ALA A 192 LYS A 194 LEU A 240 GLY A 273	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) None F6J A 501 ( 3.7A)	0.75A	3ohtB-6cmjA: 6.5	3ohtB-6cmjA: 11.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3OXZ_A_0LIA1_1 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	ALA A 192 GLU A 236 VAL A 249 GLY A 273 HIS A 310 ALA A 329	F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None F6J A 501 ( 3.7A) None F6J A 501 ( 4.0A)	0.81A	3oxzA-6cmjA: 3.7	3oxzA-6cmjA: 14.55
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3RGF_A_BAXA465_1 (CYCLIN-DEPENDENT KINASE 8)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 GLU A 236 LEU A 240 PHE A 267 LEU A 303 HIS A 310 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None F6J A 501 (-3.7A) None None F6J A 501 ( 4.0A)	0.81A	3rgfA-6cmjA: 7.6	3rgfA-6cmjA: 15.12
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3TI1_A_B49A299_1 (CYCLIN-DEPENDENT KINASE 2)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 9	ILE A 171 ALA A 192 VAL A 249 PHE A 267 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-3.4A) None F6J A 501 (-3.7A) F6J A 501 (-4.5A)	0.64A	3ti1A-6cmjA: 23.7	3ti1A-6cmjA: 17.19
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WZD_A_LEVA1201_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 5	LYS A 194 ILE A 239 VAL A 249 LEU A 319 ASP A 330	F6J A 501 (-2.9A) None None F6J A 501 (-4.5A) F6J A 501 (-3.8A)	1.09A	3wzdA-6cmjA: 22.4	3wzdA-6cmjA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3WZE_A_BAXA1201_2 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 8	VAL A 248 VAL A 249 LEU A 319 ILE A 328	None None F6J A 501 (-4.5A) None	0.51A	3wzeA-6cmjA: 22.3	3wzeA-6cmjA: 14.96
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	3ZBF_A_VGHA3000_1 (PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 LEU A 269 GLY A 273 LEU A 319 ASP A 330	F6J A 501 (-3.4A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.50A	3zbfA-6cmjA: 24.2	3zbfA-6cmjA: 16.56
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4ASD_A_BAXA1500_1 (VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 LEU A 240 GLY A 273 LEU A 303 HIS A 310	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) None F6J A 501 ( 3.7A) None None	0.83A	4asdA-6cmjA: 22.0	4asdA-6cmjA: 15.59
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_A_0LIA1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ALA A 192 LYS A 194 GLU A 236 LEU A 240 HIS A 310 LEU A 319 ALA A 329	F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) None None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.97A	4c8bA-6cmjA: 23.0	4c8bA-6cmjA: 15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4C8B_B_0LIB1000_1 (RECEPTOR-INTERACTING SERINE/THREONINE-PRO TEIN KINASE 2)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ALA A 192 LYS A 194 GLU A 236 LEU A 240 HIS A 310 LEU A 319 ALA A 329	F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) None None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.93A	4c8bB-6cmjA: 16.4	4c8bB-6cmjA: 15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4CSV_A_STIA1265_1 (SRC-ABL TYROSINE KINASE ANCESTOR)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 GLU A 236 ILE A 239 VAL A 249 LEU A 319 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.87A	4csvA-6cmjA: 23.2	4csvA-6cmjA: 14.94
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4I41_A_MIXA500_1 (SERINE/THREONINE-PRO TEIN KINASE PIM-1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 ASP A 312 LYS A 314 ASN A 317 LEU A 319 ASP A 330	F6J A 501 (-4.6A) F6J A 501 (-3.4A) None None F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.67A	4i41A-6cmjA: 22.4	4i41A-6cmjA: 13.45
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4O0W_A_ADNA501_1 (AURORA KINASE A)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 6	GLY A 172 VAL A 179 ALA A 192 LEU A 319	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-4.5A)	0.25A	4o0wA-6cmjA: 24.1	4o0wA-6cmjA: 11.93
