SIMILAR PATTERN OF AMINO ACIDS MAPPED TO 'F1P'


List of Similar Pattern of Amino Acids

Hit pattern: 3D amino acid arrangements similar to known drug binding site
Query pattern: Residues from known binding site for annotated drug that match the hit pattern

(Click on the DrReposER ID to view details on interfaces and similar patterns of amino acids)
(Click on the view link on the last column to view superposed patterns of amino acids)
Filter list by:
DrReposER ID / Desc. Hit
PDBID		 Hit
Macromolecule		 Res.
Matches		 Interface HETATM RMSD Dali
Z-score		 Seq.
Identity (%)		 View Dock
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
1T9W_A_NFNA6001_1
(ACRIFLAVINE
RESISTANCE PROTEIN B)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 SER A 183
GLY A 181
ARG A 518
 F1P  A 702 ( 4.6A)
F1P  A 702 (-3.6A)
F1P  A 702 ( 4.2A)
 0.67A 1t9wA-4bb9A:
3.0		 1t9wA-4bb9A:
22.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
2NNK_A_ROCA401_2
(PROTEASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 227
VAL A 180
THR A  31
 None
F1P  A 702 (-3.8A)
None
 0.85A 2nnkA-4bb9A:
undetectable		 2nnkA-4bb9A:
11.05
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3FPJ_A_SAMA301_1
(PUTATIVE
UNCHARACTERIZED
PROTEIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 6 GLY A 107
GLU A 153
GLU A 150
GLU A  32
 F1P  A 702 (-4.3A)
F1P  A 702 (-3.3A)
None
None
 1.04A 3fpjA-4bb9A:
3.3		 3fpjA-4bb9A:
20.06
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
3K4V_B_ROCB201_2
(HIV-1 PROTEASE)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		3 / 3 ARG A 227
VAL A 180
THR A  31
 None
F1P  A 702 (-3.8A)
None
 0.85A 3k4vA-4bb9A:
undetectable		 3k4vA-4bb9A:
11.21
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4G0U_B_ASWB1301_1
(DNA TOPOISOMERASE
2-BETA)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		4 / 7 ILE A 219
ARG A 215
GLY A 181
ALA A 188
 None
None
F1P  A 702 (-3.6A)
None
 0.91A 4g0uB-4bb9A:
undetectable		 4g0uB-4bb9A:
23.52
Potential target for repurposing, i.e. matched protein structure has less than 30% sequence identity to known drug target, and may potentially interact with the same drug molecule based on local structural similarity of binding site.
4R1Z_A_AERA601_1
(CYP17A1 PROTEIN)		 4bb9 GLUCOKINASE
REGULATORY PROTEIN
(Homo
sapiens) 		5 / 9 ALA A 230
SER A 110
ILE A 178
GLY A 181
VAL A 187
 None
F1P  A 702 (-2.6A)
None
F1P  A 702 (-3.6A)
None
 1.06A 4r1zA-4bb9A:
undetectable		 4r1zA-4bb9A:
22.00