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_A_ADNA401_1 (CYCLIN-DEPENDENT KINASE 9)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 8	GLY A 174 VAL A 179 ALA A 192 ASN A 317 LEU A 319 ASP A 330	F6J A 501 (-3.5A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.77A	4ogrA-6cmjA: 27.5	4ogrA-6cmjA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_A_ADNA401_1 (CYCLIN-DEPENDENT KINASE 9)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 8	ILE A 171 GLY A 174 VAL A 179 ALA A 192 ASN A 317 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-3.5A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A)	0.78A	4ogrA-6cmjA: 27.5	4ogrA-6cmjA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OGR_I_ADNI401_1 (CYCLIN-DEPENDENT KINASE 9)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 9	ILE A 171 GLY A 174 VAL A 179 ALA A 192 ASN A 317 LEU A 319 ASP A 330	F6J A 501 (-4.3A) F6J A 501 (-3.5A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.73A	4ogrI-6cmjA: 27.5	4ogrI-6cmjA: 14.92
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OR0_A_NPSA602_1 (SERUM ALBUMIN)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 9	PHE A 267 ALA A 192 ALA A 182 LEU A 162 VAL A 252	F6J A 501 (-3.7A) F6J A 501 (-3.4A) None None None	1.38A	4or0A-6cmjA: 2.4	4or0A-6cmjA: 9.20
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTI_A_MI1A1001_1 (SERINE/THREONINE-PRO TEIN KINASE N1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	GLY A 172 GLY A 177 VAL A 179 ALA A 192 VAL A 249 LEU A 319 ALA A 329	F6J A 501 ( 3.9A) FMT A 503 (-3.6A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.51A	4otiA-6cmjA: 24.3	4otiA-6cmjA: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4OTI_A_MI1A1001_1 (SERINE/THREONINE-PRO TEIN KINASE N1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	GLY A 172 VAL A 179 ALA A 192 LYS A 194 VAL A 249 LEU A 319 ALA A 329	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.49A	4otiA-6cmjA: 24.3	4otiA-6cmjA: 14.16
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4QMN_A_DB8A401_1 (SERINE/THREONINE-PRO TEIN KINASE 24)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ILE A 171 ALA A 192 LYS A 194 GLU A 236 LEU A 319 ALA A 329 ASP A 330	F6J A 501 (-4.3A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A) F6J A 501 (-3.8A)	0.85A	4qmnA-6cmjA: 21.4	4qmnA-6cmjA: 14.84
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4RZ7_A_1E8A901_1 (CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 10	ILE A 171 ALA A 192 LYS A 194 LEU A 269 VAL A 270 LEU A 319	F6J A 501 (-4.3A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.4A) F6J A 501 (-4.0A) F6J A 501 (-4.5A)	0.69A	4rz7A-6cmjA: 28.7	4rz7A-6cmjA: 7.10
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_A_AXIA601_1 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 LYS A 194 GLY A 273 ASN A 317 LEU A 319 ALA A 329 ASP A 330	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 3.7A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A) F6J A 501 (-3.8A)	0.63A	4twpA-6cmjA: 24.7	4twpA-6cmjA: 14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4TWP_B_AXIB601_1 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 LYS A 194 GLY A 273 ASN A 317 LEU A 319 ALA A 329 ASP A 330	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 3.7A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A) F6J A 501 (-3.8A)	0.67A	4twpB-6cmjA: 25.2	4twpB-6cmjA: 14.66
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4UXQ_A_0LIA1752_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 4)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 LEU A 303 HIS A 310 LEU A 319 ALA A 329	F6J A 501 (-3.4A) None None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.53A	4uxqA-6cmjA: 22.3	4uxqA-6cmjA: 15.60
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V01_A_0LIA1776_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 GLU A 236 LEU A 303 HIS A 310 ALA A 329	F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None None F6J A 501 ( 4.0A)	0.84A	4v01A-6cmjA: 21.9	4v01A-6cmjA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V01_B_0LIB1770_1 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 GLU A 236 LEU A 303 HIS A 310 ALA A 329	F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None None F6J A 501 ( 4.0A)	0.81A	4v01B-6cmjA: 22.2	4v01B-6cmjA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4V04_B_0LIB1771_2 (FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 GLU A 236 LEU A 303 HIS A 310 ALA A 329	F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None None F6J A 501 ( 4.0A)	0.86A	4v04B-6cmjA: 21.9	4v04B-6cmjA: 18.26
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	4WA9_B_AXIB9000_1 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 GLY A 273 ASN A 317 LEU A 319 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 3.7A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.73A	4wa9B-6cmjA: 24.4	4wa9B-6cmjA: 14.49
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5L2I_A_LQQA900_1 (CYCLIN-DEPENDENT KINASE 6)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	GLY A 172 VAL A 179 ALA A 192 VAL A 249 PHE A 267 LEU A 319 ALA A 329 ASP A 330	F6J A 501 ( 3.9A) F6J A 501 (-4.6A) F6J A 501 (-3.4A) None F6J A 501 (-3.7A) F6J A 501 (-4.5A) F6J A 501 ( 4.0A) F6J A 501 (-3.8A)	0.81A	5l2iA-6cmjA: 22.4	5l2iA-6cmjA: 11.76
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5MO4_A_NILA601_2 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	5 / 12	ALA A 192 VAL A 249 HIS A 310 LEU A 319 ALA A 329	F6J A 501 (-3.4A) None None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.56A	5mo4A-6cmjA: 19.0	5mo4A-6cmjA: 10.83
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5OWR_A_1N1A401_1 (SERINE/THREONINE-PRO TEIN KINASE 10)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 8	ALA A 192 GLU A 236 LEU A 319 ASP A 330	F6J A 501 (-3.4A) F6J A 501 ( 4.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.44A	5owrA-6cmjA: 23.2	5owrA-6cmjA: 10.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5TE0_A_XINA401_1 (AP2-ASSOCIATED PROTEIN KINASE 1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	6 / 12	LEU A 181 ALA A 192 GLU A 236 VAL A 249 GLY A 273 LEU A 319	None F6J A 501 (-3.4A) F6J A 501 ( 4.7A) None F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.65A	5te0A-6cmjA: 27.1	5te0A-6cmjA: 10.62
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5VCY_A_DB8A401_2 (MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 4	VAL A 249 LEU A 269 ASN A 317 ASP A 330	None F6J A 501 ( 4.4A) F6J A 501 ( 4.7A) F6J A 501 (-3.8A)	0.85A	5vcyA-6cmjA: 24.2	5vcyA-6cmjA: 14.70
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 LEU A 269 GLY A 273 LEU A 319	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.62A	5y7zA-6cmjA: 25.3	5y7zA-6cmjA: 15.15
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 LEU A 269 GLY A 273 LEU A 319	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A)	0.62A	5y7zA-6cmjA: 25.3	5y7zA-6cmjA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y7Z_B_IREB401_0 (CYCLIN-G-ASSOCIATED KINASE)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	ALA A 192 LYS A 194 GLU A 236 LEU A 269 GLY A 273 LEU A 319 ASP A 330	F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.67A	5y7zB-6cmjA: 25.3	5y7zB-6cmjA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5Y80_A_IREA401_0 (CYCLIN-G-ASSOCIATED KINASE)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	8 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 LEU A 269 GLY A 273 LEU A 319 ASP A 330	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) F6J A 501 ( 4.4A) F6J A 501 ( 3.7A) F6J A 501 (-4.5A) F6J A 501 (-3.8A)	0.65A	5y80A-6cmjA: 24.6	5y80A-6cmjA: 25.00
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YF9_B_NIOB401_1 (CASEIN KINASE II SUBUNIT ALPHA')	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 7	VAL A 179 LYS A 194 PHE A 267 ASP A 330	F6J A 501 (-4.6A) F6J A 501 (-2.9A) F6J A 501 (-3.7A) F6J A 501 (-3.8A)	0.87A	5yf9B-6cmjA: 24.5	5yf9B-6cmjA: 29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	5YWM_X_NIOX403_0 (CASEIN KINASE II SUBUNIT ALPHA')	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	4 / 7	VAL A 179 LYS A 194 PHE A 267 ASP A 330	F6J A 501 (-4.6A) F6J A 501 (-2.9A) F6J A 501 (-3.7A) F6J A 501 (-3.8A)	0.61A	5ywmX-6cmjA: 25.1	5ywmX-6cmjA: 29.41
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_A_STIA604_0 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 VAL A 249 LEU A 319 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.89A	6hd4A-6cmjA: 22.0	6hd4A-6cmjA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD4_B_STIB602_0 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 VAL A 249 LEU A 319 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.88A	6hd4B-6cmjA: 21.8	6hd4B-6cmjA: 19.28
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.	6HD6_A_STIA603_0 (TYROSINE-PROTEIN KINASE ABL1)	6cmj	CALCIUM/CALMODULIN-D EPENDENT PROTEIN KINASE KINASE 2 (Homo sapiens)	7 / 12	VAL A 179 ALA A 192 LYS A 194 GLU A 236 VAL A 249 LEU A 319 ALA A 329	F6J A 501 (-4.6A) F6J A 501 (-3.4A) F6J A 501 (-2.9A) F6J A 501 ( 4.7A) None F6J A 501 (-4.5A) F6J A 501 ( 4.0A)	0.90A	6hd6A-6cmjA: 21.9	6hd6A-6cmjA: 19.28

[["DrReposER ID","Desc.","Hit PDB","Hit molecule","Hit organism","Res. no.","Interface","HETATM","RMSD","Z-score","Seq ID"],["1FMO_E_ADNE351_1","CAMP-DEPENDENT PROTEIN KINASE","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"GLY A 172;VAL A 179;ALA A 192;VAL A 249;VAL A 270;ASN A 317;LEU A 319;ASP A 330","F6J A 501 ( 3.9A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);None;F6J A 501 (-4.0A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.51A","1fmoE-6cmjA:24.0",null],["1OPJ_B_STIB4_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;GLU A 236;VAL A 249;GLY A 273;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;F6J A 501 ( 3.7A);F6J A 501 ( 4.0A)","0.90A","1opjB-6cmjA:22.0","1fmoE-6cmjA:14.85"],["1XBB_A_STIA1_1","TYROSINE-PROTEIN KINASE SYK","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"VAL A 179;ALA A 192;GLY A 273;PRO A 274;LEU A 319","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.6A);F6J A 501 (-4.5A)","0.47A","1xbbA-6cmjA:25.1","1opjB-6cmjA:14.75"],["2EUF_B_LQQB401_1","CELL DIVISION PROTEIN KINASE 6","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",10,"ILE A 171;VAL A 179;LYS A 194;VAL A 249;PHE A 267;VAL A 270;ASN A 317;LEU A 319;ALA A 329;ASP A 330","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-2.9A);None;F6J A 501 (-3.7A);F6J A 501 (-4.0A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 ( 4.0A);F6J A 501 (-3.8A)","0.76A","2eufB-6cmjA:27.4","1xbbA-6cmjA:14.17"],["2FUM_A_MIXA539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"GLY A 172;VAL A 179;ALA A 192;VAL A 270;ASP A 312;LYS A 314;ASN A 317;ASP A 330","F6J A 501 ( 3.9A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-4.0A);None;None;F6J A 501 ( 4.7A);F6J A 501 (-3.8A)","0.58A","2fumA-6cmjA:20.5","2eufB-6cmjA:11.76"],["2FUM_B_MIXB1539_1","PROBABLE SERINE\/THREONINE-PROTEIN KINASE PKNB","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"GLY A 172;VAL A 179;ALA A 192;VAL A 270;LYS A 314;ASN A 317;ASP A 330","F6J A 501 ( 3.9A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-4.0A);None;F6J A 501 ( 4.7A);F6J A 501 (-3.8A)","0.68A","2fumB-6cmjA:28.2","2fumA-6cmjA:13.38"],["2HYY_B_STIB600_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;GLU A 236;GLY A 273;LEU A 319;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 4.7A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.82A","2hyyB-6cmjA:22.1","2fumB-6cmjA:13.38"],["2WLK_B_SPMB1302_1","ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10;ATP-SENSITIVE INWARD RECTIFIER POTASSIUM CHANNEL 10","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"ALA A 182;TYR A 183;ALA A 192;TYR A 190","None;None;F6J A 501 (-3.4A);None","1.28A","2wlkA-6cmjA:undetectable;2wlkB-6cmjA:undetectable","2hyyB-6cmjA:14.50"],["2Y7J_A_B49A1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;ASP A 330","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-3.7A);F6J A 501 ( 4.4A);F6J A 501 (-3.8A)","0.67A","2y7jA-6cmjA:31.1","2wlkA-6cmjA:10.96;2wlkB-6cmjA:10.96"],["2Y7J_A_B49A1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-3.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.47A","2y7jA-6cmjA:31.1","2y7jA-6cmjA:13.85"],["2Y7J_B_B49B1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;ASP A 330","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-3.7A);F6J A 501 ( 4.4A);F6J A 501 (-3.8A)","0.69A","2y7jB-6cmjA:30.9","2y7jA-6cmjA:13.85"],["2Y7J_B_B49B1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-3.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.55A","2y7jB-6cmjA:30.9","2y7jB-6cmjA:13.85"],["2Y7J_C_B49C1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-3.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.54A","2y7jC-6cmjA:30.9","2y7jB-6cmjA:13.85"],["2Y7J_D_B49D1294_1","PHOSPHORYLASE B KINASE GAMMA CATALYTIC CHAIN, TESTIS\/LIVER ISOFORM","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;VAL A 179;ALA A 192;PHE A 267;LEU A 269;GLY A 273;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-3.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.58A","2y7jD-6cmjA:30.7","2y7jC-6cmjA:13.85"],["2YGQ_A_PCFA1275_0","WNT INHIBITORY FACTOR 1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"LEU A 319;ILE A 328;LEU A 303;ILE A 239;VAL A 179","F6J A 501 (-4.5A);None;None;None;F6J A 501 (-4.6A)","1.07A","2ygqA-6cmjA:undetectable","2y7jD-6cmjA:13.85"],["3BBT_B_FMMB91_1","RECEPTOR TYROSINE-PROTEIN KINASE ERBB-4","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"VAL A 179;ALA A 192;LEU A 251;LEU A 269;GLY A 273;LEU A 319","F6J A 501 (-4.6A);F6J A 501 (-3.4A);None;F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.64A","3bbtB-6cmjA:21.8","2ygqA-6cmjA:undetectable"],["3IK3_A_0LIA1_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;VAL A 249;HIS A 310;LEU A 319;ALA A 329","F6J A 501 (-3.4A);None;None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.48A","3ik3A-6cmjA:22.2","3bbtB-6cmjA:10.67"],["3IK3_B_0LIB2_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;VAL A 249;HIS A 310;LEU A 319;ALA A 329","F6J A 501 (-3.4A);None;None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.48A","3ik3B-6cmjA:22.0","3ik3A-6cmjA:14.18"],["3MIY_A_B49A1_1","TYROSINE-PROTEIN KINASE ITK\/TSK","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;ALA A 192;VAL A 249;PHE A 267;GLY A 273;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-3.4A);None;F6J A 501 (-3.7A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.77A","3miyA-6cmjA:22.9","3ik3B-6cmjA:14.18"],["3OG7_A_032A1_1","AKAP9-BRAF FUSION PROTEIN","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;VAL A 179;ALA A 192;LYS A 194;LEU A 240;PHE A 331","F6J A 501 (-4.3A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);None;None","1.18A","3og7A-6cmjA:17.9","3miyA-6cmjA:16.59"],["3OHT_B_1N1B1000_1","P38A","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"GLY A 172;VAL A 179;ALA A 192;LYS A 194;LEU A 240;GLY A 273","F6J A 501 ( 3.9A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);None;F6J A 501 ( 3.7A)","0.75A","3ohtB-6cmjA:6.5","3og7A-6cmjA:16.49"],["3OXZ_A_0LIA1_1","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ALA A 192;GLU A 236;VAL A 249;GLY A 273;HIS A 310;ALA A 329","F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;F6J A 501 ( 3.7A);None;F6J A 501 ( 4.0A)","0.81A","3oxzA-6cmjA:3.7","3ohtB-6cmjA:11.92"],["3RGF_A_BAXA465_1","CYCLIN-DEPENDENT KINASE 8","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"VAL A 179;ALA A 192;GLU A 236;LEU A 240;PHE A 267;LEU A 303;HIS A 310;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;F6J A 501 (-3.7A);None;None;F6J A 501 ( 4.0A)","0.81A","3rgfA-6cmjA:7.6","3oxzA-6cmjA:14.55"],["3TI1_A_B49A299_1","CYCLIN-DEPENDENT KINASE 2","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ILE A 171;ALA A 192;VAL A 249;PHE A 267;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-3.4A);None;F6J A 501 (-3.7A);F6J A 501 (-4.5A)","0.64A","3ti1A-6cmjA:23.7","3rgfA-6cmjA:15.12"],["3WZD_A_LEVA1201_2","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"LYS A 194;ILE A 239;VAL A 249;LEU A 319;ASP A 330","F6J A 501 (-2.9A);None;None;F6J A 501 (-4.5A);F6J A 501 (-3.8A)","1.09A","3wzdA-6cmjA:22.4","3ti1A-6cmjA:17.19"],["3WZE_A_BAXA1201_2","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"VAL A 248;VAL A 249;LEU A 319;ILE A 328","None;None;F6J A 501 (-4.5A);None","0.51A","3wzeA-6cmjA:22.3","3wzdA-6cmjA:14.96"],["3ZBF_A_VGHA3000_1","PROTO-ONCOGENE TYROSINE-PROTEIN KINASE ROS","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;LEU A 269;GLY A 273;LEU A 319;ASP A 330","F6J A 501 (-3.4A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.50A","3zbfA-6cmjA:24.2","3wzeA-6cmjA:14.96"],["4ASD_A_BAXA1500_1","VASCULAR ENDOTHELIAL GROWTH FACTOR RECEPTOR 2","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;LEU A 240;GLY A 273;LEU A 303;HIS A 310","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);None;F6J A 501 ( 3.7A);None;None","0.83A","4asdA-6cmjA:22.0","3zbfA-6cmjA:16.56"],["4C8B_A_0LIA1000_1","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ALA A 192;LYS A 194;GLU A 236;LEU A 240;HIS A 310;LEU A 319;ALA A 329","F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);None;None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.97A","4c8bA-6cmjA:23.0","4asdA-6cmjA:15.59"],["4C8B_B_0LIB1000_1","RECEPTOR-INTERACTING SERINE\/THREONINE-PROTEIN KINASE 2","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ALA A 192;LYS A 194;GLU A 236;LEU A 240;HIS A 310;LEU A 319;ALA A 329","F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);None;None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.93A","4c8bB-6cmjA:16.4","4c8bA-6cmjA:15.60"],["4CSV_A_STIA1265_1","SRC-ABL TYROSINE KINASE ANCESTOR","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;GLU A 236;ILE A 239;VAL A 249;LEU A 319;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.87A","4csvA-6cmjA:23.2","4c8bB-6cmjA:15.60"],["4I41_A_MIXA500_1","SERINE\/THREONINE-PROTEIN KINASE PIM-1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;ASP A 312;LYS A 314;ASN A 317;LEU A 319;ASP A 330","F6J A 501 (-4.6A);F6J A 501 (-3.4A);None;None;F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.67A","4i41A-6cmjA:22.4","4csvA-6cmjA:14.94"],["4O0W_A_ADNA501_1","AURORA KINASE A","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"GLY A 172;VAL A 179;ALA A 192;LEU A 319","F6J A 501 ( 3.9A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-4.5A)","0.25A","4o0wA-6cmjA:24.1","4i41A-6cmjA:13.45"],["4OGR_A_ADNA401_1","CYCLIN-DEPENDENT KINASE 9","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"GLY A 174;VAL A 179;ALA A 192;ASN A 317;LEU A 319;ASP A 330","F6J A 501 (-3.5A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.77A","4ogrA-6cmjA:27.5","4o0wA-6cmjA:11.93"],["4OGR_A_ADNA401_1","CYCLIN-DEPENDENT KINASE 9","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;GLY A 174;VAL A 179;ALA A 192;ASN A 317;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-3.5A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A)","0.78A","4ogrA-6cmjA:27.5","4ogrA-6cmjA:14.92"],["4OGR_I_ADNI401_1","CYCLIN-DEPENDENT KINASE 9","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;GLY A 174;VAL A 179;ALA A 192;ASN A 317;LEU A 319;ASP A 330","F6J A 501 (-4.3A);F6J A 501 (-3.5A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.73A","4ogrI-6cmjA:27.5","4ogrA-6cmjA:14.92"],["4OR0_A_NPSA602_1","SERUM ALBUMIN","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"PHE A 267;ALA A 192;ALA A 182;LEU A 162;VAL A 252","F6J A 501 (-3.7A);F6J A 501 (-3.4A);None;None;None","1.38A","4or0A-6cmjA:2.4","4ogrI-6cmjA:14.92"],["4OTI_A_MI1A1001_1","SERINE\/THREONINE-PROTEIN KINASE N1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"GLY A 172;GLY A 177;VAL A 179;ALA A 192;VAL A 249;LEU A 319;ALA A 329","F6J A 501 ( 3.9A);FMT A 503 (-3.6A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.51A","4otiA-6cmjA:24.3","4or0A-6cmjA:9.20"],["4OTI_A_MI1A1001_1","SERINE\/THREONINE-PROTEIN KINASE N1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"GLY A 172;VAL A 179;ALA A 192;LYS A 194;VAL A 249;LEU A 319;ALA A 329","F6J A 501 ( 3.9A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.49A","4otiA-6cmjA:24.3","4otiA-6cmjA:14.16"],["4QMN_A_DB8A401_1","SERINE\/THREONINE-PROTEIN KINASE 24","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ILE A 171;ALA A 192;LYS A 194;GLU A 236;LEU A 319;ALA A 329;ASP A 330","F6J A 501 (-4.3A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 ( 4.0A);F6J A 501 (-3.8A)","0.85A","4qmnA-6cmjA:21.4","4otiA-6cmjA:14.16"],["4RZ7_A_1E8A901_1","CGMP-DEPENDENT PROTEIN KINASE, PUTATIVE","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"ILE A 171;ALA A 192;LYS A 194;LEU A 269;VAL A 270;LEU A 319","F6J A 501 (-4.3A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.4A);F6J A 501 (-4.0A);F6J A 501 (-4.5A)","0.69A","4rz7A-6cmjA:28.7","4qmnA-6cmjA:14.84"],["4TWP_A_AXIA601_1","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"VAL A 179;ALA A 192;LYS A 194;GLY A 273;ASN A 317;LEU A 319;ALA A 329;ASP A 330","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 3.7A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 ( 4.0A);F6J A 501 (-3.8A)","0.63A","4twpA-6cmjA:24.7","4rz7A-6cmjA:7.10"],["4TWP_B_AXIB601_1","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"VAL A 179;ALA A 192;LYS A 194;GLY A 273;ASN A 317;LEU A 319;ALA A 329;ASP A 330","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 3.7A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 ( 4.0A);F6J A 501 (-3.8A)","0.67A","4twpB-6cmjA:25.2","4twpA-6cmjA:14.66"],["4UXQ_A_0LIA1752_1","FIBROBLAST GROWTH FACTOR RECEPTOR 4","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;LEU A 303;HIS A 310;LEU A 319;ALA A 329","F6J A 501 (-3.4A);None;None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.53A","4uxqA-6cmjA:22.3","4twpB-6cmjA:14.66"],["4V01_A_0LIA1776_1","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;GLU A 236;LEU A 303;HIS A 310;ALA A 329","F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;None;F6J A 501 ( 4.0A)","0.84A","4v01A-6cmjA:21.9","4uxqA-6cmjA:15.60"],["4V01_B_0LIB1770_1","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;GLU A 236;LEU A 303;HIS A 310;ALA A 329","F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;None;F6J A 501 ( 4.0A)","0.81A","4v01B-6cmjA:22.2","4v01A-6cmjA:18.26"],["4V04_B_0LIB1771_2","FIBROBLAST GROWTH FACTOR RECEPTOR 1 (FMS-RELATED TYROSINE KINASE 2, PFEIFFER SYNDROME), ISOFORM CRA_B","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;GLU A 236;LEU A 303;HIS A 310;ALA A 329","F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;None;F6J A 501 ( 4.0A)","0.86A","4v04B-6cmjA:21.9","4v01B-6cmjA:18.26"],["4WA9_B_AXIB9000_1","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LYS A 194;GLY A 273;ASN A 317;LEU A 319;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 3.7A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.73A","4wa9B-6cmjA:24.4","4v04B-6cmjA:18.26"],["5L2I_A_LQQA900_1","CYCLIN-DEPENDENT KINASE 6","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"GLY A 172;VAL A 179;ALA A 192;VAL A 249;PHE A 267;LEU A 319;ALA A 329;ASP A 330","F6J A 501 ( 3.9A);F6J A 501 (-4.6A);F6J A 501 (-3.4A);None;F6J A 501 (-3.7A);F6J A 501 (-4.5A);F6J A 501 ( 4.0A);F6J A 501 (-3.8A)","0.81A","5l2iA-6cmjA:22.4","4wa9B-6cmjA:14.49"],["5MO4_A_NILA601_2","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",5,"ALA A 192;VAL A 249;HIS A 310;LEU A 319;ALA A 329","F6J A 501 (-3.4A);None;None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.56A","5mo4A-6cmjA:19.0","5l2iA-6cmjA:11.76"],["5OWR_A_1N1A401_1","SERINE\/THREONINE-PROTEIN KINASE 10","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"ALA A 192;GLU A 236;LEU A 319;ASP A 330","F6J A 501 (-3.4A);F6J A 501 ( 4.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.44A","5owrA-6cmjA:23.2","5mo4A-6cmjA:10.83"],["5TE0_A_XINA401_1","AP2-ASSOCIATED PROTEIN KINASE 1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",6,"LEU A 181;ALA A 192;GLU A 236;VAL A 249;GLY A 273;LEU A 319","None;F6J A 501 (-3.4A);F6J A 501 ( 4.7A);None;F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.65A","5te0A-6cmjA:27.1","5owrA-6cmjA:10.70"],["5VCY_A_DB8A401_2","MEMBRANE-ASSOCIATED TYROSINE- AND THREONINE-SPECIFIC CDC2-INHIBITORY KINASE","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"VAL A 249;LEU A 269;ASN A 317;ASP A 330","None;F6J A 501 ( 4.4A);F6J A 501 ( 4.7A);F6J A 501 (-3.8A)","0.85A","5vcyA-6cmjA:24.2","5te0A-6cmjA:10.62"],["5Y7Z_A_IREA401_0","CYCLIN-G-ASSOCIATED KINASE","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;LEU A 269;GLY A 273;LEU A 319","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.62A","5y7zA-6cmjA:25.3","5vcyA-6cmjA:14.70"],["5Y7Z_A_IREA401_0","CYCLIN-G-ASSOCIATED KINASE","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;LEU A 269;GLY A 273;LEU A 319","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A)","0.62A","5y7zA-6cmjA:25.3","5y7zA-6cmjA:15.15"],["5Y7Z_B_IREB401_0","CYCLIN-G-ASSOCIATED KINASE","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"ALA A 192;LYS A 194;GLU A 236;LEU A 269;GLY A 273;LEU A 319;ASP A 330","F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.67A","5y7zB-6cmjA:25.3","5y7zA-6cmjA:25.00"],["5Y80_A_IREA401_0","CYCLIN-G-ASSOCIATED KINASE","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",8,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;LEU A 269;GLY A 273;LEU A 319;ASP A 330","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);F6J A 501 ( 4.4A);F6J A 501 ( 3.7A);F6J A 501 (-4.5A);F6J A 501 (-3.8A)","0.65A","5y80A-6cmjA:24.6","5y7zB-6cmjA:25.00"],["5YF9_B_NIOB401_1","CASEIN KINASE II SUBUNIT ALPHA'","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"VAL A 179;LYS A 194;PHE A 267;ASP A 330","F6J A 501 (-4.6A);F6J A 501 (-2.9A);F6J A 501 (-3.7A);F6J A 501 (-3.8A)","0.87A","5yf9B-6cmjA:24.5","5y80A-6cmjA:25.00"],["5YWM_X_NIOX403_0","CASEIN KINASE II SUBUNIT ALPHA'","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",4,"VAL A 179;LYS A 194;PHE A 267;ASP A 330","F6J A 501 (-4.6A);F6J A 501 (-2.9A);F6J A 501 (-3.7A);F6J A 501 (-3.8A)","0.61A","5ywmX-6cmjA:25.1","5yf9B-6cmjA:29.41"],["6HD4_A_STIA604_0","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;VAL A 249;LEU A 319;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.89A","6hd4A-6cmjA:22.0","5ywmX-6cmjA:29.41"],["6HD4_B_STIB602_0","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;VAL A 249;LEU A 319;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.88A","6hd4B-6cmjA:21.8","6hd4A-6cmjA:19.28"],["6HD6_A_STIA603_0","TYROSINE-PROTEIN KINASE ABL1","6cmj","CALCIUM\/CALMODULIN-DEPENDENT PROTEIN KINASE KINASE 2","Homo sapiens",7,"VAL A 179;ALA A 192;LYS A 194;GLU A 236;VAL A 249;LEU A 319;ALA A 329","F6J A 501 (-4.6A);F6J A 501 (-3.4A);F6J A 501 (-2.9A);F6J A 501 ( 4.7A);None;F6J A 501 (-4.5A);F6J A 501 ( 4.0A)","0.90A","6hd6A-6cmjA:21.9","6hd4B-6cmjA:19.28"]]